Navigation Links
Science Finds Way to Block Booze's Effect -- in Worms

WEDNESDAY, July 16, 2014 (HealthDay News) -- Scientists who created worms that can't get drunk say their research could lead to new ways to treat people with drinking problems.

The research team inserted a modified human alcohol target into the worms. An alcohol target is a nervous system molecule that binds alcohol. There are many types of these molecules.

"This is the first example of altering a human alcohol target to prevent intoxication in an animal," corresponding author Jon Pierce-Shimomura, an assistant professor in the College of Natural Sciences and Waggoner Center for Alcohol and Addiction Research at the University of Texas at Austin, said in a university news release.

Pierce-Shimomura even suggested that this target could be used to develop a "James Bond"-type spy drug that could allow someone to outdrink an opponent without feeling the effects of alcohol.

An important feature of the modified alcohol target -- called the BK channel -- used in this study is that the mutation only changes the response to alcohol. It doesn't affect other important functions such as regulating the activity of nervous system cells, blood vessels, the bladder and the respiratory tract.

"We got pretty lucky and found a way to make the channel insensitive to alcohol without affecting its normal function," Pierce-Shimomura said.

The research could lead to the development of drugs to treat alcoholism.

"Our findings provide exciting evidence that future pharmaceuticals might aim at this portion of the alcohol target to prevent problems in alcohol abuse disorders," he said. "However, it remains to be seen which aspects of these disorders would benefit."

The study was published online July 15 in The Journal of Neuroscience.

Scientists note that research involving animals often fails to produce similar effects on humans.

More information

The U.S. National Library of Medicine has more about alcoholism and alcohol abuse.

SOURCE: University of Texas at Austin, news release, July 15, 2014


Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Miraca Life Sciences’ PathConnect System Achieves ONC HIT 2014 Edition Modular EHR Certification from ICSA Labs
2. Interactive Solar Exhibit at LEGOLAND Teaches Children Science, Technology, Engineering & Math (STEM) Skills
3. Seven Healthcare Startups Selected to Participate in University City Science Center’s First Digital Health Accelerator
4. Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at
5. Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science
6. Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at
7. Study of dermatology on YouTube shows new ways science reaches public
8. UMMS scientist named 2014 Pew Latin American Fellow in the biomedical sciences
9. Science and engineering stars shine
10. Crescendo Bioscience to present multiple studies at 2014 EULAR Meeting
11. New from Garland Science -- now available: Genetics and Genomics in Medicine
Post Your Comments:
Related Image:
Science Finds Way to Block Booze's Effect -- in Worms
(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... 2016 , ... EB Medicine presented its first-ever “Issue of ... in Ponte Vedra Beach, FL. The awards honor the outstanding work of leading ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the efforts ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... MEDIA, Pa. , June 23, 2016 ... treatments in an outpatient dialysis facility.  Treatments are usually ... to 6 hours per visit, including travel time, equipment ... on a patient, but especially grueling for patients who ... residents of a skilled nursing and rehabilitation centers for ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
(Date:6/23/2016)... , June 23, 2016  The National Pharmaceutical ... joined the health policy research organization as its ... , MD, senior vice president and chief scientific ... representative on the NPC Board of Directors. ... that Mallinckrodt has joined us in support of ...
Breaking Medicine Technology: