Navigation Links
Saliva Test Spots Virus That Can Cause Hearing Loss in Newborns
Date:6/2/2011

THURSDAY, June 2 (HealthDay News) -- A new study finds that a saliva test in newborns can detect almost all cases of a virus that can cause birth defects and hearing loss.

The test could allow doctors to get a head start on preventing or treating deafness in children infected with the virus, known as cytomegalovirus.

The traditional "heel stick" blood test for newborns doesn't do a good job of detecting the infection, which is passed from mother to child and affects tens of thousands of babies each year, although most don't suffer any ill effects. The test misses 60 percent to 70 percent of cases.

Cytomegalovirus is "the epidemic that nobody's ever heard of," said Dr. Mark Schleiss, director of the University of Minnesota Medical School's division of pediatric infectious diseases and immunology. "This virus causes more birth defects in babies than any other infectious disease in the United States today."

In the new study, published in the June 2 issue of the New England Journal of Medicine, researchers at the University of Alabama at Birmingham and colleagues examined mouth swabs taken from almost 35,000 infants from seven U.S. hospitals. They were taken when babies were about a day old.

The researchers tested the samples and confirmed their results using a testing procedure that's too unwieldy for widespread screening use.

They found that the test correctly detected the virus in 97 percent to 100 percent of cases. Just 13 positive tests were incorrect, possibly because secretions from the mother made it into the mouths of the babies, the researchers said.

"We now know that we have a test with saliva that works," study co-author Dr. Suresh Boppana said in a news release from the National Institute on Deafness and Other Communication Disorders. "The challenge is, unlike the dried blood spot [heel stick], which is already used for newborn screening in hospitals across the country, we don't have a system in place for the collection of saliva. But we've shown that if you wanted to test a lot of babies for congenital CMV infection, it can be done."

Schleiss praised the study as "outstanding and meticulous." In regard to deafness, he said, the test could alert physicians to the potential for hearing loss in infected infants -- even if a newborn hearing test doesn't show any problems -- and allow doctors to give preventive drugs or provide hearing aids.

More information

For more on cytomegalovirus, try the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Mark Schleiss, director, division of pediatric infectious diseases and immunology, University of Minnesota Medical School; June 2, 2011, The New England Journal of Medicine


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
2. Cutting-edge salivary diagnostics research presented at AADR 3rd Fall Focused Symposium
3. Salivary glands as organs of immunity: New research makes oral immunization easier to swallow
4. Validation of salivary-biomarkers for Sjogrens syndrome detection in US population
5. Pre-Season Test Spots Baseball Pitchers at Risk of Injury
6. New Polycarbonate Sign Face Material Eliminates Hot Spots, Optimizes Light Uniformity in LED Back-Lit Signs
7. Science Reveals Secrets of Animals Spots, Stripes
8. Test Spots Potential Organ Donors Among Coma Patients
9. Finding cancer cold spots can help minimize radiotherapy side-effects
10. Leopard Spots, Tiger Stripes Aid Camouflage, Study Finds
11. Scientists Aim for Test That Spots Single Cancer Cell in Blood Sample
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Saliva Test Spots Virus That Can Cause Hearing Loss in Newborns
(Date:2/5/2016)... ... February 05, 2016 , ... The ... funding innovative lymphoma research and serving the lymphoma community through a comprehensive series ... again host, Swirl, A Wine Tasting Event at the La Gorce Country Club ...
(Date:2/5/2016)... ... February 05, 2016 , ... In ... across the country gathered at the La Valencia Hotel in San Diego, California ... Chicago was named the year’s most outstanding franchise, walking away with the coveted ...
(Date:2/5/2016)... ... February 05, 2016 , ... Regular gym users know the ... to wait longer to access the treadmills. It’s a predictable trend. After the excesses ... weight and get in shape by joining gyms, starting new walking or running routines, ...
(Date:2/5/2016)... ... February 05, 2016 , ... Boar’s Head Brand®, one of the nation’s leading ... Big Game. Take the stress out of your party preparation – follow these easy, ... every stage of the game. , “The key to hosting a successful game-day party ...
(Date:2/5/2016)... ... 2016 , ... At its annual meeting held last week, the American Parkinson ... Board of Directors. Mr. McDermott succeeds former APDA Chairman, Fred Greene. , "We are ... , APDA President and CEO. “Pat has tirelessly served APDA since 2001 when he ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016  Montoya Love is recognized by Continental Who,s ... Pharmaceuticals. Montoya is the Regulatory Systems Operations Manager with ... Manufacturing and selling a broad range ... provides healthcare institutions, clinical laboratories and life science researchers ... the globe. ...
(Date:2/4/2016)... Feb. 4, 2016 Frontier Pharma: Chronic ... First-in-Class Innovation Chronic Obstructive Pulmonary ... chronic inflammation of the airways and lungs. Persistent ... make the disease one of the leading causes ... in the world. COPD is linked to cumulative ...
(Date:2/4/2016)... 4, 2016  Aethlon Medical, Inc. (Nasdaq: ... devices to treat life-threatening diseases, today announced results ... December 31, 2015. --> ... forth in our last quarterly call, we strategically ... long-term objective to establish the Aethlon Hemopurifier® as ...
Breaking Medicine Technology: