Navigation Links
Scans spot hidden tumors in rare cancer syndrome
Date:3/18/2008

ls with LFS, the chance of developing any cancer has been estimated at 50 percent by age 30, and 90 percent by age 60. A survivor of one cancer has a high risk of developing a new malignancy over time.

The syndrome is usually diagnosed after several members of a family develop early-onset tumors, prompting a test for the mutated gene. At present, there is no specific screening test to detect cancers before they become symptomatic in people carrying the Li-Fraumeni mutation because they are prone to such a wide variety of cancer types.

"We decided to study this in the adult LFS population because PET/CT scanning is used in the care of many of the type cancers that occur in LFS. Both LFS families and physicians have been frustrated by the lack of information for families with a rare and burdensome condition," said Judy Garber, MD, MPH, senior author of the paper and director of Dana-Farber's Cancer Risk and Prevention Clinic.

The pilot study recruited 15 healthy members of Li-Fraumeni families carrying the TP53 mutation and who had not been diagnosed with cancer in the past five years. Many of the volunteers were members of Li-Fraumeni families who had participated in research through Dana-Farber and the NCI for many years.

The combined PET/CT images revealed thyroid cancer in a 31-year-old breast cancer survivor and in a 48-year-old survivor of breast cancer and a childhood sarcoma. In addition, a 36-year-old man with no cancer history was found to have a tumor at the junction of his esophagus and stomach. All were given potentially curative treatments, the researchers said. Subjects are currently being followed one year later.

Whether earlier detection of tumors in LFS patients will translate into increased survival remains to be shown in longer-term studies, the scientists said. Another uncertainty is whether the potential benefit from periodic screening would outweigh the risks that the radiation exposure might trigger
'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. European directive will halt use of MRI scans; cancer diagnosis and treatment will suffer
2. PET scans can accurately detect a breast tumors response to chemotherapy
3. High-tech CT scans: not a bad choice to test for clogged arteries
4. New Computerized Scans Effective for Spotting Clogged Arteries
5. PET scans useful for some cancer treatment, but how do patients fare?
6. PET Scans Can Spot Cervical Cancers Return
7. Post-treatment PET scans can reassure cervical cancer patients
8. CT scans to determine heart disease in the emergency room
9. Obesity Keeps Patients From Needed CT Scans After Surgery
10. PET Scans Could Boost Lung Cancer Diagnosis
11. Rise in CT Scans Poses Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... July 31, 2015 , ... Easter Seals Southern Georgia’s Heels & Wheels Duathlon & Triathlon ... time will be 7:30 AM. The duathlon is a 2 mile run, 13 mile bike ... Walker Lake, a 13 mile bike, and a 3 mile run. Heels & Wheels ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... and the growing number of individuals who remain undiagnosed, treatment options for patients ... shy away from traditional CPAP therapy due to its overall lack of comfort ...
(Date:7/30/2015)... ... July 31, 2015 , ... On July 22nd the Bradenton Herald ... plausible solutions for controlling the heroin outbreak. Ultimately the committee expressed lack of funding, ... perpetuating the heroin crisis in North Florida. The task force has proposed to instate ...
(Date:7/30/2015)... ... ... OSF Healthcare System has been recognized as one of the nation’s ... & Health Networks. This marks the fourth consecutive year for this achievement by the ... Third Order of St. Francis . , Health data security and patient engagement are ...
(Date:7/30/2015)... , ... July 30, 2015 , ... In a meaningful ... at Serenity Palms Drug Addiction Treatment Center have created an addiction graveyard. Sharing this ... of its most beloved residents, Rocky Hudson . Hudson (1945-2015) fell in love ...
Breaking Medicine News(10 mins):Health News:Heels & Wheels for Megan's House Set for Saturday August 22, 2015 in Waycross, Georgia 2Health News:Oravan Sleep Apnea Device Gains Traction in Sleep Industry 2Health News:Manatee County’s Opioid Task Force Calls for More Funding and Face to Face Counseling After Overdose 2Health News:Manatee County’s Opioid Task Force Calls for More Funding and Face to Face Counseling After Overdose 3Health News:OSF HealthCare Named One of the Most Wired Systems 2Health News:OSF HealthCare Named One of the Most Wired Systems 3Health News:Serenity Palms Honors Rocky Hudson, an Advocate of AA and a Beloved Resident of Palm Springs 2Health News:Serenity Palms Honors Rocky Hudson, an Advocate of AA and a Beloved Resident of Palm Springs 3
... used the American Heart Association's online heart disease education ... patients, researchers reported at the American Heart Association's 8th ... Research in Cardiovascular Disease and Stroke. ,Those ... Internet-based education program developed with Thomson Healthcare also ...
... have intensified monitoring of over 800 poultry farms in the ... farms there, an official said Saturday. ... farms May 22 and in two other farms the next ... reported, quoting Livestock Commissioner R.H Usmani. ,Several thousand ...
... exercise is too much for a person, say mental health ... say that people who exercise frequently because they enjoy it, ... reason in mind, but those participating in physical activities due ... a risk of developing an exercise disorder. ,"There ...
... Asia and Australia, viewing the Blue Moon will be possible after ... assert that when two full Moons occur within a calendar month, ... ,For example, if you live London, you will officially have ... blue. ,According to astronomers and cosmologists, May 31 will ...
... enjoying parental bliss to the fullest. ,In a ... his heart out about the delight and joys of parenthood. ... Get ready to change no end of dirty diapers. I love ... to me,' the Mirror quoted Pitt, as saying. ,Meanwhile ...
... at Cambridge University in the UK have discovered mutations ... a significant role in triggering breast cancer in women ... methods of targeting younger women at higher-than-average risk of ... mammography before they reach 50 - the age when ...
Cached Medicine News:Health News:Online Education Program Better Source of Information for Patients 2Health News:Online Education Program Better Source of Information for Patients 3Health News:Attitude Determines How Much Exercise is too Much 2Health News:Blue Moon at Midnight from June 1 2Health News:UK Scientists Identify Gene Mutations That Trigger Breast Cancer 2Health News:UK Scientists Identify Gene Mutations That Trigger Breast Cancer 3
(Date:7/31/2015)... July 31, 2015  Xencor, Inc. (NASDAQ: XNCR ... for the treatment of autoimmune diseases, asthma and allergic ... Yujiro S. Hata to its board of directors. ... and corporate development is a tremendous asset to our ... chief executive officer of Xencor. "Xencor faces a range ...
(Date:7/30/2015)... , July 30, 2015 Edwards Lifesciences Corporation ... of heart valves and hemodynamic monitoring, today announced that ... of Directors. "Bob is an ardent champion for ... true privilege to have him on Edwards, board as we ... , Edwards, chairman and CEO.  "Bob has provided a valuable ...
(Date:7/30/2015)... Calif. , July 30, 2015 IRIDEX ... will release its second quarter 2015 financial results after ...   In conjunction with the release, the Company will ... 5:00 p.m. Eastern Time on Thursday, ... the quarter and other business developments. Interested ...
Breaking Medicine Technology:Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3IRIDEX Announces Second Quarter 2015 Conference Call and Release Date 2
... Intercell AG (VSE: ICLL) today announced that effective ... Management Board as Chief Business Officer with key responsibilities ... Marketing and Sales, Corporate and Business Development, and Alliance ... the other Management Board members in helping drive forward ...
... 30 Reportlinker.com announces that a new market ... Global Optoelectronics Industry ... the worldwide markets for Optoelectronics in Millions of ... & Systems, and Optical Components. Major segments analyzed ...
Cached Medicine Technology:Intercell AG Appoints Staph Leavenworth Bakali as Chief Business Officer 2Reportlinker Adds Global Optoelectronics Industry 2Reportlinker Adds Global Optoelectronics Industry 3Reportlinker Adds Global Optoelectronics Industry 4Reportlinker Adds Global Optoelectronics Industry 5Reportlinker Adds Global Optoelectronics Industry 6Reportlinker Adds Global Optoelectronics Industry 7Reportlinker Adds Global Optoelectronics Industry 8Reportlinker Adds Global Optoelectronics Industry 9Reportlinker Adds Global Optoelectronics Industry 10Reportlinker Adds Global Optoelectronics Industry 11Reportlinker Adds Global Optoelectronics Industry 12Reportlinker Adds Global Optoelectronics Industry 13Reportlinker Adds Global Optoelectronics Industry 14Reportlinker Adds Global Optoelectronics Industry 15Reportlinker Adds Global Optoelectronics Industry 16Reportlinker Adds Global Optoelectronics Industry 17Reportlinker Adds Global Optoelectronics Industry 18Reportlinker Adds Global Optoelectronics Industry 19Reportlinker Adds Global Optoelectronics Industry 20Reportlinker Adds Global Optoelectronics Industry 21Reportlinker Adds Global Optoelectronics Industry 22Reportlinker Adds Global Optoelectronics Industry 23Reportlinker Adds Global Optoelectronics Industry 24Reportlinker Adds Global Optoelectronics Industry 25
... DiscoverySE Centrifuges. Workhorse. All in one. ... the new Sorvall Discovery 100SE Ultracentrifuge ... features come with top-of-the-line performance, powerful ... all built into the smallest, quietest, ...
... DiscoveryTMM150 SE Micro-ultra centrifuge continues to raise ... processing, now with 1,048,000 x g performance ... DiscoveryTMM150SE processes sample sizes from 0.2 ... floor footprint, brushless direct drive, very quiet ...
... the highest g-force ever. But optimal productivity ... Optima MAX combines maximum force, capacity, and ... that's worlds apart from any other system. ... enhanced efficiency, Optima takes productivity to the ...
... Efficiency, versatility, and environmental safety ... Optima LE-80 K Ultracentrifuge from ... innovative Optima centrifugation technology, the ... cost effectively provide advanced capability ...
Medicine Products: