Navigation Links
Saliva Test Could Indicate Autism
Date:1/16/2009

Presence of abnormal proteins might be sign of the condition, study says

FRIDAY, Jan. 16 (HealthDay News) -- A saliva test might one day help doctors detect some forms of autism, potentially leading to early treatments for children with the developmental disorder, Italian researchers say.

Scientists will need to confirm the results of the study released this month, which looked at just 27 people with autism. Follow-up research has failed to confirm the findings of similar small studies, one specialist said.

Still, "there is much hope for the future in autism research, and this study offers a possible new approach," said the specialist, Dr. Andrew Zimmerman, a pediatric neurologist and director of medical research at the Center for Autism and Related Disorders at the Kennedy Krieger Institute in Baltimore.

An estimated one in 150 people is diagnosed with autism, a condition that makes it difficult for people to communicate and understand the emotions of others.

The causes of autism remain unclear in about 90 percent of children who have symptoms, Zimmerman said. "There are no tests we can do to identify underlying biological signs consistently," he said. "In other words, we need clues to the biological processes that will shed light on the mechanisms that lead to autism, and provide clinical markers of the process."

Reliable tests "will be able to identify children at risk or affected early in the process so that intervention with various forms of therapy can be started early or used for prevention," Zimmerman said.

In the new study, published in the Jan. 2 issue of the Journal of Proteome Research, researchers said they have a saliva test that holds promise.

The researchers said the test showed that the saliva of 18 of 27 autistic patients revealed abnormal proteins. It's possible that the proteins could be a sign of problems in brain development during infancy, said the study's lead author, Massimo Castagnola, a researcher with Università Cattolica in Rome.

There are some caveats, however, Castagnola said. For starters, autistic patients typically aren't cooperative. And it's not clear what treatment would follow a positive diagnosis.

Future research is needed to determine the connection between test results and signs of autism, Castagnola said.

Zimmerman, who had no role in the study but is familiar with its findings, cautioned that autism comes in many forms, and a test of proteins in saliva "might not correlate specifically in certain types of patients with autism and might not be consistent over time."

Still, the new study offers "exciting possibilities" for understanding autism through the cells and chemical processes in the body, he said.

More information

To learn more about autism, visit Autism Speaks.



SOURCES: Andrew Zimmerman, M.D., pediatric neurologist and director, medical research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore; Massimo Castagnola, researcher, Università Cattolica, Rome; Jan. 2, 2009, Journal of Proteome Research


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bat Saliva-Based Stroke Drug Disappoints in Trial
2. Bi-Coastal Pharmaceutical Corp. Acquires U.S. Marketing Rights to Aquoral(TM) Artificial Saliva Product
3. Melvin receives Salivary Research Award
4. Salivary diagnostics, the magic mirror to your health ... at your personal computer
5. UT Health Science Center researchers decoding saliva to detect breast cancer
6. Economic Stimulus Package Could Impinge on Americans Health Privacy
7. Congressional Action Could Harm Physician Hospitals; Economic Impact Could Be Severe Warns PHA
8. Identification of genetic markers for ulcerative colitis could lead to treatment
9. Cost containment focus could have consequences for health care delivery
10. Researchers discover target that could ease spinal muscular atrophy symptoms
11. War Vets With Headaches Could Have Brain Problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... "With 30 ... their specific project," said Christina Austin - CEO of Pixel Film Studios. , ... and all within Final Cut Pro X . Simply select a ProHand generator ...
(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Consumers have taken a more ... placed more emphasis on patient outcomes. ... in the pharmaceutical industry have evolved beyond just ... companies are focusing on becoming more patient-oriented across ... and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, ... -based mobile pulmonary function testing company, is now able to perform ... developed by ndd Medical Technologies , Inc. ... in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL ... can get any needed testing done in the comfort of her ...
Breaking Medicine Technology: