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SYNTAX defines borders between CABG and PCI with TAXUS drug-eluting stents
Date:2/23/2009

Coronary artery bypass grafting (CABG) should remain the "standard of care" for patients with complex coronary artery disease, concludes the SYNTAX study, published in the New England Journal of Medicine (online February 18, 2009, Print edition March 5).

The SYNTAX study, led jointly by Patrick Serruys from Erasmus University Medical Center (Rotterdam, the Netherlands) and Fred Mohr from the University of Leipzig (Germany), set out to compare CABG and PCI using DES to investigate whether the situation has changed. The findings of the SYNTAX study were first presented at the European Society of Cardiology meeting in Munich, August 30 to September 3, 2008.

Improved technology is making it possible to treat increasingly complex coronary artery lesions with percutaneous coronary intervention (PCI), a technique first introduced in 1977. But studies comparing PCI using bare metal stents (BMS) with CABG - such as the ARTS I, SoS and MASS II studies - showed that higher rates of repeat revascularization procedures were needed following PCI. Set against this background, other studies have been showing that newer drug eluting stents (DES) require less repeat revascularization than the older BMS.

Commenting on the study, Dr William Wijns, spokesperson for the European Society of Cardiology and president of the European Association for Percutaneous Cardiovascular Interventions (EAPCI) said: "The SYNTAX study shows the importance of including both interventional cardiologists and cardiac surgeons in the decision making process. The fact SYNTAX concludes CABG should be considered the standard of care means all centres should be standing back and considering it."

But before drawing any firm conclusions from the SYNTAX data, he cautioned, it is important to wait for the two year update, expected to be presented at the European Society of Cardiology annual meeting in September 2009. "The big caveat with SYNTAX is that with CABG the hi
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Contact: ESC Press Office
press@escardio.org
33-049-294-8627
European Society of Cardiology
Source:Eurekalert

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