Navigation Links
Scarring May Raise Death Risk From Fatty Liver Disease
Date:4/16/2013

TUESDAY, April 16 (HealthDay News) -- Advanced fibrosis -- or progressive scarring of the liver -- is tied to higher death rates from a type of fatty liver disease found in people who drink little or no alcohol, according to a new study.

This increased mortality is primarily due to heart-related causes, not nonalcoholic fatty liver disease alone, the researchers said. The study was published in the April issue of the journal Hepatology.

"Our findings confirm that [nonalcoholic fatty liver disease] patients without advanced fibrosis do not have higher mortality risk," lead study investigator Dr. W. Kim Ray, of the Mayo Clinic in Rochester, Minn., said in a journal news release. "Careful monitoring of disease progression in patients with [nonalcoholic fatty liver disease] and fibrosis, along with interventions that reduce cardiovascular risk factors, are warranted."

The study involved data on more than 11,000 people from a large national survey compiled by the U.S. National Center for Health Statistics and the U.S. Centers for Disease Control and Prevention from 1988 to 1994. Researchers also included follow-up data on deaths through 2006.

Thirty-four percent of the participants had nonalcoholic fatty liver disease. Of these people, 72 percent did not have significant scarring or fibrosis. Meanwhile, 3 percent were affected by advanced fibrosis.

Although nonalcoholic fatty liver disease was not linked to an increase in death rates after 15 years, mortality increased as scarring progressed. The patients with advanced scarring had a 69 percent increase in mortality compared with those without scarring of the liver.

Nonalcoholic fatty liver disease was diagnosed by ultrasound. Fibrosis scores were used to rate the severity of organ scarring.

"The effect of [nonalcoholic fatty liver disease] on public health is not well understood," Ray said. "Large, population-based studies, which can provide insight into disease activity, present some difficulty given that liver biopsy is required to confirm [nonalcoholic fatty liver disease]."

As obesity rates have doubled in the United States during the past 25 years, so has the incidence of nonalcoholic fatty liver disease, making it the most prevalent liver disease in the United States, according to the news release.

More information

The American Liver Foundation has more about nonalcoholic fatty liver disease.

-- Mary Elizabeth Dallas

SOURCE: Hepatology, news release, April 10, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Breakthrough treatment reduces post-surgical scarring for glaucoma patients
2. Researchers prevent cancer spread by blocking tissue scarring
3. Scans That Gauge Heart Scarring May Spot High-Risk Patients
4. Heart Scarring May Be More Dangerous Than Thought, Study Suggests
5. Depo-Provera Birth Control Might Raise Breast Cancer Risk
6. Cancer Diagnosis May Raise Odds for Suicide, Heart Attack Death
7. Infection Might Raise Blood Clot Risk for Older Adults: Study
8. Feeling Trapped, Obligated Raises Odds of Job Burnout: Study
9. Spouses of Cancer Patients May Have Raised Risk of Heart Disease, Stroke
10. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
11. Childhood Obesity May Raise Odds of Adult Liver Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scarring May Raise Death Risk From Fatty Liver Disease
(Date:4/28/2017)... , ... April 28, 2017 , ... ... announce the integration of Microsoft(R) Word(TM) Online(TM), which enables sleep physicians to create ... it streamlines the reporting process and provides a familiar interface that does not ...
(Date:4/28/2017)... ... ... sleep affects much more than energy – it also has mental and physical benefits. According ... reaction time, which can increase the risk of having a car accident. , This ... NSF to help you sleep better and feel better:, , Turn ...
(Date:4/28/2017)... ... April 28, 2017 , ... Ushio America proudly ... offer an instant energy-saving solution for F32T8 fluorescent lamps on most instant-start and ... These 50,000 hour rated lamps utilize the existing electronic ballast, saving labor and ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... exposed to more adverse experiences than children in the general population. That’s because ... abuse, neglect or other family challenges. While no fault of their own, youth ...
(Date:4/28/2017)... ... April 28, 2017 , ... Early detection ... improve drug safety and minimize the cost of development. In this webinar, sponsored ... using cell lines and for cardiac toxicity using induced pluripotent stem cells (iPSCs). ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... 20, 2017   ZappRx, Inc ., a digital health ... process, today announced it closed $25 million in Series B ... firm based in Seattle that is ... . The Series B round included participation from SR ... and GV (formerly Google Ventures). As part of ...
(Date:4/20/2017)... -- Eyevensys, a private biotechnology company developing ... technology that enables the safe, local, sustained production of ... range of ophthalmic diseases, announces it has received approval ... (MHRA) to advance its technology into clinical development. ... The EyeCET platform ...
Breaking Medicine Technology: