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Sanofi-aventis Delivers 2008 Results Above Guidance
Date:2/11/2009

ion. Sanofi Pasteur MSD reached 2008 full-year sales of EUR 1,272 million, an increase of 21.8% on a reported basis. Full-year net sales of Gardasil(R) were EUR 584 million, compared with EUR 342 million in 2007.

Net sales by geographic region

    EUR million                 Q4 2008   Change on a  FY 2008  Change on a
                                  net       comparable   net    comparable
                                 sales        basis     sales       basis

    Europe                        3,006        -2.2%    12,096        -0.6%
    United States                 2,244        +7.2%     8,609        +5.4%
    Other Countries               1,839        +9.8%     6,863       +10.1%
    TOTAL                         7,089         3.6%    27,568         3.7%

During 2008, sales in France and Germany weighed on net sales in Europe, which fell slightly (by 0.6%). The generifications(4) of Eloxatin(R) (especially in France) pared around 1.3 points of growth in Europe. Since August 2008, sales of Plavix(R) in Germany have been affected by competition from several clopidogrel besylates in certain indications.

In the United States, sales growth resumed at a healthier pace in the last two quarters of 2008 after having been hampered by competition from generics of Ambien IR(R) in the first part of the year, due to particularly excellent performances from Lantus(R) and Taxotere(R). Generics of Ambien IR(R)(5) cost 4.6 points of sales growth over 2008 as a whole.

Net sales in the "Other Countries" region during 2008 were lifted by a particularly strong performance in Japan (up 18.5% at EUR 1,408 million), driven by the success of Plavix(R) (net sales reached EUR 182 million in 2008 vs. EUR 66 million in 2007 and Myslee(R) (net sales reached EUR 142 million in 2008, up 14.9%)

(4) Excluding net sales of Eloxatin(R) in Europe in 20
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SOURCE sanofi-aventis
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