Navigation Links
Saliva May Help Spot Oral Cancer Early
Date:8/25/2009

Study suggests potential for a non-invasive diagnostic test

TUESDAY, Aug. 25 (HealthDay News) -- In a major step towards early diagnosis of oral cancer, researchers have found that saliva contains at least 50 microRNAs that could aid detection.

In the study, U.S. researchers measured microRNA levels in the saliva of 50 people with oral squamous cell carcinoma and 50 healthy people. They identified at least 50 microRNAs that may be associated with oral cancer.

The levels of two of those -- miR-125a and miR-200a -- were significantly lower in the cancer patients than in healthy people, the researchers found.

MicroRNAs are molecules that control activity and assess the behavior of multiple genes, according to background information in a news release about the study from the American Association for Cancer Research.

"The oral cavity is a mirror to systemic health, and many diseases that develop in other parts of the body have an oral manifestation," study author Dr. David T. Wong, a professor at the University of California, Los Angeles School of Dentistry, said in the news release.

The study findings, published online Aug. 25 in the journal Clinical Cancer Research, need to be confirmed by a larger and longer analysis, Wong said.

"It is a Holy Grail of cancer detection to be able to measure the presence of a cancer without a biopsy, so it is very appealing to think that we could detect a cancer-specific marker in a patient's saliva," Dr. Jennifer Grandis, a professor of otolaryngology and pharmacology at the University of Pittsburgh School of Medicine and Cancer Institute, said in the news release. She is also a senior editor of Clinical Cancer Research.

More information

The U.S. National Cancer Institute has more about oral cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, Aug. 25, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. UT Health Science Center researchers decoding saliva to detect breast cancer
2. Salivary diagnostics, the magic mirror to your health ... at your personal computer
3. Melvin receives Salivary Research Award
4. Bi-Coastal Pharmaceutical Corp. Acquires U.S. Marketing Rights to Aquoral(TM) Artificial Saliva Product
5. Bat Saliva-Based Stroke Drug Disappoints in Trial
6. Saliva Test Could Indicate Autism
7. Saliva Test Could Monitor Type 2 Diabetes
8. Parents In Kansas Can Now Test Their Children For Lead Exposure Using Saliva
9. Parents in Missouri Can Now Test Their Children for Lead Exposure Using Saliva
10. Parents In Pennsylvania Can Now Test Their Children For Lead Exposure Using Saliva
11. Parents In Wisconsin Can Now Test Their Children For Lead Exposure Using Saliva
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Saliva May Help Spot Oral Cancer Early
(Date:10/13/2017)... ... October 13, 2017 , ... ... in the greater Dallas, Miami, and Raleigh regions, is organizing an extended charity ... a rare and deadly chromosome abnormality. , After struggling since birth with several ...
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association ... standards of excellence for the field of eating disorders, announces the opening of ... 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. , ...
(Date:10/13/2017)... ... , ... Many families have long-term insurance that covers care for a family ... for care if the client has a cognitive impairment diagnosis. , “What this ... often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, owner ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob ... sciatica in a new episode of "Success Files," which is an award-winning educational ... and investigates each subject in-depth with passion and integrity. , Sciatica occurs when ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium , ... File solutions, today—from the IQPC Trial Master Files ... , NL)—announced that EastHORN Clinical Services has selected ... programs and TMF management. EastHORN, a leading European ... platform to increase transparency to enable greater collaboration ...
(Date:9/19/2017)... 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, ... three leadership team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has ...
Breaking Medicine Technology: