Navigation Links
Schering-Plough Announces FDA Approval of PEGINTRON(TM) and REBETOL(R) Combination Therapy for Treating Pediatric Hepatitis C
Date:12/12/2008

han 40%) in adult patients receiving either PEGINTRON or PEGINTRON/REBETOL are injection site inflammation/reaction, fatigue/asthenia, headache, rigors, fevers, nausea, myalgia, and anxiety/emotional lability/irritability. Most common adverse reactions (more than 25%) in pediatric patients receiving PEGINTRON/REBETOL are pyrexia, headache, neutropenia, fatigue, anorexia, injection site erythema and vomiting.

In a study with PEGINTRON/REBETOL (weight-based) combination therapy in adult patients, anemia with weight-based dosing was 29%; however, the majority of these cases were mild and responded to dose reductions. The incidence of serious adverse reactions reported for the weight-based REBETOL group was 12%. In many but not all cases, adverse reactions resolved after dose reduction or discontinuation of therapy. Some patients experienced ongoing or new serious adverse reactions during the 6-month follow-up period. Discontinuations for adverse events were 15% and were related to known interferon effects of psychiatric, systemic (e.g., fatigue, headache), or gastrointestinal adverse reactions. Dose modifications due to adverse reactions occurred in 29% of patients.

Most common adverse reactions with PEGINTRON/REBETOL (weight-based) combination therapy were psychiatric which occurred among 68-69% of patients. These psychiatric adverse reactions included most commonly depression, irritability, and insomnia, each reported by approximately 30-40% of subjects in all treatment groups. Suicidal behavior (ideation, attempts and suicides) occurred in 2% of all patients during treatment or during follow-up after treatment cessation. PEGINTRON induced fatigue or headache in approximately two-thirds of patients, with fever or rigors in approximately half of the patients. The severity of some of these systemic symptoms (e.g., fever and headache) tends to decrease as treatment continues. There was a 23-24% incidence overall for
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
2. Schering-Plough Schedules Conference Call and Webcast for 2007 Third Quarter Earnings
3. Schering-Plough Reports Financial Results for Third Quarter of 2007
4. Schering-Plough CEO Calls for Four-Pronged Approach to Improving Current Health Care Environment
5. Schering-Plough Reports U.S. District Court for District of Massachusetts Finds No Liability for Subsidiary in AWP Case
6. Schering-Plough to Webcast CFO Robert J. Bertolinis Presentation at 2007 Credit Suisse Health Care Conference
7. Schering-Plough Receives Clearance From U.S. Federal Trade Commission for Planned Acquisition of Organon Biosciences N.V.
8. Schering-Plough Declares Quarterly Dividends on Common Shares and 2007 Mandatory Convertible Preferred Stock
9. Centocor, Schering-Plough Revise Agreement Covering REMICADE, Golimumab
10. Schering-Plough Board Elects Dr. Craig B. Thompson as a Director
11. Schering-Plough CEO to Buy $2 Million in Common Shares
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... Energy Textiles has recently added a ... is now available online, and Energy Textile is providing ... infrared-active athletic gear over compression gear. , The ... been signed for Under Armour to provide team gear ... years. In light of this decision, Energy Textiles contemplates ...
(Date:10/31/2014)... (HealthDay News) -- Sleep apnea may make it hard for ... your car or left your house keys, a small study ... showed that this ability -- called spatial memory -- was ... even when other stages of sleep weren,t affected. REM sleep ... occur. "We,ve shown for the first time that sleep ...
(Date:10/31/2014)... duration of treatment and cost, patients with early ... breast irradiation (APBI) with proton therapy versus whole ... The University of Texas MD Anderson Proton Therapy ... study based on typical patient characteristics, researchers used ... eight different types of partial and whole breast ...
(Date:10/31/2014)... out of four older Americans say that either they ... medical treatment, according to the latest issue of The ... Report ( PP&AR ), which goes on to ... they fail to honor patients, end-of-life health care wishes. ... Care: Issues and Options ," features 12 articles that ...
(Date:10/31/2014)... Gold Medal Wine Club is making ... gifts for the wine novice and enthusiasts on their lists ... Special , which Early Bird shoppers receive discounts as high ... membership. , Gift Givers must place their orders before ... discounts, Gold Medal Wine Club adds more value to its ...
Breaking Medicine News(10 mins):Health News:Compression Gear--Is There a Better Alternative? 2Health News:Compression Gear--Is There a Better Alternative? 3Health News:Compression Gear--Is There a Better Alternative? 4Health News:Sleep Apnea May Steal Some of Your Memory: Study 2Health News:Proton therapy shown to be less costly than some alternative radiotherapy techniques 2Health News:Proton therapy shown to be less costly than some alternative radiotherapy techniques 3Health News:Advance directives can benefit patients, families, and health care system 2Health News:Gold Medal Wine Club now offering Early Bird Gift Giving Special for Holidays 2
... especially when the pollen count is high in the atmosphere. ... every year. In almost 38 million people, congestion and post ... infections. Newer treatments are now availble to combat such an ... Head and Neck Surgeon at , of Methodist Dallas Medical ...
... shows thickening of the heart may put young people at ... heart muscle protein // and is noticeable after the growth ... of breath on exertion, and a family history of sudden ... hypertrophic cardiomyopathy, can be seen on an electrocardiogram, but formal ...
... that overweight women might want to shed those extra pounds ... to // have a false-positive finding on a routine mammogram. ... those of normal weight to get breast cancer and also ... study exists on the accuracy of mammograms in overweight and ...
... but new research shows postmenopausal women who exercise have ... cholesterol levels. ,For the study researchers included 50 ... medications and had no diseases that affect bone metabolism. ... week for 26 months as well as two at-home ...
... fibrillation run a higher risk of stroke than those ... causes blood to pool, which can lead to a ... A new test to monitor people for irregular heartbeats ... ,Investigators evaluated about 150 patients who had just suffered ...
... world’s second leading cause of blindness. More than 66 ... research suggests doctors need to do more than just ... glaucoma. Researchers say examination of the optic nerve ... not someone has early stage glaucoma. ,Researchers say ...
Cached Medicine News:
(Date:10/31/2014)... Mast Therapeutics, Inc. (NYSE MKT: MSTX), a ... quarter ended September 30, 2014. Brian ... third quarter was productive for Mast. Consistent with prior guidance, ... sickle cell disease is on track to complete enrollment ... 50 study sites in the U.S. and more than ...
(Date:10/31/2014)... Today, Analysts Review released its ... ), Bristol-Myers Squibb Co. (NYSE: BMY ), ... SA (NYSE: SNY ) and Actavis plc ... of publication. To reserve complementary membership, limited openings are ... Research Reports ,On October 23, 2014, Celgene Corporation (Celgene) ...
(Date:10/31/2014)...  Encision Inc. (OTCQB:ECIA), a medical device company owning ... in minimally invasive surgery, today announced financial results for ... The Company posted quarterly net revenue of ... thousand, or $(0.04) per share. These results compare to ... of $50 thousand, or $(0.01) per share, in the ...
Breaking Medicine Technology:Mast Therapeutics Reports Third Quarter 2014 Financial Results 2Mast Therapeutics Reports Third Quarter 2014 Financial Results 3Mast Therapeutics Reports Third Quarter 2014 Financial Results 4Mast Therapeutics Reports Third Quarter 2014 Financial Results 5Mast Therapeutics Reports Third Quarter 2014 Financial Results 6Mast Therapeutics Reports Third Quarter 2014 Financial Results 7Mast Therapeutics Reports Third Quarter 2014 Financial Results 8Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 2Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 3Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 4Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 5Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 6Encision Reports Second Quarter Fiscal Year 2015 Results 2Encision Reports Second Quarter Fiscal Year 2015 Results 3Encision Reports Second Quarter Fiscal Year 2015 Results 4Encision Reports Second Quarter Fiscal Year 2015 Results 5
... ATLANTA, July 18, 2011 Among the many new features ... with a simple way to deliver highly conformal stereotactic plans ... a target as the treatment beam rotates around the patient. ... Food and Drug Administration. "DCA can be used ...
... Caliper Life Sciences, Inc. (NASDAQ: CALP ... life science companies, today announced that Kevin Hrusovsky, President ... Stock Market Opening Bell on Tuesday, July 19th and ... customers to participate in this special event. This event ...
Cached Medicine Technology:New Release of Elekta's Monaco Treatment Planning System Prepares Software for Stereotactic Radiation Therapy 2Caliper Life Sciences to Ring The NASDAQ Stock Market Opening Bell on Tuesday, July 19 2Caliper Life Sciences to Ring The NASDAQ Stock Market Opening Bell on Tuesday, July 19 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: