Navigation Links
Science Finds Way to Block Booze's Effect -- in Worms
Date:7/16/2014

WEDNESDAY, July 16, 2014 (HealthDay News) -- Scientists who created worms that can't get drunk say their research could lead to new ways to treat people with drinking problems.

The research team inserted a modified human alcohol target into the worms. An alcohol target is a nervous system molecule that binds alcohol. There are many types of these molecules.

"This is the first example of altering a human alcohol target to prevent intoxication in an animal," corresponding author Jon Pierce-Shimomura, an assistant professor in the College of Natural Sciences and Waggoner Center for Alcohol and Addiction Research at the University of Texas at Austin, said in a university news release.

Pierce-Shimomura even suggested that this target could be used to develop a "James Bond"-type spy drug that could allow someone to outdrink an opponent without feeling the effects of alcohol.

An important feature of the modified alcohol target -- called the BK channel -- used in this study is that the mutation only changes the response to alcohol. It doesn't affect other important functions such as regulating the activity of nervous system cells, blood vessels, the bladder and the respiratory tract.

"We got pretty lucky and found a way to make the channel insensitive to alcohol without affecting its normal function," Pierce-Shimomura said.

The research could lead to the development of drugs to treat alcoholism.

"Our findings provide exciting evidence that future pharmaceuticals might aim at this portion of the alcohol target to prevent problems in alcohol abuse disorders," he said. "However, it remains to be seen which aspects of these disorders would benefit."

The study was published online July 15 in The Journal of Neuroscience.

Scientists note that research involving animals often fails to produce similar effects on humans.

More information

The U.S. National Library of Medicine has more about alcoholism and alcohol abuse.

SOURCE: University of Texas at Austin, news release, July 15, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Miraca Life Sciences’ PathConnect System Achieves ONC HIT 2014 Edition Modular EHR Certification from ICSA Labs
2. Interactive Solar Exhibit at LEGOLAND Teaches Children Science, Technology, Engineering & Math (STEM) Skills
3. Seven Healthcare Startups Selected to Participate in University City Science Center’s First Digital Health Accelerator
4. Americas Transcatheter Heart Valves Market 2020 Forecasts in New Research Report at LifeScienceIndustryResearch.com
5. Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science
6. Global Cognitive Assessment & Training Market: 27.3% CAGR to 2018 Says a New Research Report Available at LifeScienceIndustryResearch.com
7. Study of dermatology on YouTube shows new ways science reaches public
8. UMMS scientist named 2014 Pew Latin American Fellow in the biomedical sciences
9. Science and engineering stars shine
10. Crescendo Bioscience to present multiple studies at 2014 EULAR Meeting
11. New from Garland Science -- now available: Genetics and Genomics in Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Science Finds Way to Block Booze's Effect -- in Worms
(Date:12/6/2016)... ... December 06, 2016 , ... An ... much-anticipated HydroFX for Water®. This first-of-its-kind water-soluble powder supplement has a unique ... most powerful antioxidants, molecular hydrogen, HydroFX for Water transforms every day water ...
(Date:12/6/2016)... (PRWEB) , ... December 06, 2016 , ... Keeping Gift ... people choose gifts that are safe and age-appropriate for their recipients. This is the ... to reflect on the safety of items that would make good gifts for children. ...
(Date:12/6/2016)... ... December 06, 2016 , ... Specialty Technical Publishers (STP) ... Audit Protocol Consortium (IAPC) EHS audit protocol for Great Britain . Leading ... of their EHS regulatory obligations and rapidly collect, share, archive, and export audit ...
(Date:12/6/2016)... ... 06, 2016 , ... The OSHA Training Center at ... Center headquartered in Northern California, has announced the addition of a Public Sector ... training to public sector employees. , “The primary goal of the Public Sector ...
(Date:12/6/2016)... ... December 06, 2016 , ... U.S. Security Associates (USA) was ... for their industry leading training methods that engage their associates and link their ... global elite in employer-sponsored training and development programs. , “The 2017 Training Top ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Ill. , Dec. 5, 2016 For ... score on the 2017 Human Rights Campaign Foundation,s ... The CEI is a national benchmarking tool used to ... bisexual, and transgender (LGBT) employee equality. For ... Survey to help companies gauge their equality efforts, culture ...
(Date:12/5/2016)... Eisai Inc. announced today new analyses and ... of the American Epilepsy Society (AES). ... adjunctive therapy for the treatment of partial onset seizures ... generalized tonic-clonic seizures (PGTC) in patients with epilepsy who ... Important Safety Information for FYCOMPA, including Boxed WARNING for ...
(Date:12/5/2016)... Dec. 5, 2016  Seno Medical Instruments, Inc., the ... new tool to improve the process of diagnosing breast ... its European MAESTRO post-market surveillance and clinical follow-up study ... (SABCS) taking place from December 6-10, 2016 at ... San Antonio, Texas . Seno Medical ...
Breaking Medicine Technology: