Navigation Links
SSRI Antidepressants May Lower Adult Suicide Risk
Date:2/3/2009

But their effect on depressed individuals under 25 remains unclear, researchers say

TUESDAY, Feb. 3 (HealthDay News) -- Selective serotonin reuptake inhibitors (SSRIs) may significantly reduce the risk of attempted or completed suicide in depressed adults, according to a review of eight large-scale observational studies.

SSRIs include such widely used antidepressants as Celexa, Paxil, Prozac and Zoloft.

The authors, from the World Health Organization and the University of Verona in Italy, conducted the review in order to assess whether SSRIs reduced or increased the risk of suicide in depressed people.

Some previous research, including a 2007 U.S. Food and Drug Administration study, concluded that the SSRI-related risk of suicide was neutral in adults, elevated in patients under 25, and reduced in people older than 65. In response to those findings, all antidepressants now include a black box warning regarding increased risk of suicidal symptoms in patients younger than 25.

"While the FDA found a neutral effect of SSRIs (or a promoting effect in adults aged 18-25), we found a strong protective effect associated with SSRI treatment in adults," wrote Dr. Corrado Barbui and colleagues.

The researchers concluded that "data from observational studies should reassure doctors that prescribing serotonin reuptake inhibitors in patients with major depression is safe," but children and adolescents taking the drugs should be closely monitored due to the possibility of suicidal thoughts and attempts.

The findings were published in the Canadian Medical Association Journal.

In a related commentary, two American experts called for randomized trials to determine the safety and efficacy of depression treatments for young adults. Such studies would help guide doctors, who have become extremely cautious when treating this group of patients.

Dr. John Mann of Columbia University and Dr. Robert Gibbons of the University of Illinois, said it's alarming that "concerns about the risk of suicide in youth have led not only to fewer SSRI prescriptions without substitution of alternative medications or psychotherapies, but also to a decrease in predicted rates of diagnosis of mood disorders."

More information

The U.S. National Institute of Mental Health has more about depression.



-- Robert Preidt



SOURCE: Canadian Medical Association Journal, news release, Feb. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Experimental Antidepressants Offer Faster Relief
2. Newer antidepressants led to less, not more, teen suicides
3. Antidepressants and painkillers - a dangerous combination
4. Antidepressants Boost GI Bleeding Risk
5. Study shows new strategy for developing antidepressants
6. Antidepressants Help HIV-Infected Patients Stick to Treatment
7. Genetics May Determine Antidepressants Effectiveness
8. Antidepressants that are more efficient and faster
9. Antidepressants Can Increase Depression, Impulsivity and Suicide Risk by Decreasing Dopamine
10. As depression symptoms improve with antidepressants, hopelessness can linger
11. Only Severely Depressed Benefit From Antidepressants: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
SSRI Antidepressants May Lower Adult Suicide Risk
(Date:4/25/2017)... , ... April 25, 2017 , ... Lake Park Dental ... by using Invisalign® in Lutz, FL. With the help of this highly-effective, ... aesthetics with fewer potential complications, more discretion and less pain. , Drs. Sarah ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... Buyers and ... recreational users to dispensaries and head shops –can’t help but be heartened by the ... the tell-tale cannabis odor aptly described as “skunk smell.” At last they can ...
(Date:4/25/2017)... ... April 25, 2017 , ... ... healthcare products, is introducing Flexadin UCII, part of the EQUISTRO line, at this ... joint health in horses at the immunologic level. , The scientifically-developed Flexadin UCII ...
(Date:4/24/2017)... ... April 24, 2017 , ... The Santana Telehealth Project was honored with the ... the American Telemedicine Association’s annual conference, on April 23 in Orlando, FL. , “I ... improve the lives of the poor and underserved in other parts of the world,” ...
(Date:4/24/2017)... ... ... Bright Pink , a national non-profit organization focusing on the prevention and early detection ... Pink is proud to announce Katie Thiede as their new Chief Executive Officer. In January, ... Chairman of the Board and launched a national search to find a visionary new leader ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 2017 Eyevensys, a private biotechnology ... gene expression technology that enables the safe, local, sustained ... a wide range of ophthalmic diseases, announces it has ... Regulatory Agency (MHRA) to advance its technology into clinical ... The ...
(Date:4/20/2017)... , April 20, 2017 Research and ... Pharmaceutical Contract Manufacturing Services Market Analysis By Service (Manufacturing, Research), ... Forecasts, 2014 - 2025" report to their offering. ... The Latin American pharmaceutical ... billion by 2025 Low drug registration cost in ...
(Date:4/19/2017)... Cardiology devices segment is anticipated to reach the highest market ... segment is likely to create absolute $ opportunity of a ... By the end of 2027, Cardiology Devices segment is projected ... expanding at a CAGR of 18.4% over the forecast period. ... reprocessed medical devices market in terms of revenue ...
Breaking Medicine Technology: