Navigation Links
Sandalwood scent facilitates wound healing and skin regeneration
Date:7/8/2014

Skin cells possess an olfactory receptor for sandalwood scent, as researchers at the Ruhr-Universitt Bochum have discovered. Their data indicate that the cell proliferation increases and wound healing improves if those receptors are activated. This mechanism constitutes a possible starting point for new drugs and cosmetics. The team headed by Dr Daniela Busse and Prof Dr Dr Dr med habil Hanns Hatt from the Department for Cellphysiology published their report in the "Journal of Investigative Dermatology".

The nose is not the only place where olfactory receptors occur

Humans have approximately 350 different types of olfactory receptors in the nose. The function of those receptors has also been shown to exist in, for example spermatozoa, the prostate, the intestine and the kidneys. The team from Bochum has now discovered them in keratinocytes cells that form the outermost layer of the skin.

Experiments with cultures of human skin cells

The RUB researchers studied the olfactory receptor that occurs in the skin, namely OR2AT4, and discovered that it is activated by a synthetic sandalwood scent, so-called Sandalore. Sandalwood aroma is frequently used in incense sticks and is a popular component in perfumes. The activated OR2AT4 receptor triggers a calcium-dependent signal pathway. That pathway ensures an increased proliferation and a quicker migration of skin cells processes which typically facilitate wound healing. In collaboration with the Dermatology Department at the University of Mnster, the cell physiologists from Bochum demonstrated that effect in skin cell cultures and skin explants.

Additional olfactory receptors in skin detected

In addition to OR2AT4, the RUB scientists have also found a variety of other olfactory receptors in the skin, the function of which they are planning to characterise more precisely. "The results so far show that they possess therapeutic and cosmetic potential," says Prof Hanns Hatt. "Still, we mustn't forget that concentrated fragrances should be handled with care, until we have ascertained which functions the different types of olfactory receptors in skin cells have."


'/>"/>

Contact: Dr. Hanns Hatt
Hanns.Hatt@rub.de
49-234-322-4586
Ruhr-University Bochum
Source:Eurekalert

Related medicine news :

1. One in six adolescents in the ER has experienced dating violence
2. Case Western Reserve, University Hospitals fundraising for adolescent, young adult cancer
3. Malaria parasite manipulates hosts scent
4. 12 minutes of exercise improves attention, reading comprehension in low-income adolescents
5. Having authoritarian parents increases the risk of drug use in adolescents
6. Higher discharge rate for BPD in children and adolescents in the US compared to UK
7. New technology using florescent proteins tracks cancer cells circulating in the blood
8. Coached extracurricular activities may help prevent pre-adolescent smoking and drinking
9. Study: Altruistic adolescents less likely to become depressed
10. RI Hospital physician: Legalizing medical marijuana doesnt increase use among adolescents
11. NUS researchers developed worlds first fluorescent sensor to detect date rape drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... On June ... sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, ... of the city’s history as home to some of the world’s leading providers of ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... San Francisco, CA (PRWEB) , ... June 24, ... ... at CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has ... , self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
Breaking Medicine Technology: