Navigation Links
Saltier intravenous fluids reduce complications from surgery
Date:7/15/2014

(PHILADELPHIA) -- Adequate hydration via a saline drip is essential during surgery, but recent reports suggest that getting the balance of salt and water just right could have an important impact on patient recovery. In the largest study of its kind researchers at Thomas Jefferson University found that a slightly saltier intravenous drip (hypertonic saline), and lower total volume of fluid received, reduced the overall rate of complications by 25 percent after the complex Whipple surgery for pancreatic cancer.

"This relatively minor change in intravenous fluids has had a tremendous effect on the overall complication rate for our patients," says first author Harish Lavu, M.D., Associate Professor of Surgery at Thomas Jefferson University. "Based on these findings we have already changed our practice in the operating room to use hypertonic saline," he added.

Saline delivered intravenously during and after surgery helps to maintain a patient's fluid balance and blood pressure within the appropriate range. The increased salt concentration in the hypertonic saline is designed to keep the body in equilibrium by helping to reduce fluid buildup in the lungs, interstitial spaces and swelling in the extremities.

The hypertonic saline draws out the excess fluid that builds up in these tissues. "Too much swelling can compromise the delivery of blood and oxygen to the organs. That reduction can slow the healing process," says Dr. Lavu.

The current study is the largest of its kind and shows a benefit when hypertonic saline is used for the Whipple operation, which can take from to 5-9 hours to perform. Patients undergoing this operation for pancreatic cancer can have complications such as blood clots, pneumonia, wound infection, urinary tract infections, and others.

A total of 264 patients were enrolled in the study, with 128 receiving standard fluid and 131 receiving a hypertonic saline solution. By examining all of the complications together, the researchers found a 25 percent reduction in overall complications in the group that received hypertonic saline. In absolute numbers, 93 patients in the hypertonic group had complications, compared with 123 patients in the standard fluid group.

"We are confident that this change in our surgical process will help our patients recover faster with fewer complications," says senior author Charles J. Yeo, M.D., The Samuel D. Gross Professor and Chair of the Department of Surgery at Thomas Jefferson University.


'/>"/>
Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Fast Food Is Saltier in U.S. Than Overseas
2. Global Intravenous Solutions (Parenteral Nutrition) Industry
3. Global Intravenous Immunoglobulin (IVIg) Industry
4. Drilling Fluids & Completion Fluids Market (Water-Based Systems, Oil-Based Systems, Synthetic-Based Systems) Worth $15.0 Billion by 2018 - New Report by MarketsandMarkes
5. Clues to cocaines toxicity could lead to better tests for its detection in biofluids
6. Huntingtons Disease Linked to Reduced Cancer Risk in Study
7. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
8. Decision guide reduced uncertainty over breast cancer prevention, study finds
9. Scoliosis Treatment Might Reduce Need for Surgeries
10. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
11. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... , ... February 05, 2016 , ... The American public ... such water may be safer than regular municipal or well water. The recent experience ... host Sharon Kleyne, could go a long way toward increasing public acceptance of recycled ...
(Date:2/5/2016)... Dallas, Texas (PRWEB) , ... February 05, 2016 , ... ... to allow users to search for and donate to Give To Cure’s campaign ... is an app that lets users make and share payments through a smart device. ...
(Date:2/5/2016)... ... February 05, 2016 , ... Pivot Point Consulting, ... in KLAS: Software & Services for HIT Implementation Support & Staffing report with ... ranks vendor performance by healthcare executives, managers and clinicians representing over 4,500 hospitals ...
(Date:2/5/2016)... ... February 05, 2016 , ... Dr. Justin Scott and Dr. Lydia Muccioli of ... Dental Day to individuals in need. The event is scheduled to take place on ... Day is to provide dental care to community members in need. Each patient will ...
(Date:2/5/2016)... , ... February 05, 2016 , ... ... of CitiDent, announces that it is now welcoming orthodontist, Dr. Amanda Cheng, ... offers a complete range of oral health care, including general dentistry, cosmetic treatments, ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016 For hospitals considering ... those already participating in the program, the Health Resources ... to as the , Mega-Guidance , could have significant ... is published in September 2016. Essential Insights ... Service Marketing , summarizes the Mega-Guidance,s key proposed changes, ...
(Date:2/4/2016)... Feb. 4, 2016  The Senior Care Pharmacy ... Reform Committee Chairman Jason Chaffetz (R-UT) ... today,s hearing , "Developments in the Prescription ... and growing questions about abusive pharmacy benefit manager ... (R-UT) and Ranking Member Elijah Cummings (D-MD) are ...
(Date:2/4/2016)... Bernstein Liebhard LLP today announced that a securities class ... for the District of Arizona on ... or entities who purchased common shares of Insys Therapeutics Inc. ... 3, 2015 through January 25, 2016 (the "Class Period").  The ... of the Securities Exchange Act of 1934.  ...
Breaking Medicine Technology: