Navigation Links
Saliva Test Could Indicate Autism
Date:1/16/2009

Presence of abnormal proteins might be sign of the condition, study says

FRIDAY, Jan. 16 (HealthDay News) -- A saliva test might one day help doctors detect some forms of autism, potentially leading to early treatments for children with the developmental disorder, Italian researchers say.

Scientists will need to confirm the results of the study released this month, which looked at just 27 people with autism. Follow-up research has failed to confirm the findings of similar small studies, one specialist said.

Still, "there is much hope for the future in autism research, and this study offers a possible new approach," said the specialist, Dr. Andrew Zimmerman, a pediatric neurologist and director of medical research at the Center for Autism and Related Disorders at the Kennedy Krieger Institute in Baltimore.

An estimated one in 150 people is diagnosed with autism, a condition that makes it difficult for people to communicate and understand the emotions of others.

The causes of autism remain unclear in about 90 percent of children who have symptoms, Zimmerman said. "There are no tests we can do to identify underlying biological signs consistently," he said. "In other words, we need clues to the biological processes that will shed light on the mechanisms that lead to autism, and provide clinical markers of the process."

Reliable tests "will be able to identify children at risk or affected early in the process so that intervention with various forms of therapy can be started early or used for prevention," Zimmerman said.

In the new study, published in the Jan. 2 issue of the Journal of Proteome Research, researchers said they have a saliva test that holds promise.

The researchers said the test showed that the saliva of 18 of 27 autistic patients revealed abnormal proteins. It's possible that the proteins could be a sign of problems in brain development during infancy, said the study's lead author, Massimo Castagnola, a researcher with Università Cattolica in Rome.

There are some caveats, however, Castagnola said. For starters, autistic patients typically aren't cooperative. And it's not clear what treatment would follow a positive diagnosis.

Future research is needed to determine the connection between test results and signs of autism, Castagnola said.

Zimmerman, who had no role in the study but is familiar with its findings, cautioned that autism comes in many forms, and a test of proteins in saliva "might not correlate specifically in certain types of patients with autism and might not be consistent over time."

Still, the new study offers "exciting possibilities" for understanding autism through the cells and chemical processes in the body, he said.

More information

To learn more about autism, visit Autism Speaks.



SOURCES: Andrew Zimmerman, M.D., pediatric neurologist and director, medical research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore; Massimo Castagnola, researcher, Università Cattolica, Rome; Jan. 2, 2009, Journal of Proteome Research


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Bat Saliva-Based Stroke Drug Disappoints in Trial
2. Bi-Coastal Pharmaceutical Corp. Acquires U.S. Marketing Rights to Aquoral(TM) Artificial Saliva Product
3. Melvin receives Salivary Research Award
4. Salivary diagnostics, the magic mirror to your health ... at your personal computer
5. UT Health Science Center researchers decoding saliva to detect breast cancer
6. Economic Stimulus Package Could Impinge on Americans Health Privacy
7. Congressional Action Could Harm Physician Hospitals; Economic Impact Could Be Severe Warns PHA
8. Identification of genetic markers for ulcerative colitis could lead to treatment
9. Cost containment focus could have consequences for health care delivery
10. Researchers discover target that could ease spinal muscular atrophy symptoms
11. War Vets With Headaches Could Have Brain Problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® ... Group (TGIG), has initiated cultivation and processing operations at its production facility, and ... Nevada. , Puradigm is the manufacturer of a complete system of proactive air ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
Breaking Medicine Technology: