Navigation Links
SRI International's Research on Nicotine Use and Dependence Featured in the National Cancer Institute's Tobacco Control Monograph Series

MENLO PARK, Calif., Sept. 10 /PRNewswire/ -- SRI International, an independent nonprofit research and development institute, today announced that new research on nicotine dependence is featured in National Cancer Institute's Tobacco Control Monograph 20, Phenotypes and Endophenotypes: Foundations for Genetic Studies of Nicotine Use and Dependence. Gary E. Swan, Ph.D., director of SRI's Center for Health Sciences, was the senior scientific editor of the monograph.

"It was an honor to work with a broad range of experts to develop a greater understanding of behavioral genetics and how these findings can improve public health approaches to tobacco control," said Dr. Swan. "By understanding the role of genetics in the context of nicotine dependence, more effective treatment and prevention programs can be developed."

New studies by researchers from SRI's Center for Health Sciences are described in the monograph, including an analysis of subgroups among adolescent tobacco users. This research shows that the subgroup that started smoking at a younger age and maintained a high level of tobacco use is at high risk for adult nicotine dependence. The monograph also presents the first example of a metabolism ontology--a formal system to represent causal relationships between the administration of nicotine and its subsequent metabolism through the action of various genes. The monograph further summarizes work from the first-ever twin study of nicotine metabolism, work that was published previously and conducted by scientists working at SRI and elsewhere in the United States and Canada.

In the monograph, a review of current studies of tobacco use in twins and families is presented. The review concludes that nicotine dependence is a complex trait with genetic and environmental underpinnings that requires a cross-disciplinary approach to research to improve understanding of this behavior and its relationship to outcomes such as smoking cessation.

National Cancer Institute Tobacco Control Monograph 20 is available at:

About SRI's Center for Health Sciences

SRI's Center for Health Sciences uses a multidisciplinary research approach to address complex challenges that arise at the interface of the basic sciences, clinical medicine, health care economics, and the regulatory and legal environments. Its staff includes experts in medicine, psychology, sleep, genetic epidemiology, biostatistics, psychophysiology, biomedical legal issues, and public health.

About SRI International

Silicon Valley-based SRI International is one of the world's leading independent research and technology development organizations. SRI, which was founded by Stanford University as Stanford Research Institute in 1946 and became independent in 1970, has been meeting the strategic needs of clients and partners for more than 60 years. Perhaps best known for its invention of the computer mouse and interactive computing, SRI has also been responsible for major advances in networking and communications, robotics, drug discovery and development, advanced materials, atmospheric research, education research, economic development, national security, and more. The nonprofit institute performs sponsored research and development for government agencies, businesses, and foundations. SRI also licenses its technologies, forms strategic alliances, and creates spin-off companies. In 2008, SRI's consolidated revenues, including its wholly owned for-profit subsidiary, Sarnoff Corporation, were approximately $490 million.

SOURCE SRI International
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Research Seeks Cause of Preeclampsia
2. Sleep helps reduce errors in memory, MSU research suggests
3. UCSB researchers develop drug delivery system using nanoparticles and lasers
4. University of Arizona researchers seek safer cystic fibrosis test
5. Research Demonstrates that HerbalSciences Proprietary Elderberry Extract Prevents in Vitro H1N1 Influenza Infection
6. $0.00 Penny System to Jump Start Global Economy Developed by DNA and MIND Researcher.
7. Clarus Research Group Survey: Top Political Strategists React to Obamas Health Care Speech, Rate Effectiveness
8. New AOTMP Research Reveals that 21% of Enterprises Don't Have or Don't Know if they Have Telecom Expense Management Reporting
9. $3.5 million NIH grant supports AIDS vaccine research at UC Santa Cruz
10. DSS Research Announces Outbound Education and Verification Program Meets New CMS Requirements
11. Research Firm will Obtain Americans Reactions to the Presidents Speech on Health Care Reform
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... Insightra Medical, Inc. and Novus ... technology for soft tissue repair in the US via Insightra’s national direct sales ... mesh intended to support and reinforce soft tissue for 6-9 months before absorbing ...
(Date:11/30/2015)... ... 30, 2015 , ... SIMmersion’s ability to present dynamic scenarios ... of the future. To reach an audience of key visionaries and reformers in ... Chicago, organized by the American Medical Association. , AMA President Steven Stack, ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... enterprise Time and Attendance/Workforce Management cloud-based solutions, announced today that it has ... competencies in the Application Development, demonstrating a “best-in-class” ability and commitment to ...
(Date:11/30/2015)... November 30, 2015 (PRWEB) , ... ... ... and Winscribe are pleased to announce their strategic partnership at the Radiological ... consultants, SpeechCheck, Inc., and Winscribe, global providers of cutting-edge dictation and speech-enabled ...
(Date:11/30/2015)... ... 30, 2015 , ... World Patent Marketing , a ... household invention that provides an economical and easy way of gaining customized curtains. ... at 2.6%," says Scott Cooper, CEO and Creative Director of World Patent Marketing. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... --> adds "Global ... and "Investigation Report on China Repaglinide ... 2021 forecasts data and information to ... . --> ...
(Date:11/26/2015)... , Nov. 26, 2015 Research and ... of the "2016 Future Horizons and Growth ... Market: Supplier Shares, Country Segment Forecasts, Competitive Intelligence, ... --> --> ... of the Italian therapeutic drug monitoring market, including ...
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Cell Surface Marker Testing Market: Supplier ... to their offering.  --> ... of the  "2016 Future Horizons and ...
Breaking Medicine Technology: