Navigation Links
Scan Technology Tied to Overtreatment of Clots in Lungs

MONDAY, May 9 (HealthDay News) -- Overdiagnosis and overtreatment of pulmonary embolism is a problem in the United States due to the large increase in the use of computed tomography pulmonary angiography (CTPA), a new study suggests.

A pulmonary embolism (PE) is a potentially life-threatening blood clot in the lungs. CTPA was introduced in 1998 to improve detection of PE and its use has grown rapidly, according to background information in the study by Boston University School of Medicine researchers.

The investigators compared data about PE in U.S. adults before (1993-1998) and after (1998-2006) CTPA was introduced, and found that the incidence of PE increased 81 percent after CTPA became available, from 62.1 to 112.3 per 100,000 people.

Deaths from PE decreased during both time periods, but more so before (8 percent reduction, from 13.4 to 12.3 per 100,000), than after the introduction of CTPA (3 percent reduction, from 12.3 to 11.9 per 100,000 people), the research team reported.

There was also a slight improvement in case fatality before CTPA (8 percent decrease, from 13.2 to 12.1 percent of patients) and a substantial improvement after CTPA (36 percent decrease, from 12.1 to 7.8 percent of cases), according to the report published in the May 9 issue of the Archives of Internal Medicine.

While CTPA offers many benefits, the downside is that it can detect clots so small that they might never cause symptoms or death, yet the treatment for these clots, known as anti-clotting therapy, may be harmful to patients, the researchers said.

"Overdiagnosis matters because it can lead to [treatment-related] harm. While a clinically insignificant PE is by definition not harmful, treating such an embolism can cause harm such as bleeding from anticoagulation [anti-clotting therapy], which can -- in the worst case -- be fatal," lead author Dr. Renda Soylemez Wiener, an assistant professor of medicine, said in a university news release.

The frequency of presumed complications of anticoagulation for PE was stable before CTPA, but increased 71 percent (from 3.1 to 5.3 per 100,000) after CTPA became available, the study authors explained.

The problem of overdiagnosis and overtreatment of PE is likely to continue to grow, according to the study authors. They called for further research to determine whether some PE patients with small clots can safely forgo anticoagulation treatment.

More information

The Society for Vascular Surgery has more about pulmonary embolism.

-- Robert Preidt

SOURCE: Boston University Medical Center, news release, May 9, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Three NHS Trusts Choose BigHand Voice Technology Under YHCPC Framework Agreement
2. Gold at Forefront of Nanotechnology Revolution
3. Human Dental Technology Leads to Breakthroughs for Pet Dental Health at Sergeants Pet Care Products, Inc.
4. Embark Health Selects the Jellyvision Lab's Interactive Conversation Technology to Educate Website Visitors on Advance Directives
5. First Breakthrough in Water Heating Technology!
6. New Technology Could Widen Reach of Vaccines
7. WebMD to Present at the Goldman Sachs Technology and Internet Conference 2010
8. Nanotechnology could help Arab region
9. Genetic health risks in children of assisted reproductive technology
10. Mennen Medical Launches the VitaLogik 6000, a Pre-Configured Multi-Parameter Patient Monitor with New High Performance Wireless Technology
11. New cardiac CT technology drastically reduces patient radiation exposure
Post Your Comments:
Related Image:
Scan Technology Tied to Overtreatment of Clots in Lungs
(Date:6/25/2016)... ... 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can ... CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn ... X . Simply select a ProHand generator and drag it above media or text ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Scientific Sessions in Dallas that it will receive two significant new grants to ... came as PHA marked its 25th anniversary by recognizing patients, medical professionals and ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the ... as Vice President of North American Capital Sales at HTG Molecular . ... team in the commercialization of the HTG EdgeSeq system and associated reagents in North ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ... Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) expired ... Time). As previously announced on May 31, ... merger agreement under which Jazz Pharmaceuticals has commenced a ...
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... , June 24, 2016 ... of the "Structural Electronics 2015-2025: Applications, Technologies, ... In-Mold Electronics, Smart Skin, ... Photovoltaics Structural electronics involves electronic ... load-bearing, protective structures, replacing dumb structures such as ...
Breaking Medicine Technology: