Navigation Links
Rwandan genocide survivors provide new insights into resilience and PTSD
Date:2/25/2010

Philadelphia, PA, 25 February 2010 - The 1994 genocide in Rwanda resulted in the mass killing of up to one million people over the course of about 100 days. Although the exact death toll is unknown, experts estimate that as much as 20% of the country's entire population was murdered. There can be no doubt or surprise then that some of the survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder that can develop after witnessing or experiencing a traumatizing event, such as abuse, war, or natural disaster.

However, even under stress as extreme as genocide, not all individuals develop PTSD. Why is it that some do and some don't? A new study published in Biological Psychiatry, by Elsevier was designed to address that question.

The clues may come from molecular genetics. Scientists already know that, in general, the more traumatic events a person experiences, called 'traumatic load', the higher their likelihood of developing PTSD. In this new study, Iris-Tatjana Kolassa and her colleagues show that genetic factors influence this relationship.

They studied 424 Rwandan Genocide survivors, some with and some without PTSD. As expected, they found that those survivors with higher traumatic load had a higher prevalence of lifetime PTSD, a dose-response relationship. But importantly, they also found that the Val158Met polymorphism of the gene encoding the enzyme catechol-O-methyltransferase (COMT) plays a role in this relationship.

Individuals homozygous for the Met allele of this COMT polymorphism have substantially lower activity of this enzyme. Lower COMT activity would be expected to produce higher levels of norepinephrine and dopamine, neurotransmitters that are released during stress. Rwandan survivors with at least one Val allele in this gene showed the typical dose-response relationship between trauma severity and PTSD risk, but those homozygous for the Met allele exhibited a high risk for PT
'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Depression common among Rwandan youth who head households
2. Experiences of rape unique to Rwandan women survivors of genocide
3. mtvU Unleashes Month OF Exclusive Album Leaks & Music Video Premieres in Continued Fight Against Darfur Genocide
4. Agahozo-Shalom Youth Village in Rwanda Dedicated 15 Years After Genocide to Provide Healing Community to African Orphans
5. Rwanda Genocide 100-Day Commemoration Culminates With Kigali Festival With Andrew Palau
6. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
7. New York City Cancer Patients, Survivors and Care Givers Encouraged to Keep Going(R)
8. Chemotherapy may be culprit for fatigue in breast cancer survivors
9. Long-Term Fatigue Plagues Cancer Survivors
10. ASTRO, Wellness Community South Bay Cities Join to Promote Cancer Survivorship
11. Breast cancer survivors optimistic, yet lack critical information on reducing recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... US Preventive Services Task Force recommendations for screening and ... may be ameliorated through technological approaches according to a ... published online August 21, 2014 in the Journal ... David Levine, MD, MA, a third year resident in ... colleagues found that compared to usual care, technology-assisted interventions ...
(Date:8/29/2014)... 29, 2014 According to the ... accepting applications next month for medical marijuana, regulators, ... accepting marijuana as a legalized medicine. New marijuana ... be permitted to operate in accordance with local ... best suited to handle legal cannabis. , ...
(Date:8/29/2014)... The microbiology testing sector is one of the ... is also the hugest challenge facing suppliers during these ... of AIDS – still the world’s key health threat ... opportunistic infections (OIs); bioterrorism threat; advancements in technologies for ... Although for certain infections the etiology remains a mystery, ...
(Date:8/29/2014)... 2014 Floors of hospitals and other ... socks. Also, many patients are relegated to lying down ... recovery, Alzheimer’s, etc. Two inventors from Perrysburg, Ohio, have ... safety. , This special pair of socks helps prevent ... patients who are relegated to beds or chairs from ...
(Date:8/29/2014)... 2014 The 8th Annual Paint Columbus Pink® ... a Cause, Pink Pooch Contest, Light of Life Ceremony, Power ... Pink Bow Campaign – all in support of cancer awareness. ... this year…. Paint Columbus Pink Foam and Obstacle Challenge on ... 727 54th Street, Columbus, Georgia 31904. It will be the ...
Breaking Medicine News(10 mins):Health News:Options for weight loss your primary care doctor might not know about 2Health News:Medical Marijuana Approaches Legalization in Chicago 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 3Health News:Paint Columbus Pink Cancer Awareness/Kick-Off Meeting for Anyone Interested in Participating 2
... too much strain on or weaken children,s immune systems ... from the Robert Koch Institute investigate exactly this research ... International (Dtsch Arztebl Int 2011; 108(7): 105-11). Their ... Health Interview and Examination Survey for Children and Adolescents ...
... the early data from Understanding Society based on 14,000 UK ... people with higher levels of education and by married people. ... on sleep, with those in routine occupations reporting worse sleep ... at the University of Surrey who analysed the findings said: ...
... , THURSDAY, March 3 (HealthDay News) -- More than ... a night, which affects their concentration and general health, ... work performance and the ability to drive safely, found ... Prevention (CDC), which published two sleep studies March 4 ...
... combined effects of chemotherapy and endocrine therapy may increase ... In a study scheduled for publication in the April ... Rehabilitation , researchers from the Oregon Health & Science ... survivors whether they had fallen in the past year ...
... , THURSDAY, March 3 (HealthDay News) -- An analysis ... women with breast cancer, a new study reports. Researchers ... breast cancer tumors, and found that the way collagen fibers ... may aid in a patient,s diagnosis and help determine treatment. ...
... , THURSDAY, March 3 (HealthDay News) -- New ... improved sleep treatments, a new study suggests. A team ... as the emblem of wakefulness persists in a hidden form ... -- something that appears to affect people,s vulnerability to being ...
Cached Medicine News:Health News:The better off sleep better 2Health News:1 in 3 Americans Gets Less Than 7 Hours of Sleep: CDC 2Health News:1 in 3 Americans Gets Less Than 7 Hours of Sleep: CDC 3Health News:Breast cancer survivors at higher risk for falls 2Health News:Tissue Analysis May Help Predict Breast Cancer Outcome 2Health News:Particular Brain Rhythm in Sleep Makes You More Vulnerable to Disturbances 2
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "China Orthopedic Instrument Industry Report, 2014-2017" ... accelerated aging population and rising proportion of reimbursement for ... been effectively released, with its scale presenting a CAGR ... joint products are three product segments of orthopedic instruments ...
(Date:8/29/2014)... Research and Markets  has announced the addition of the ... their offering. The Central Nervous System (CNS) ... of pharmaceuticals industry. The numbers of CNS disorders have increased ... to meet the market requirements. There has been steady to ... the past two decades. The market for CNS therapies is ...
(Date:8/29/2014)... DENVER , Aug. 29, 2014 Does your ... date, nearly 800 doctors have recommended marijuana to the over ... Amendment 20. But the majority of the other roughly 20,300+ ... still know very little about it – even though a ... adults say they have tried it. ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2US CNS Disorders Drug Pipeline Insight 2014 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 3Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 4
... 2012 OPKO Health, Inc. and ChromaDex Corporation (OTCBB: ... alliance pursuant to which ChromaDex has licensed to OPKO ... technologies for distribution and business development throughout all of ... BluScience™ ( www.bluscience.com ), ChromaDex,s recently launched ...
... 2012 Uroplasty, Inc. (NASDAQ: UPI ), ... innovative proprietary products to treat voiding dysfunctions, today announced ... study in the United Kingdom. This large ... up to 20 centers across the UK. Using Uroplasty,s ...
Cached Medicine Technology:OPKO Health, Inc. Invests in ChromaDex® Corp. 2OPKO Health, Inc. Invests in ChromaDex® Corp. 3OPKO Health, Inc. Invests in ChromaDex® Corp. 4OPKO Health, Inc. Invests in ChromaDex® Corp. 5Uroplasty Announces Enrollment of First Patients in the CONFIDeNT Clinical Study for Treatment of Fecal Incontinence with Urgent® PC 2Uroplasty Announces Enrollment of First Patients in the CONFIDeNT Clinical Study for Treatment of Fecal Incontinence with Urgent® PC 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: