Navigation Links
Saltier intravenous fluids reduce complications from surgery
Date:7/15/2014

(PHILADELPHIA) -- Adequate hydration via a saline drip is essential during surgery, but recent reports suggest that getting the balance of salt and water just right could have an important impact on patient recovery. In the largest study of its kind researchers at Thomas Jefferson University found that a slightly saltier intravenous drip (hypertonic saline), and lower total volume of fluid received, reduced the overall rate of complications by 25 percent after the complex Whipple surgery for pancreatic cancer.

"This relatively minor change in intravenous fluids has had a tremendous effect on the overall complication rate for our patients," says first author Harish Lavu, M.D., Associate Professor of Surgery at Thomas Jefferson University. "Based on these findings we have already changed our practice in the operating room to use hypertonic saline," he added.

Saline delivered intravenously during and after surgery helps to maintain a patient's fluid balance and blood pressure within the appropriate range. The increased salt concentration in the hypertonic saline is designed to keep the body in equilibrium by helping to reduce fluid buildup in the lungs, interstitial spaces and swelling in the extremities.

The hypertonic saline draws out the excess fluid that builds up in these tissues. "Too much swelling can compromise the delivery of blood and oxygen to the organs. That reduction can slow the healing process," says Dr. Lavu.

The current study is the largest of its kind and shows a benefit when hypertonic saline is used for the Whipple operation, which can take from to 5-9 hours to perform. Patients undergoing this operation for pancreatic cancer can have complications such as blood clots, pneumonia, wound infection, urinary tract infections, and others.

A total of 264 patients were enrolled in the study, with 128 receiving standard fluid and 131 receiving a hypertonic saline solution. By examining all of the complications together, the researchers found a 25 percent reduction in overall complications in the group that received hypertonic saline. In absolute numbers, 93 patients in the hypertonic group had complications, compared with 123 patients in the standard fluid group.

"We are confident that this change in our surgical process will help our patients recover faster with fewer complications," says senior author Charles J. Yeo, M.D., The Samuel D. Gross Professor and Chair of the Department of Surgery at Thomas Jefferson University.


'/>"/>
Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Fast Food Is Saltier in U.S. Than Overseas
2. Global Intravenous Solutions (Parenteral Nutrition) Industry
3. Global Intravenous Immunoglobulin (IVIg) Industry
4. Drilling Fluids & Completion Fluids Market (Water-Based Systems, Oil-Based Systems, Synthetic-Based Systems) Worth $15.0 Billion by 2018 - New Report by MarketsandMarkes
5. Clues to cocaines toxicity could lead to better tests for its detection in biofluids
6. Huntingtons Disease Linked to Reduced Cancer Risk in Study
7. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
8. Decision guide reduced uncertainty over breast cancer prevention, study finds
9. Scoliosis Treatment Might Reduce Need for Surgeries
10. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
11. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... CA & CARMEL, IN (PRWEB) , ... August 18, 2017 , ... ... on its 36th annual list, the most prestigious ranking of the nation's fastest-growing private ... been included in the exclusive Inc. 5000 ranking . This year’s ranking reflects ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Three Narrow Roads”: a vivid and ... of published author, Rev. Dr. Burnett King Sr., is currently the pastor-teacher-visionary at Simply ... the Faith Track Club, Inc., a track-and-field program geared towards youth. , King shares, ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Kingdom Mandate for Kingdom Builders”: ... “Kingdom Mandate for Kingdom Builders” is the creation of published author, John F. ... Eastern Europe as a missionary in 1983. He spent three decades training pastors ...
(Date:8/17/2017)... ... August 17, 2017 , ... Riccobene Associates ... location in Goldsboro, NC to its family of practices. Residents of Goldsboro will ... starting August 15, 2017. , Riccobene Associates Family Dentistry, founded by Dr. ...
(Date:8/17/2017)... MA (PRWEB) , ... August 17, 2017 , ... ... will come together on September 19, 2017 for Anti-Infectives Rx. This off-the-record networking ... B. Martin Conference Center at Harvard Medical School. , Industry leaders and decision ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... 7, 2017 Zimmer Biomet Holdings, Inc. (NYSE and ... that its Board of Directors has approved the payment of ... of 2017. The cash ... about October 27, 2017 to stockholders of record as of ... of dividends are subject to approval of the Board of ...
(Date:8/4/2017)... -- Agragen, LLC, a Cincinnati -based ... and aquacultural feed sectors, announces a significant step ... AGR131.  This drug is designed to trap and ... patients suffering from inflammatory conditions such as rheumatoid ... Biological pharmaceuticals currently used ...
(Date:8/2/2017)... , Aug. 2, 2017 CaryRx, a next-generation full-service ... delivery service for patients in the Washington D.C. ... retail pharmacy by providing delivery of medications through the convenience ... future delivery or delivered within one hour to any location ... excited to bring this invaluable service to Washington ...
Breaking Medicine Technology: