Navigation Links
Schizophrenia Gene's Role May Be Broader, More Potent, than Thought
Date:11/19/2009

UCSF scientists studying nerve cells in fruit flies have uncovered a new function for a gene whose human equivalent may play a critical role in schizophrenia.

(Vocus) November 19, 2009 -- UCSF scientists studying nerve cells in fruit flies have uncovered a new function for a gene whose human equivalent may play a critical role in schizophrenia.

Scientists have known that the mutated form of the human gene – one of three consistently associated with schizophrenia – mildly disrupts the transmission of chemical signals between nerve cells in the brain.

The new study focuses on genes involved in “adaptive plasticity,” the capacity of nerve cells to compensate for a wide range of perturbations and continue to function normally.

Studies ranging from fruit flies to human have shown that if a nerve cell is functionally impaired then the surrounding cells can compensate and restore normal cell-to-cell communication. This type of “adaptive plasticity” stabilizes brain function, but the molecules involved remain largely unknown.

In the current study, the team screened 276 mutated, or disabled, fly genes to determine if their absence revealed a role in adaptive plasticity in the fruit fly nervous system. While absence of most of the genes had no impact on adaptive plasticity, the absence of the gene known as dysbindin did.

The finding, reported in the November 20, 2009 issue of Science, was dramatic, says the senior author of the study, Graeme Davis, PhD, Albert Bowers Endowed Professor and Chair of the Department of Biochemistry and Biophysics at UCSF.

“Mutation of the gene completely prevented the capacity of the neural c
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. APA Comments on FDAs First Approval of Medication to Treat Pediatric Schizophrenia and Bipolar Disorder
2. Normal role for schizophrenia risk gene identified
3. Schizophrenia Gene May Have On/Off Switch
4. Potential new approach to treat cognitive impairments in schizophrenia
5. Schizophrenia candidate genes affect even healthy individuals
6. Hearing messages embedded in noise could be early sign of schizophrenia
7. People with Schizophrenia More Likely to Die of Heart Disease, Reports the Harvard Mental Health Letter
8. US FDA approves ABILIFY for adolescent patients with schizophrenia
9. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for Adolescent Patients With Schizophrenia
10. Study Shows Organons Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia
11. Genes Yield More Clues to Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... planning to phase out junk food and make exercise mandatory, ... Department to counter childhood obesity//. , ,These recommendations follow ... were being sent to dieticians. , ,The NSW report, ... the biggest study of its kind in the country. The ...
... been awarded with discount shopping cards in return for ... clinic as part of the HIV/AIDS awareness program//. ... Nation's AIDS-prevention agency India has largest number of people, ... virus. ,Sushena Reza-Paul of the Karnataka Health ...
... Pradesh today in protest against dismissal of AIIMS director ... junior doctors observed a `symbolic' strike and a large ... some time condemning the sacking of Venugopal., ,Terming ... the strike was "symbolic and we have no intention ...
... Manchester is reportedly treating patients with mouth and throat cancer ... ,Sources at the Manchester cancer hospital explained that ... doctors at Christie Hospital in Didsbury, Manchester, are planning to ... clinical trail basis. They hope to try and reduce the ...
... expressed their concerns over the practice of "Breast Ironing" ... is used to stunt breast growth in girls by mothers// ... own good. ,It is aimed at warding off ... objects pressed against the developing breasts in teenaged girls. "Breast ...
... is brandishing a piece of his own skull, an ... visitors//. ,The Jawaharlal Nehru Memorial Hospital in Kalyani, ... no less visitors than any museum these days with ... getting electrocuted from a high-voltage wire, holding his own ...
Cached Medicine News:Health News:Man Holds Own Skull in Bengal Medical Miracle 2
(Date:12/15/2014)... , Dec. 15, 2014  Colorado and Washington ... legalized adult use of cannabis. Oregon , ... ended prohibition during the November 2014 elections. ... - http://photos.prnewswire.com/prnh/20141212/164153LOGO The benefits of ... and obvious benefits like the increased tax revenue for state ...
(Date:12/15/2014)... As medical device manufacturers join pharmaceutical companies ... standard, content teams have a greater role to play ... the standard. Starting January 2015, Data Conversion Laboratory (DCL) ... benefits and the critical aspects of implementing SPL. ... Howard Shatz , DCL,s SPL expert, and will ...
(Date:12/15/2014)... 15, 2014   DaVita HealthCare Partners Inc. ... nation,s largest and most innovative health care communities, ... DaVita Clinical Research  (DCR) and  HealthCare Partners Clinical ... its extensive clinical research and data analytics services, ... and end-stage renal disease (ESRD), as well as ...
Breaking Medicine Technology:CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 2DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 4
... Inc. (Nasdaq: MEDH ), formerly CBaySystems Holdings ... for the U.S. healthcare system, today announced the closing ... its common stock.  The shares began trading on February ... ticker symbol MEDH. In the offering, ...
... SPRING, Md., Feb. 11, 2011 The U.S. Food ... the first X-ray mammography device that provides three-dimensional (3-D) ... diagnosis. (Logo:   http://photos.prnewswire.com/prnh/20090824/FDALOGO ) ... the breast that is the best tool for early ...
Cached Medicine Technology:MedQuist Holdings Inc. Announces Closing of Its Initial U.S. Public Offering and Acquisition of Additional Shares of MedQuist Inc. 2MedQuist Holdings Inc. Announces Closing of Its Initial U.S. Public Offering and Acquisition of Additional Shares of MedQuist Inc. 3FDA Approves First 3-D Mammography Imaging System 2
... Advanced Technologies, The UroMax Ultra ia ... of high pressure and low profile., ... yields a remarkably strong material that ... balloon materials., Non-Compliant Balloons, A compliant ...
... Fr Straight Channel; 33 or 42 cm ... Operating Ureteroscopes offer a small distal diameter ... to the ureter for diagnosis and treatment. ... ideal for large operating instruments, mechanical (Lithoclast) ...
... Small 6.9 Fr Diameter with Two ... ,MICRO-6L Long Semi-Rigid Ureteroscope, with a longer ... ureteroscope with two large working channels for ... allow you to basket a stone and ...
... The ACMI USA Series DUR-8 Durable Flexible ... the entire intrarenal collecting system with little ... superior secondary deflection allow complete intrarenal access, ... facilitates access to the proximal ureter and ...
Medicine Products: