Navigation Links
SGX Pharmaceuticals Submits Investigational New Drug Application for SGX523, a Highly Potent, Selective, Orally Bioavailable cMET Inhibitor
Date:12/3/2007

SAN DIEGO, Dec. 3 /PRNewswire-FirstCall/ -- SGX Pharmaceuticals, Inc. (Nasdaq: SGXP) today announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for SGX523. This compound is an internally developed, orally-bioavailable, small molecule inhibitor of the cMET receptor tyrosine kinase. The Company expects to begin Phase I clinical trials of SGX523 for solid tumor cancer patients in early 2008.

"This IND submission is one quarter earlier than originally anticipated and represents a significant achievement for our organization," said Mike Grey, President and Chief Executive Officer of SGX Pharmaceuticals. "Submission of the SGX523 IND package less than ten months after the compound's nomination as a formal development candidate speaks highly of the effectiveness of our research and development capabilities. We look forward to capitalizing on this positive momentum and initiating clinical studies in solid tumor cancer patients following FDA review of our submission."

About SGX523 and cMET

SGX523 has shown significant selectivity for the cMET receptor tyrosine kinase over more than 200 protein kinases and has demonstrated both potent in vitro blockade of the activity of this cancer target and in vivo activity against human cancer cells that depend on cMET for their uncontrolled growth and proliferation. The cMET receptor tyrosine kinase has been implicated in a wide range of cancers, including both solid and blood tumors. cMET has been extensively studied in both the laboratory environment and the clinic, with increasing data suggesting that uncontrolled stimulation of cMET plays a key role in a variety of effects associated with cancer, inc
'/>"/>

SOURCE SGX Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference
2. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
3. Transcept Pharmaceuticals, Inc. to Present at 2007 BIO Investor Forum
4. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
5. Idenix Pharmaceuticals to Present at Two Upcoming Investor Conferences
6. Vista Partners Updates Coverage on Tapestry Pharmaceuticals
7. Transcept Pharmaceuticals, Inc. to Present at UBS 2007 Global Life Sciences Conference
8. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc.
9. Amylin Pharmaceuticals to Webcast Corporate Overview During 43rd Annual Meeting of the European Association for the Study of Diabetes
10. Major Pharma Clinical Case Studies From Amgen, AstraZeneca, GSK, Intermune, Cephalon Inc, Sunesis Pharmaceuticals and Dartmouth Medical School During Fall Clinical Focused Programs
11. Provectus Pharmaceuticals, Inc. releases summary results of phase 1 metastatic melanoma study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... 13, 2014 Celebrity fitness trainer and ... a promotional partnership with Aqua Health Labs for their ... EPA supplement . The collaboration was recently announced live ... fitness trainer , actor, model, and a two time ... A-List celebrities, he has prepared stars including Demi Moore, ...
(Date:7/13/2014)... 13, 2014 If Dr. Lawrence Power has ... just launched at http://www.HealthYourself101.com will expand people’s understanding ... , Power has set out to provide a health education ... actually – dare we say it? – entertaining to dig ... “aims to engage the remote learner – the solitary individual ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Recently, iFitDress.com, ... and women’s special occasion outfits, has added a new ... website. Furthermore, the company has launched a promotion for ... discount. , iFitDress.com is now providing thousands of ... products sell well in Britain, America, France, Italy and ...
(Date:7/12/2014)... iFitDress.com, one of the world’s leading wedding dress suppliers, has ... What’s more, all these hot outfits are available at discounted ... states, “We are proud to announce our new red evening ... experience. In addition to the big discounts, low shipping costs ... always mean bad quality. All the red evening gowns are ...
(Date:7/12/2014)... 12, 2014 Fresh off their respective performances ... will meet on September 5th at Sun Life Stadium in ... see some of the brightest stars in the world of ... Miami will be treated to some of the best talent ... ranked as the third best team in the world according ...
Breaking Medicine News(10 mins):Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 3Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 4Health News:New and Beautiful Evening Dresses Unveiled by iFitDress.com 2Health News:Discounted Red Evening Gown Announced by iFitDress.com 2Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 2Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 3
... Invaluable Resource for Millions Who Want the Tax ... 2008, MILWAUKEE, Dec. 4 Consumers looking for ... advantage of health plans with,health savings accounts (HSAs) that ... site, http://www.HSAInsights.com, provides consumers and,employers with information ...
... 4 Selective Insurance,Group, Inc. announced the following ... ("Selective"):, Michael H. Lanza (Sparta, NJ), to ... Selective in 2004 as senior vice president and,general ... also,served as executive vice president and corporate secretary ...
... Industry and Technology Partners to Maximize Customer Value in Sales ... ... BLOOMFIELD HILLS, Mich., Dec. 4 gloStream, Inc.,(gloStream), an electronic ... formation of its,nationwide, multifaceted gloStream Certified Partner Network. The company,will deliver ...
... and alternative medicines (CAM) training for students in ... balanced, evidence-based advice to patients. , Dr ... of Pharmacy, has found CAM education integrated into ... attitudes. , A survey and interviews of ...
... athletes - often perceived as the epitome of health and ... are therefore proving useful in helping scientists understand more about ... at Griffith University, has enlisted elite rowers to help him ... barrier to infectious agents such as respiratory viruses. , ...
... release is also availabe in German . ... scientists at the Max Planck Institute for Evolutionary Anthropology ... 100,000 year old Belgian Neanderthal (Homo neanderthalensis). The report, ... USA (online edition early December), details how the team ...
Cached Medicine News:Health News:Video: New Web Site Helps Consumers and Employers Make Smart Choices on Health Savings Accounts (HSAs) 2Health News:Selective Insurance Group Announces Officer Appointments 2Health News:gloStream, Inc., Announces Formation of Nationwide Certified Partner Network 2Health News:gloStream, Inc., Announces Formation of Nationwide Certified Partner Network 3Health News:Complementary medicines training provides balance, not bias 2Health News:Exercising our immune system 2Health News:Neanderthal bearing teeth 2
(Date:7/10/2014)... 2014   Ventana Medical Systems, Inc.  (Ventana), a ... entered into an agreement with Merck KGaA, Darmstadt, ... in the United States and ... KGaA,s biopharmaceutical division on the development and commercialization of ... Ventana,s proprietary diagnostic assays. In alignment with Merck KGaA,s ...
(Date:7/10/2014)... 2014   LabStyle Innovations Corp . (OTCQB:DRIO), developer ... the appointment of Professor Richard B. Stone ... of Directors. Prof. Stone brings over ... LabStyle as an entrepreneur, venture capitalist public, company ... expert. He currently serves on the board of ...
(Date:7/10/2014)... Decision Resources Group finds that over half ... and Drug Administration,s (FDA) approval of Vifor Fresenius Medical ... approved by the FDA in November 2013 for the ... on dialysis. Other key findings from the ... : , Bundling: ...
Breaking Medicine Technology:Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3
... , July 30 PharmAthene, Inc. (NYSE Amex: ... against biological and chemical threats, today announced that on July ... LLC, stating that PharmAthene is not in compliance with the continued ... NYSE Amex Company Guide, because it has stockholders, equity of less ...
... 30 Conatus Pharmaceuticals Inc. announced today that Conatus ... disclosed.  Conatus Pharmaceuticals is a privately-held drug development company focused on liver ... , ... Ph.D., the former CEO of Idun Pharmaceuticals, which was acquired by Pfizer ...
Cached Medicine Technology:PharmAthene Provides Update on NYSE Amex Listing Compliance Plan 2PharmAthene Provides Update on NYSE Amex Listing Compliance Plan 3Conatus Pharmaceuticals Acquires Pfizer's Idun Subsidiary 2
2 tests on one meter. Glucose test for immediate glucose levels. GlucoProtein (Fructosamine) for overall control, average over prior 2-3 weeks. The Duet is the only hand held instrument to perform th...
The DOT-approved A150 test is used for workplace testing, most publicly for federally mandated testing of transportation workers, but also in private company "drug free workplace" programs. Each hash...
... QuickScreen multi-panel dip cards offer minimal exposure ... of any conceivable combination of 9 different ... your drug testing program. Just dip the ... timer tells you when to read the ...
... SureStep™ Drug Screen Tests are available in ... MDMA (Ecstasy). Designed using Microgenics Antibody Technology, ... only point of care immunoassay targeted to ... both MDA and MDEA but no cross-reactivity ...
Medicine Products: