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Sanofi-aventis Announces Good First-quarter 2009 Performance
Date:4/29/2009

ond half of 2008. In the United States, the product posted 2.9% growth in net sales to euro 197 million.

Net sales of Eloxatin(R), the leading cytotoxic agent in the colorectal cancer market as an adjuvant and as first line treatment in the metastatic phase, were up 3.0% at euro 266 million in the United States, where growth for the product continues to be driven mainly by its indication as an adjuvant in colorectal cancer. In Europe, sales of the product continued to fall due to competition from generics, with net sales for the quarter totaling euro 31 million.

Worldwide presence of Plavix(R)/Iscover(R)

In the United States, sales of Plavix(R), which are consolidated by Bristol Myers Squibb (BMS), recorded strong growth of 13.6%. In Europe, sales held steady despite competition from clopidogrel besylate in the monotherapy segment in Germany, where Plavix(R)/Iscover(R) still had volume market share of around 70% in March 2009 (IMS Pharmatrend: week ending March 27, 2009). The success enjoyed by Plavix(R) in Japan continued, with net sales up 90.2% at euro 70 million.

    euro  million                            Q1 2009       Change
    Europe                                       446        +0.2%
    United States                                987       +13.6%
    Other Countries                              266        +8.2%
    TOTAL                                      1,699        +8.6%

On March 31, 2009, findings from the ACTIVE-A study were presented at the American College of Cardiology Scientific Sessions. The findings demonstrated that for patients with atrial fibrillation who were at increased risk of stroke and could not take oral anticoagulant medication, Plavix(R) plus aspirin significantly reduced major vascular events by 11% over aspirin (6.8% vs. 7.6%, per year, p=0.01). The greatest
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SOURCE Sanofi-aventis
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