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Sanofi-aventis Announces a Good Third Quarter Performance; Increase in 2007 full-year earnings growth guidance
Date:10/31/2007

0 patients. The new development program in diabetes, essentially as an add-on to the main existing treatments (metformin, sulfonylurea and insulin), includes a comparative study with sitagliptin, the most recently approved treatment. Submission in type 2 diabetes is expected in 2009, while submission of a fixed rimonabant/metformin combination is expected in 2010.

Xyzal(R), a new once-daily prescription oral antihistamine used to treat internal and external allergies and chronic idiopathic urticaria, was launched in the United States by sanofi-aventis and UCB at the start of October. The product, which has been shown to be highly effective in the treatment of allergy symptoms, is indicated for adults and for children aged six and over.

Worldwide presence(1) of Plavix(R) / Iscover(R)

Change on Change on

a a

2007 comparable 2007 comparable

euro million Q3 basis 9 months basis

Europe 450 +6.6% 1,350 +5.4%

United States 797 +126.4% 2,159 +23.9%

Other countries 213 +23.8% 601 +21.2%

TOTAL 1,460 +54.3% 4,110 +16.8%

On June 19, 2007, the U.S. District Court for the Southern District of New York upheld the validity and enforceability of the U.S. patent covering clopidogrel bisulfate, the active ingredient of Plavix(R), and issued a permanent injunction enjoining Apotex from marketing its generic clopidogrel bisulfate in the United States prior to the expiration of the patent. Apotex launched a generic clopidogrel bisulfate in August 2006, following which the U.S. District Court for the Southern District of New York awarded sanofi- aventis a temporary injunction on August 31,
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SOURCE sanofi-aventis
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