Navigation Links
Schizophrenia: A disorder of neurodevelopment and accelerated aging?
Date:3/7/2013

Philadelphia, PA, March 6, 2013 Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections. Numerous findings in brain imaging studies describe the changes in brain structure and function associated with schizophrenia as emerging early in the course of the disorder. Some early brain imaging studies even found little or no evidence of progression of structural deficits.

Yet, a new generation of studies now also describes degenerative processes in schizophrenia that resemble accelerated aging. Schizophrenia is associated with an increased risk of cardiovascular illnesses and persons with schizophrenia have shorter average lifespans. Studies have also found that individuals with schizophrenia have shortened telomeres, a marker of aging. Structural imaging studies describe enhanced reductions in gray and white matter volumes and increased cortical thinning with age associated with schizophrenia. Similar findings have also emerged for individuals diagnosed with major depressive disorder.

This evidence led researchers of a new study in Biological Psychiatry to specifically examine age-related decline in cerebral white matter in schizophrenia and major depressive disorder, using a measure of microstructural integrity called fractional anisotropy. For comparison, they recruited two normal control groups, one for each cohort.

Dr. Peter Kochunov, first author of the study, explained their findings: "This study showed that the brain's white matter, or the wiring of the brain, ages faster in patients with schizophrenia compared with people who do not have a mental illness. In comparison, the white matter in people with major depression ages similarly to people without a mental illness."

"We are getting a clear picture that a component of the biology of schizo
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Family intervention improves mood symptoms in children and adolescents at risk for bipolar disorder
2. 7 genetic risk factors found to be associated with common eye disorder
3. Ohio Psychological Association Partners with Columbus State Community College for National Eating Disorders Awareness Week
4. Stress Disorder May Be Common Among ICU Patients on Ventilators
5. H1N1 Swine Flu Vaccine Tied to Sleep Disorder in British Children
6. Police and firefighters at higher risk for mental disorders following traumatic events
7. Gut microbiota plays important role in functional bowel disorders
8. Gene Disorder Screen Benefits Baby Boys, Girls Equally: Study
9. Spiro PD Personal Spirometer Helps People Track Their Breathing Disorders As Generally Mild Winter Signals Early Allergy Season
10. UCLA study finds endocrine disorder is most common cause of elevated calcium levels
11. Pitt study examines cost-effectiveness of medicare drug plans in schizophrenia and bipolar disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... March 27, 2015 According to a ... ), the plate and screw market in Europe is ... generic plate and screw segment. Price decreases are being ... representing almost 50% of the total European trauma device ... the total market value, year after year. , ...
(Date:3/27/2015)... San Francisco, CA (PRWEB) March 27, 2015 ... Day) Recovery Yoga for functional fitness athletes. This new ... creates a specific protocol for post-workout cool down. This ... mobility, promote breath control and mental focus. , ... said: “I started practicing yoga long before I started ...
(Date:3/27/2015)... Naples, FL and London, UK (PRWEB) March 27, 2015 ... solution, announced today that it has appointed Sean Fitzgerald, ... the role of Chief Operating Officer and Interim Chief ... Vice President of leading education technology innovator, EverFi, backed ... Eric Schmidt, and Twitter founder Evan Williams. Prior to ...
(Date:3/27/2015)... California’s ongoing worst ever drought, and the ... United States Northeast, are both manifestations of the same ... creating changes in the atmosphere’s “energy balance,” according to ... researcher, speaking on the Sharon Kleyne Hour™ Power of ... warmer and dryer global climate but also greater and ...
(Date:3/27/2015)... Trail mix is the perfect, healthy snack for ... and during the game! It’s portable, lightweight and provides a ... introduce a new line of specialty trail mixes that satisfy ... selections packed with nutritious, 100% all natural ingredients. , These ... add protein and fiber to your diet and boost energy. ...
Breaking Medicine News(10 mins):Health News:Titanium Trauma Treatment Devices in Europe Becoming More Affordable, Decreasing Market Value: Group Purchasing Further Eroding Selling Prices 2Health News:Titanium Trauma Treatment Devices in Europe Becoming More Affordable, Decreasing Market Value: Group Purchasing Further Eroding Selling Prices 3Health News:Endure Yoga Introduces WOD Recovery Yoga 2Health News:GenSight Appoints Former Technology Executive as Chief Operating Officer 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 3Health News:Aurora Product, Inc. Introduces New Line of Specialty Trail Mixes 2
... examination is its limited capacity to determine the ... between benign and malignant lymph nodes and focal ... difficult and frequently requires EUS-guided fine needle aspiration ... been presented as a novel technique that can ...
... Calgary, AB- The most disabling aspect of Tourette syndrome ... conjunction with another disorder. The most frequent co-occurring ... disorder (ADHD), though the cause of this association is ... but having two means coping with more than twice ...
... risky behaviors, study finds , , WEDNESDAY, April 15 (HealthDay News) ... children are more likely to slip into trouble, from getting ... study has found. , But adolescents whose mothers reported that ... fare better. , "Adolescents are in that difficult time of ...
... Hard Post-Spring BreakLYNBROOK, N.Y., April 15 ... other technicians at Arrow Exterminating are finding bed bugs ... keyboards, between the pages of books, inside electric switches, ... cell phone. "We,ve never seen anything like this," ...
... Based on its recent analysis of the ... (CT) markets market, Frost & Sullivan recognizes Zecotek ... & Sullivan Award for Enabling Technology. Zecotek,s outstanding ... solid-state photo detector technologies that will help deliver ...
... EPS Growth of 15.9 Percent (GAAP EPS Growth of 53.3 Percent) ... Dividend by 11 Percent - , , ABBOTT ... today announced financial results for the first quarter ended March 31, ... Diluted earnings per share, excluding specified items, were $0.73, reflecting ...
Cached Medicine News:Health News:Can EUS elastography help distinguish benign from malignant tissue? 2Health News:Tourette syndrome misconceptions only one battle for patients 2Health News:Deployment Takes Toll on Military Moms and Teens 2Health News:Deployment Takes Toll on Military Moms and Teens 3Health News:Bed Bug Infestation an Epidemic; Bugs Found in Cell Phone, TVs and Keyboards 2Health News:Bed Bug Infestation an Epidemic; Bugs Found in Cell Phone, TVs and Keyboards 3Health News:Frost & Sullivan Recognizes Zecotek Photonic's Medical Imaging Achievement, Development of Next-Generation Scintillation Crystals and Photo Detector Technology 2Health News:Frost & Sullivan Recognizes Zecotek Photonic's Medical Imaging Achievement, Development of Next-Generation Scintillation Crystals and Photo Detector Technology 3Health News:Frost & Sullivan Recognizes Zecotek Photonic's Medical Imaging Achievement, Development of Next-Generation Scintillation Crystals and Photo Detector Technology 4Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 2Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 3Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 4Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 5Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 6Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 7Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 8Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 9Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 10Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 11Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 12Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 13Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 14Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 15Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 16Health News:Abbott Reports 16 Percent Earnings Growth in First Quarter; Confirms Double-Digit Earnings Growth Outlook for 2009 17
(Date:3/27/2015)... March 27, 2015 BioCorRx, Inc. ( ... Ana, California is a healthcare solutions organization, which ... estimated at $22 billion in the U.S. alone. The Company ... FDA-approved Naltrexone in a specially compounded form for outpatient surgical ... and New Zealand ) to ...
(Date:3/27/2015)... 2015 Across the global healthcare landscape, the ... clinical development, market education, and regulatory compliance. As emerging ... function is expected to increase in prominence and follow ... According to research by benchmarking firm, Best Practices, LLC, ... to Medical Affairs. Among companies in India ...
(Date:3/27/2015)...  The quality function within the medical device sector ... standards at every stage of the product life cycle. ... have the challenge of balancing quality and safety with ... effectively balance these priorities risk funding and staffing for ... regulatory scrutiny. For the third consecutive year, ...
Breaking Medicine Technology:Small Cap IR Correction -- BioCorRx Inc. Positions Itself Through Strategic Partnerships To Gain Market Share Of The $22 Billion Substance Abuse Treatment Market In The U.S. 2Medical Affairs Capabilities Expanding in Emerging Marketplaces 2New Medical Device Quality Study Finds Regulatory Environment is Boosting Quality Spending, Especially for Large Companies 2
Supplied sterile in peel-open packages. Intended for one-time use....
... and exchange in endourological procedures. The increased ... allows utilization of an extra heavy duty ... very flexible tip. The proximal end of ... coiled wire guide manufactured by Cook®. Supplied ...
Supplied sterile in peel-open packages. Intended for one-time use....
Supplied sterile in peel-open packages. Intended for one-time use....
Medicine Products: