Navigation Links
Salk scientists discover previously unknown requirement for brain development
Date:6/21/2013

Scientists at the Salk Institute for Biological Studies have demonstrated that sensory regions in the brain develop in a fundamentally different way than previously thought, a finding that may yield new insights into visual and neural disorders.

In a paper published June 7, in Science, Salk researcher Dennis O'Leary and his colleagues have shown that genes alone do not determine how the cerebral cortex grows into separate functional areas. Instead, they show that input from the thalamus, the main switching station in the brain for sensory information, is crucially required.

O'Leary has done pioneering studies in "arealization," the way in which the neo-cortex, the major region of cerebral cortex, develops specific areas dedicated to particular functions. In a landmark paper published in Science in 2000, he showed that two regulatory genes were critically responsible for the general pattern of the neo-cortex, and has since shown distinct roles for other genes in this process. In this new set of mouse experiments, his laboratory focused on the visual system, and discovered a new, unexpected twist to the story.

"In order to function properly, it is essential that cortical areas are mapped out correctly, and it is this architecture that was thought to be genetically pre-programmed," says O'Leary, holder of the Vincent J. Coates Chair in Molecular Neurobiology at Salk. "To our surprise, we discovered thalamic input plays an essential role far earlier in brain development."

Vision is relayed from the outside world into processing areas within the brain. The relay starts when light hits the retina, a thin strip of cells at the back of the eye that detects color and light levels and encodes the information as electrical and chemical signals. Through retinal ganglion cells, those signals are then sent into the Lateral Geniculate Nucleus (LGN), a structure in thalamus.

In the next important step in the relay, the
'/>"/>

Contact: Kat Kearney
kkearney@salk.edu
619-296-8455
Salk Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists catch EGFR passing a crucial message to cancer-promoting protein
2. Scientists at UMass Medical School identify neurons that control feeding behavior in Drosophila
3. Scientists ID Gene Behind Early Onset Puberty
4. NIH scientists discover how HIV kills immune cells
5. Scientists find potential new clues for identifying breast cancer risk
6. PolyU Scientists Help Identify Genes Causing Myopia
7. Scientists Gauge Radiation Dose From Trip to Mars
8. Scientists Spot Genes Tied to Success at School, College
9. German and Israeli scientists gain new insights into protein disposal
10. Scientists Cant Replicate Surprising Finding on Alzheimers Treatment
11. Scientists discover how rapamycin slows cell growth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... 2014 The Delta Dental Community Care ... National Children’s Oral Health Foundation: America’s ToothFairy (NCOHF) to ... County Oral Health Zone Program® in California. , The ... a range of local constituent groups and stakeholders in ... tooth decay and its devastating effects on local families. ...
(Date:9/17/2014)... diabetes, quitting smoking, controlling high blood pressure, exercising and ... dementia -- even late in life, according to new ... by Alzheimer,s Disease International, revealed that diabetes can increase ... noted that obesity and an inactive lifestyle are key ... pressure. The researchers suggested that dementia should ...
(Date:9/17/2014)... not properly designed to meet the needs of patients ... families, and major changes to the system are necessary, ... The 21-member committee that wrote the report envisioned ... care and social services and that is high-quality, affordable, ... care planning" for end-of-life by individuals, for improved training ...
(Date:9/17/2014)... most 18-month-olds learn an average of two to five ... how children process information to learn new words as ... study, a University of Missouri researcher has found that ... limit exists as to how many words they can ... their children,s vocabularies and assist speech-language professionals in developing ...
(Date:9/17/2014)... 17, 2014 CarePoint Health became the ... 150 CarePoint Health employees participated in the Ice Bucket ... Association. The event took place on September 9, ... CarePoint Health donated $100 to the ALS Association for ... total of approximately $15,000. The Ice Bucket Challenge was ...
Breaking Medicine News(10 mins):Health News:Delta Dental Community Care Foundation Donation to America's ToothFairy Helps Deliver Critical Services 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 3Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 2Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 3Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 4Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 5Health News:Babies learn words differently as they age, researcher finds 2Health News:CarePoint Health Accepts the Ice Bucket Challenge 2Health News:CarePoint Health Accepts the Ice Bucket Challenge 3
... reveals that virgin olive oil is the best among vegetable ... the Annals of Internal Medicine.// It says heart disease risk ... first pressing of olives gives virgin olive oil. Refined oil ... polyphenols than the latter. ,The study was conducted ...
... intelligent ways to conquer the ubiquitous problem of the bulge, ... protein rich diet vis a vis carbohydrate or fat laden ... of fewer calories that wards off obesity. ... the quantity of peptide YY (PYY), a hormone that actually ...
... situation can play an important role in inspiring memory. ... conducting a more in-depth research// on the formation of ... very anticipation of a fearful situation can stir up ... event has occurred. ,The researchers explained that ...
... women patients who wish to preserve their modesty for religious ... in Lancashire have asked a Calderdale firm is to make ... patients for protection of their religious beliefs. ... considered the first of its kind to be introduced in ...
... have a decreased risk of developing diabetes, according to ... The study found that// only 8 percent of the ... percent of those on older drugs. ,The ... Norvasc and Coversyl with a beta-blocker and a diuretic. ...
... the American Medical Association finds that despite the existing ... training, or// residency includes shifts that involve working long ... Medical Education (ACGME) say that they must be allowed ... Medical School, and colleagues said that interns reported working ...
Cached Medicine News:Health News:Anticipation Could Have An Intense Effect On Memory 2Health News:Anticipation Could Have An Intense Effect On Memory 3Health News:Burka Style Inter-faith Gowns For Muslim Patients In UK 2
(Date:9/17/2014)... Women everywhere know how frustrating a vaginal ... they,re often also embarrassing and have a way of ... ( http://ph-defense.com ) is a new, over-the-counter product designed ... product. Odor, discharge, and discomfort or ... In many cases, the cause of such problems can ...
(Date:9/17/2014)... N.J. , Sept. 17, 2014   ... details how to implement GS1 Standards to support ... and enhance patient safety and security in the ... Applying GS1 Standards to U.S. Pharmaceutical Supply Chain ... Security Act , was developed in collaboration ...
(Date:9/17/2014)... MILL VALLEY, Calif. , Sept. 17, ... announced a partnership in the fight against sarcoma. ... Sarcoma Alliance Suzanne Renee Leider Memorial Assistance Fund. ... assistance to reimburse sarcoma patients for expenses directly ... sarcoma specialist. Scientific literature reinforces the importance of ...
Breaking Medicine Technology:New Product from Vireo Systems: pH-D Feminine Health Support 2New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 2New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 3New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 4Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 2Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 3
... Inc., the global leader in cold chain visibility ... (IATA) has deemed Sensitech,s full range of temperature ... with the 53rd edition of the IATA Dangerous ... the United Nations.   The size and lithium metal ...
...  Online news publication in-PharmaTechnologist.com ... news in key biopharma manufacturing niches. Using the ... of four microsites - Ingredients , Processing , ... - each of which delivers highly targeted news. ...
Cached Medicine Technology:Sensitech Inc. Products Receive Regulatory Compliance Approval from IATA 2Industry Leading Pharmaceutical News Website in-Pharmatechnologist.com Refocused and Relaunched 2
Two-channel, Berman design. Semirigid, nontoxic polyethylene. Individually packaged, 48 per case. Latex Free....
Black elastomer. Smooth finish. Non-Sterile....
Guedel-style enclosed center channel. Semirigid, nontoxic polyethylene with color-coded bite block. Individually packaged, 48 per case. Latex Free....
Includes one of each size airway. Plastic. Color coded for size. Single use. Non-Sterile....
Medicine Products: