Navigation Links
Scans spot hidden tumors in rare cancer syndrome
Date:3/18/2008

BOSTON--Researchers at Dana-Farber Cancer Institute report that full-body PET/CT scanning detected unsuspected, treatable tumors in 3 of 15 patients with Li-Fraumeni syndrome (LFS), a rare genetic cancer syndrome for which no screening tests have been recommended.

The results suggest that periodic scans in combination with physical exams might catch more tumors at a curable stage, the investigators report in the March 19 issue of the Journal of the American Medical Association. But they caution that further, larger studies are needed to determine whether PET/CT screening is beneficial in LFS patients, who are highly susceptible to a variety of cancers from an early age because of an inborn gene mutation.

We need to be cautious, and we shouldn't say that every patient with the syndrome should have a PET/CT examination," said Annick Van Den Abbeele, MD, clinical director of radiology and director of nuclear medicine/positron emission tomography (PET) at Dana-Farber. "But the study showed some interesting findings that justify a larger, international study in these patients."

PET detects cancers by tracking their abnormal appetite for sugar (glucose) compared to normal tissues, while CT (computed tomography) uses X-rays to show anatomical and structural details. Combining the two modalities in a single machine allows a patient to undergo both exams in one session; the resulting images are superimposed to reveal the precise location of suspected tumors.

LFS is a rare hereditary cancer syndrome named for the researchers who first described it, Frederick Li, MD, of Dana-Farber and Joseph Fraumeni Jr., MD, of the National Cancer Institute. In most cases, the cause is a mutation in the TP53 tumor suppressor gene that can be inherited and creates a high risk of a variety of malignancies, including sarcomas, breast cancer, leukemia, brain tumors, and many more common cancers at unusually early ages, including childhood. Among individua
'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. European directive will halt use of MRI scans; cancer diagnosis and treatment will suffer
2. PET scans can accurately detect a breast tumors response to chemotherapy
3. High-tech CT scans: not a bad choice to test for clogged arteries
4. New Computerized Scans Effective for Spotting Clogged Arteries
5. PET scans useful for some cancer treatment, but how do patients fare?
6. PET Scans Can Spot Cervical Cancers Return
7. Post-treatment PET scans can reassure cervical cancer patients
8. CT scans to determine heart disease in the emergency room
9. Obesity Keeps Patients From Needed CT Scans After Surgery
10. PET Scans Could Boost Lung Cancer Diagnosis
11. Rise in CT Scans Poses Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... ... July 07, 2015 , ... Celestix Networks, the leading provider ... VA Series virtual appliances. These virtual platforms expand the existing physical appliances ... proven to simplify the on-premises deployment of unified remote access and single sign-on ...
(Date:7/7/2015)... ... 2015 , ... Illinois cannabis cultivation centers and dispensary owners ... The Medical Cannabis Alliance of Illinois’ (MCAI) board and its members have a ... making sure patients have access to cannabis as a viable medical treatment option. ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... advanced delivery technologies and development solutions for drugs, biologics and consumer health ... Excelimmune, Inc. to access its antibody combination therapy (ACT) technology platform. The ...
(Date:7/7/2015)... (PRWEB) , ... July 07, 2015 , ... Safe Catch ... every single fish for mercury. Albertsons, Gelson’s Markets, New Leaf Community Markets, Sprouts Farmers ... tuna. , “We developed the technology to test every fish for mercury,” said Safe ...
(Date:7/7/2015)... ... 07, 2015 , ... The Immune Deficiency Foundation (IDF) launched ... using its IDF ePHR, an electronic personal health record powered by Get Real ... track their health information, including symptoms, diagnoses, medications, infusions and other critical health ...
Breaking Medicine News(10 mins):Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 2Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 3Health News:Celestix Now Offers Virtual Editions of Its Unified Remote Access and SSO Platforms to Enable Easy Deployment in Virtualized Environments 4Health News:Cannabis Growers and Dispensaries Form Medical Cannabis Alliance of Illinois 2Health News:Catalent Biologics Adds New Technology Platform to Enable Antibody Combination Therapies 2Health News:Safe Catch Launches Tuna with Lowest Mercury Limit of Any Brand 2Health News:Get Real Health Launches New Mobile App for Immune Deficiency Foundation Patient Community 2Health News:Get Real Health Launches New Mobile App for Immune Deficiency Foundation Patient Community 3
... HealthDay Reporter , WEDNESDAY, Jan. 5 (HealthDay News) ... and other symptoms of irritable bowel syndrome, a common ... ended, new research shows. Researchers say the antibiotic, ... for irritable bowel syndrome that gets at the underlying ...
... has awarded a grant of $240,000 to an international ... the effects of hip replacement therapy on the employment ... at the Universit Bocconi (Milan), the consortium also includes ... the Johns Hopkins University School of Public Health (Baltimore). ...
... Lou Gehrig,s disease, or amyotrophic lateral sclerosis (ALS), and ... in brain and spinal-cord cells that include an RNA-binding ... block of the lesions formed by these clumps. ... of Clinical Investigation , a team led by Virginia ...
... are reporting new evidence on how studded tires wintertime ... damage to pavement may also damage the health of ... metal protrusions from the rubber tread that improve traction on ... Chemical Research in Toxicology , a monthly journal. Anders ...
... While a much hailed communication intervention works for families ... care units, Case Western Reserve University researchers found the ... patients. Barbara Daly and Sara Douglas, the study,s ... Nursing at Case Western Reserve, attribute the varied results ...
... Reporter , WEDNESDAY, Jan. 5 (HealthDay News) -- The one-dose ... the United States for the first half of the past ... second study has found that the two-dose version of the ... and Prevention in 2006, may offer youngsters even better protection. ...
Cached Medicine News:Health News:Antibiotic May Help Ease Irritable Bowel 2Health News:Antibiotic May Help Ease Irritable Bowel 3Health News:International consortium to examine the impact of medical devices on health and retirement 2Health News:International consortium to examine the impact of medical devices on health and retirement 3Health News:Malfunctioning gene associated with Lou Gehrig's disease leads to nerve-cell death in mice 2Health News:ICU communication study reveals complexities of family decision-making 2Health News:ICU communication study reveals complexities of family decision-making 3Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 2Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 3Health News:Chickenpox Vaccine Cuts Hospitalization Rates: Study 4
(Date:7/7/2015)... July 7, 2015   Decision Resources Group ... in dialysis patient management in the U.S. versus ... by U.S. and EU5 nephrologists from approximately 1,870 ... are the most commonly used renal medications in ... differs considerably between the two regions.      ...
(Date:7/7/2015)... FRANCISCO , July 7, 2015 ... reach USD 1,197.7 million by 2020, growing at an estimated ... new study by Grand View Research, Inc. Introduction of innovative ... coupled with growing awareness levels pertaining to the advantages of ... the next six years. In addition, presence of untapped growth ...
(Date:7/7/2015)... , July 7, 2015 EnteroMedics Inc. ... devices that use neuroblocking technology to treat obesity, metabolic ... its previously announced public offering of 32,000,000 units. Each unit ... Series A warrant to purchase one share of common ... Investors whose purchase of units in the offering would ...
Breaking Medicine Technology:Similarities And Differences Exist When Comparing U.S. Versus EU5 Dialysis Patient Management 2Similarities And Differences Exist When Comparing U.S. Versus EU5 Dialysis Patient Management 3Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 2Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 3Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 4EnteroMedics Inc. Announces Pricing of $16.0 Million Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Pricing of $16.0 Million Public Offering of Common Stock and Warrants 3
... CHICAGO and ORANGE, Calif., Feb. 23, 2011 ... (SJHS), a $4.6 billion not-for-profit Catholic healthcare system based in ... in California, West Texas and Eastern New Mexico, has selected ... MDRX ) to streamline patient movement through their ...
... Caliper Life Sciences, Inc. (Nasdaq: ... announced a co-marketing agreement which will leverage Covaris, ... microfluidics technologies to develop automated workflows for next ... suite of solutions for library construction, sample analysis, ...
Cached Medicine Technology:St. Joseph Health System Selects Allscripts Care Management and Homecare Solutions 2St. Joseph Health System Selects Allscripts Care Management and Homecare Solutions 3St. Joseph Health System Selects Allscripts Care Management and Homecare Solutions 4St. Joseph Health System Selects Allscripts Care Management and Homecare Solutions 5Caliper and Covaris Establish Co-Marketing Agreement to Simplify Next Generation Sequencing 2Caliper and Covaris Establish Co-Marketing Agreement to Simplify Next Generation Sequencing 3
... Practice management software for ... a true multi-tasking, multi-office practice ... in database technology- Winx Pro ... will assist you in effectively ...
The XT-1800i is a compact, high performance, automated hematology analyzer that provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test re...
The SE-9000 automated hematology analyzer provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test results for enhanced screening ability....
... offers three-dimensional VCS technology, ... and efficiency in white ... analysis. With its reputation ... HmX is an affordable ...
Medicine Products: