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Sanofi-aventis Announces a Good Third Quarter Performance; Increase in 2007 full-year earnings growth guidance
Date:10/31/2007

Change on

a a

2007 comparable 2007 comparable

euro million Q3 basis 9 months basis

Europe 229 +6.5% 689 +6.3%

United States 128 +8.5% 378 +8.3%

Other countries 105 +12.9% 304 +17.4%

TOTAL 462 +8.5% 1,371 +9.2%

Third-quarter worldwide sales of Aprovel(R)/Avapro(R)/Karvea(R) were up 8.5% at euro 462 million.

In the United States, the product achieved third-quarter net sales growth of 8.5%.

On April 18, the Cardio-Renal Advisory Committee of the FDA recommended approval of Avalide(R) as an initial treatment for hypertension. Avalide(R) is a fixed-dose combination of irbesartan and hydrochlorothiazide that is currently approved for the treatment of hypertension in patients with blood pressure uncontrolled on monotherapy. If approved, the new indication for Avalide(R) would be the first-line treatment for hypertension in patients who are unlikely to obtain their blood pressure goals on monotherapy.

Net sales by business segment -- Human Vaccines

Third-quarter consolidated net sales for the Human Vaccines business were up 49.2% at euro 943 million.

The period was boosted by earlier shipments of influenza vaccines than in 2006, when a substantial proportion of shipments were postponed to the final quarter. As a result, net sales of influenza vaccines rose by 117.3% in the quarter to euro 365 million.

Adacel(TM) (adult and adolescent tetanus-diphtheria-pertussis booster) and Menactra(R) also performed very strongly in the third quarter, with net sales up 75.9% at euro 77 million and up 124.9% at euro 165 million respectively.

In October, the FDA extended the license for Menactra(R
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SOURCE sanofi-aventis
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