Navigation Links
SIUE School of Pharmacy, SLU Pharmacology Receive $975K NIH Grant
Date:11/2/2009

;When you have inflammation in the body," Neumann explained, "reactive oxygen species and free radicals are produced, which can lead to formation of the neurotoxic molecule, peroxynitrite. Normally, these reactive molecules are kept under tight wraps by the body's own antioxidant defense systems.

"But, if these systems become compromised, as in a state of chronic pain, it actually can make the problem worse. We'll be looking at creating a synthetic enzyme that will go in and destroy the peroxynitrite."

Over the past decade, Salvemini's pioneering research led to the discovery of peroxynitrite. "We discovered the substance ... which turns out to be very important in the development of pain and inflammation. If we target that molecule, we hope we can find new therapies with fewer side effects," said Salvemini.

"Currently, pain is often poorly managed. Our hope is to find better ways to eliminate human suffering."

The two-year grant is being administered through the NIH's National Institute of Arthritis and Musculoskeletal And Skin Diseases. "By using various accepted lab methods, we will try to create in rats arthritic conditions and see how they react to the pharmacology we introduce," Neumann said. "The broad potential therapeutic use of these new analgesic agents we're proposing is not a part of current pain management drugs," he said.

"Our team will draw upon previous breakthroughs in the development of free radical targeted therapies but we will go further in creating a new approach to combat the problem without some of the current side effects of current pain management drugs."

William Neumann received a bachelor of science in Chemistry from the University of Missouri at Columbia in 1983 and a doctorate in 1987 from UM-St. Louis, where he worked on synthetic methodologies directed at preparing antitumor cyclopentanoid natural products. Sin
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Time to Set Kids Back-to-School Sleep Clocks
2. Add Earlier Bedtime to Back-to-School List
3. Does Pathological Shyness Make for School Shooters?
4. Mailman School of Public Health study examines link between racial discrimination and substance use
5. Survey reveals disparities in skin cancer knowledge, protection among high school students
6. Non-medicinal treatment touted for pre-schoolers with ADHD
7. Nonmedicinal treatment touted for preschoolers with ADHD
8. Obese Children Miss More School Days
9. Back to School Means Backpack Safety
10. Heart Attacks at School Involve More Adults Than Kids
11. Back to School Means Return of School Blood Drives
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
SIUE School of Pharmacy, SLU Pharmacology Receive $975K NIH Grant 
(Date:5/29/2015)... May 29, 2015 Johnson & ... a confidential Risperdal lawsuit ( http://www.risperdallawsuit2014.com/ ) settlement ... due to his use of the antipsychotic medication. ... selected for the third bellwether trial to involve ... litigation underway in Pennsylvania’s Philadelphia Court of Common ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 The ... the graduates of its Advanced Training Program (ATP) ... who fill roles in their health care organization ... theory and methodology of continuous quality improvement in ... sister-program to Dr. Brent James’ internationally recognized Advanced ...
(Date:5/29/2015)... A group of doctors have discovered “The Cure ... to teach this “new math” to children in early childhood ... by the recent implementation of Common Core Math in classrooms ... Core is now a reality in children’s classrooms in 44 ... seeking ways to improve common core math training for their ...
(Date:5/29/2015)... 2015 World Patent Marketing, a vertically ... it has signed a 10 year licensing agreement for ... to let people learn about any topic and get ... "This is an exciting day for World Patent Marketing ... Cooper, CEO and Creative Director of World Patent Marketing, ...
(Date:5/29/2015)... FL (PRWEB) May 29, 2015 ... Utah, recently partnered with Stratus Video ... which will facilitate better communication and timely ... (LEP) and hearing loss. Stratus’ video remote ... in-house translators, enabling staff to quickly access ...
Breaking Medicine News(10 mins):Health News:Risperdal Lawsuit Selected as Pennsylvania’s Third Bellwether Gynecomastia Case Settles Hours Before Trial 2Health News:Risperdal Lawsuit Selected as Pennsylvania’s Third Bellwether Gynecomastia Case Settles Hours Before Trial 3Health News:HORNE LLP’s Healthcare Delivery Institute Graduates Class from the Advanced Training Program 2Health News:Doctors Discover a Cure for the Common Core 2Health News:Licensing Alert! World Patent Marketing's Latest Blockbuster Licensing Deal Gets A New Twist on Technology With The Live Expert Chat Room 2Health News:Licensing Alert! World Patent Marketing's Latest Blockbuster Licensing Deal Gets A New Twist on Technology With The Live Expert Chat Room 3Health News:Licensing Alert! World Patent Marketing's Latest Blockbuster Licensing Deal Gets A New Twist on Technology With The Live Expert Chat Room 4Health News:Licensing Alert! World Patent Marketing's Latest Blockbuster Licensing Deal Gets A New Twist on Technology With The Live Expert Chat Room 5Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 2Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 3Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 4
... , ... ... ... , ...
... ... ... ... ...
... MS Awareness Week March 8-14 is the ... someone is newly diagnosed every hour of every day. Supported by a Congressional resolution, this year ... world free of MS! , ... March 8, 2010 -- MS Awareness Week March 8-14 is the time for the nation ...
... , ... ... ... ...
... ... pictures that are better than anything that’s come before. With the new technology they’ve developed, ... in the heart and the major arteries around it. , ... Madison, WI (PRWEB) March 8, 2010 -- What does the ...
... ... announced today they have been named as the preferred distributor of Gendron bariatric care ... Gendron bariatric care medical equipment to healthcare professionals who wish to purchase or lease. ... Issaquah, WA. ...
Cached Medicine News:Health News:World Cocoa Foundation Launches Cocoa Livelihoods Program in Nigeria 2Health News:World Cocoa Foundation Launches Cocoa Livelihoods Program in Nigeria 3Health News:World Cocoa Foundation Launches Cocoa Livelihoods Program in Nigeria 4Health News:World Cocoa Foundation Launches Cocoa Livelihoods Program in Nigeria 5Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 2Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 3Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 4Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 5Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 6Health News:Beverage Industry Delivers On Commitment to Remove Regular Soft Drinks In Schools, Driving 88% Decline In Calories 7Health News:MOVE IT! Join the Movement to End Multiple Sclerosis During MS Awareness Week March 8-14, 2010, 2Health News:MOVE IT! Join the Movement to End Multiple Sclerosis During MS Awareness Week March 8-14, 2010, 3Health News:MOVE IT! Join the Movement to End Multiple Sclerosis During MS Awareness Week March 8-14, 2010, 4Health News:MOVE IT! Join the Movement to End Multiple Sclerosis During MS Awareness Week March 8-14, 2010, 5Health News:MOVE IT! Join the Movement to End Multiple Sclerosis During MS Awareness Week March 8-14, 2010, 6Health News:I'm Not Crazy...I'm Just Not You 2Health News:I'm Not Crazy...I'm Just Not You 3Health News:I'm Not Crazy...I'm Just Not You 4Health News:I'm Not Crazy...I'm Just Not You 5Health News:I'm Not Crazy...I'm Just Not You 6Health News:Heart Aflutter? Remarkable New Images Show What it Looks Like in 4-D 2Health News:Heart Aflutter? Remarkable New Images Show What it Looks Like in 4-D 3Health News:QuickMedical Launches New Line of Medical Equipment for Bariatric Care 2Health News:QuickMedical Launches New Line of Medical Equipment for Bariatric Care 3
(Date:5/29/2015)... , May 29, 2015  Anpac Bio-Medical Science ... Chris Yu and the Anpac research team are ... Biomedical Science (NPLS) organizers published as, "game changing" and ... American Society of Clinical Oncology (ASCO) Annual Meeting in ... June 2, 2015. An accomplished inventor ...
(Date:5/29/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/64lx2w/north_america_mri ) ... MRI Market - Growth, Trends And Forecasts (2014 - ... North American MRI systems market is estimated to increase ... billion by 2020 with a CAGR of 2.9% between ... namely, the open system, closed system and the standing ...
(Date:5/29/2015)... , May 29, 2015  Fair Rate Funding, ... a state-court jury in Delaware ... inserts, designed to treat pelvic organ prolapse (POP) and ... and that company executives hid the design flaws from ... - http://photos.prnewswire.com/prnh/20150529/219354LOGO Transvaginal mesh, ...
Breaking Medicine Technology:Anpac Bio-Medical Introduces 'Game Changing' Cancer Screening Tech at American Society of Clinical Oncology Meeting - Chicago 5/29 - 6/2 2Anpac Bio-Medical Introduces 'Game Changing' Cancer Screening Tech at American Society of Clinical Oncology Meeting - Chicago 5/29 - 6/2 3North America MRI Market - Growth, Trends And Forecasts 2014-2019 with GE, Hitachi Medical, Philips Healthcare, Siemens Healthcare & Toshiba Medical Systems Dominating 2TV Mesh Lawsuit Funding Firm, Fair Rate Funding, Reports Delaware Woman Awarded $100 Million Against Boston Scientific in Pelvic Mesh Verdict. 2TV Mesh Lawsuit Funding Firm, Fair Rate Funding, Reports Delaware Woman Awarded $100 Million Against Boston Scientific in Pelvic Mesh Verdict. 3
... SAN DIEGO, May 5, 2011 Ridge Diagnostics, Inc., ... will speak at the 6th Annual Neurotech Investing and Partnering ... St. Regis Hotel on May 9th and 10th.   ... on a panel entitled "Next Generation Psychiatry" lead by Dr. ...
... N.J., May 4, 2011 Savient Pharmaceuticals, Inc. (NASDAQ: ... through its wholly owned subsidiary, Savient Pharma Ireland Limited, ... and the assigned co-rapporteurs, the Marketing Authorization Application (MAA) ... in adult patients refractory to conventional therapy. Currently there ...
Cached Medicine Technology:Ridge Diagnostics, Inc. CEO to Speak at Neurotech Investing and Partnering Conference 2Savient Pharmaceuticals Submits European Marketing Authorization Application for KRYSTEXXA® 2Savient Pharmaceuticals Submits European Marketing Authorization Application for KRYSTEXXA® 3Savient Pharmaceuticals Submits European Marketing Authorization Application for KRYSTEXXA® 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: