Navigation Links
Salmonella spreads by targeting cells in our gut, study shows
Date:12/11/2012

Researchers have found that the bacteria are able to change key cells that line the intestine, enabling the bugs to thrive.

By changing the make-up of these cells, the salmonella bacteria are able to cross the gut wall and infect vital organs, such as the kidneys and the liver.

Salmonella food poisoning commonly caused by eating undercooked poultry or eggs can lead to diarrhoea, fever and even death in young children.

Scientists say the study furthers our understanding of how bacterial infections occur and what enables them to spread.

The University of Edinburgh research found that the salmonella released a protein SopB changing the make-up of certain cells that line the gut. This causes a dramatic increase in cells called microfold or M cells.

The work, published in Cell Host & Microbe, reveals how once the salmonella produces large number of these cells it can then get through into the bloodstream, causing infection.

Lead researcher Dr Arvind Mahajan, from The Roslin Institute at the University of Edinburgh, said: "Bacteria have evolved sophisticated strategies to interact with and infect the host. This highlights yet another way in which microbes are able to transform cells into a type that suits their habitat."


'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

Page: 1

Related medicine news :

1. Health Officials Tracking Salmonella Outbreak Linked to Pet Turtles
2. FDA Cites Possible Source of Cantaloupe-Salmonella Outbreak
3. 33 Sickened by Salmonella Linked to Ground Beef: CDC
4. Ohio Mail-Order Hatchery Now Linked to Salmonella in 23 States
5. Scientists discover how stomach cancer spreads
6. PawnUp.com Online Pawn Shop Spreads Awareness About its Small Business Loans.
7. Targeting neurotransmitter may help treat gastrointestinal conditions
8. Targeting downstream proteins in cancer-causing pathway shows promise in cell, animal model
9. Targeting inflammation to treat depression
10. Targeting inflammation to prevent, treat cancers
11. New targeting technology improves outcomes for patients with atrial fibrillation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: