Navigation Links
Sandalwood scent facilitates wound healing and skin regeneration
Date:7/8/2014

Skin cells possess an olfactory receptor for sandalwood scent, as researchers at the Ruhr-Universitt Bochum have discovered. Their data indicate that the cell proliferation increases and wound healing improves if those receptors are activated. This mechanism constitutes a possible starting point for new drugs and cosmetics. The team headed by Dr Daniela Busse and Prof Dr Dr Dr med habil Hanns Hatt from the Department for Cellphysiology published their report in the "Journal of Investigative Dermatology".

The nose is not the only place where olfactory receptors occur

Humans have approximately 350 different types of olfactory receptors in the nose. The function of those receptors has also been shown to exist in, for example spermatozoa, the prostate, the intestine and the kidneys. The team from Bochum has now discovered them in keratinocytes cells that form the outermost layer of the skin.

Experiments with cultures of human skin cells

The RUB researchers studied the olfactory receptor that occurs in the skin, namely OR2AT4, and discovered that it is activated by a synthetic sandalwood scent, so-called Sandalore. Sandalwood aroma is frequently used in incense sticks and is a popular component in perfumes. The activated OR2AT4 receptor triggers a calcium-dependent signal pathway. That pathway ensures an increased proliferation and a quicker migration of skin cells processes which typically facilitate wound healing. In collaboration with the Dermatology Department at the University of Mnster, the cell physiologists from Bochum demonstrated that effect in skin cell cultures and skin explants.

Additional olfactory receptors in skin detected

In addition to OR2AT4, the RUB scientists have also found a variety of other olfactory receptors in the skin, the function of which they are planning to characterise more precisely. "The results so far show that they possess therapeutic and cosmetic potential," says Prof Hanns Hatt. "Still, we mustn't forget that concentrated fragrances should be handled with care, until we have ascertained which functions the different types of olfactory receptors in skin cells have."


'/>"/>

Contact: Dr. Hanns Hatt
Hanns.Hatt@rub.de
49-234-322-4586
Ruhr-University Bochum
Source:Eurekalert

Related medicine news :

1. One in six adolescents in the ER has experienced dating violence
2. Case Western Reserve, University Hospitals fundraising for adolescent, young adult cancer
3. Malaria parasite manipulates hosts scent
4. 12 minutes of exercise improves attention, reading comprehension in low-income adolescents
5. Having authoritarian parents increases the risk of drug use in adolescents
6. Higher discharge rate for BPD in children and adolescents in the US compared to UK
7. New technology using florescent proteins tracks cancer cells circulating in the blood
8. Coached extracurricular activities may help prevent pre-adolescent smoking and drinking
9. Study: Altruistic adolescents less likely to become depressed
10. RI Hospital physician: Legalizing medical marijuana doesnt increase use among adolescents
11. NUS researchers developed worlds first fluorescent sensor to detect date rape drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson ... Recently, he has implemented orthobiologic procedures as a method for treating his patients. ... the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... TX (PRWEB) , ... June 24, 2016 , ... People ... part in Genome magazine’s Code Talker Award, an essay contest in which patients and ... an award to be presented at the 2016 National Society of Genetic Counselors (NSGC) ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
Breaking Medicine Technology: