Navigation Links
Rwandan genocide survivors provide new insights into resilience and PTSD
Date:2/25/2010

Philadelphia, PA, 25 February 2010 - The 1994 genocide in Rwanda resulted in the mass killing of up to one million people over the course of about 100 days. Although the exact death toll is unknown, experts estimate that as much as 20% of the country's entire population was murdered. There can be no doubt or surprise then that some of the survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder that can develop after witnessing or experiencing a traumatizing event, such as abuse, war, or natural disaster.

However, even under stress as extreme as genocide, not all individuals develop PTSD. Why is it that some do and some don't? A new study published in Biological Psychiatry, by Elsevier was designed to address that question.

The clues may come from molecular genetics. Scientists already know that, in general, the more traumatic events a person experiences, called 'traumatic load', the higher their likelihood of developing PTSD. In this new study, Iris-Tatjana Kolassa and her colleagues show that genetic factors influence this relationship.

They studied 424 Rwandan Genocide survivors, some with and some without PTSD. As expected, they found that those survivors with higher traumatic load had a higher prevalence of lifetime PTSD, a dose-response relationship. But importantly, they also found that the Val158Met polymorphism of the gene encoding the enzyme catechol-O-methyltransferase (COMT) plays a role in this relationship.

Individuals homozygous for the Met allele of this COMT polymorphism have substantially lower activity of this enzyme. Lower COMT activity would be expected to produce higher levels of norepinephrine and dopamine, neurotransmitters that are released during stress. Rwandan survivors with at least one Val allele in this gene showed the typical dose-response relationship between trauma severity and PTSD risk, but those homozygous for the Met allele exhibited a high risk for PT
'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Depression common among Rwandan youth who head households
2. Experiences of rape unique to Rwandan women survivors of genocide
3. mtvU Unleashes Month OF Exclusive Album Leaks & Music Video Premieres in Continued Fight Against Darfur Genocide
4. Agahozo-Shalom Youth Village in Rwanda Dedicated 15 Years After Genocide to Provide Healing Community to African Orphans
5. Rwanda Genocide 100-Day Commemoration Culminates With Kigali Festival With Andrew Palau
6. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
7. New York City Cancer Patients, Survivors and Care Givers Encouraged to Keep Going(R)
8. Chemotherapy may be culprit for fatigue in breast cancer survivors
9. Long-Term Fatigue Plagues Cancer Survivors
10. ASTRO, Wellness Community South Bay Cities Join to Promote Cancer Survivorship
11. Breast cancer survivors optimistic, yet lack critical information on reducing recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2015)... IL (PRWEB) February 26, 2015 Thousands ... small step to fund powerful progress for the Muscular ... by raising critical funds and awareness that will help ... fighting muscle disease. , “MDA Muscle Walk events unite ... for people whose abilities to move are compromised — ...
(Date:2/26/2015)... SpendWell Health, an online marketplace for ... first customer today, opening its doors to Cambia ... , SpendWell delivers the next generation of online ... transparency with e-commerce. SpendWell’s unique platform shows actual ... services and allows shoppers to buy those services ...
(Date:2/26/2015)... a nested-case control study of individuals living in the UK, ... of liver cancer, statin use is associated with a decreased ... published February 26 in the JNCI: Journal of the ... association but most used data from individuals living in regions ... Katherine A. McGlynn, Ph.D., from the Division of Cancer Epidemiology ...
(Date:2/26/2015)... NJ (PRWEB) February 26, 2015 The ... reopening of their newly renovated office in Lawrenceville, NJ. ... Reproductive Science Center of New Jersey’s physicians, and NJ ... and patient care in the areas of infertility and ... for having excellent success rates and providing current, high ...
(Date:2/26/2015)... The hip resurfacing procedure at ... Texas resident John Short to resume his active lifestyle, it ... to climb Mt. Kilimanjaro, the highest free-standing mountain in the ... Starting in his late 20s, Short suffered from early onset ... and sockets were bone on bone. , Then about ...
Breaking Medicine News(10 mins):Health News:MDA Kicks-Off Annual Muscle Walk Season in Local Communities Nationwide to Fight Back Against Muscle Disease 2Health News:MDA Kicks-Off Annual Muscle Walk Season in Local Communities Nationwide to Fight Back Against Muscle Disease 3Health News:SpendWell Launches New Online Health Care Marketplace to Large Employer Group 2Health News:SpendWell Launches New Online Health Care Marketplace to Large Employer Group 3Health News:RSCNJ Is Celebrating the Reopening of Their Newly Renovated Office 2Health News:RSCNJ Is Celebrating the Reopening of Their Newly Renovated Office 3Health News:Hip Resurfacing at Texas Orthopedics Enables Patient to Climb Mt. Kilimanjaro 2Health News:Hip Resurfacing at Texas Orthopedics Enables Patient to Climb Mt. Kilimanjaro 3
... that break down pollutants do their job and then ... wastes. Research was conducted on those bacteria by cornell ... ethenogenes, discovered in Ithaca sewage sludge in 1997 by ... and isolated and studied by Stephen Zinder, Cornell professor ...
... wine halved in France since the 1950s, the world's number ... its saviour. But while the Chinese and Indians have ... worlds largest, there are those attending the two-yearly event who ... margins in China are not there. It is not ready ...
... New England Journal of Medicine,treating hepatitis B patients with the ... with HIV to become resistant to two of the most ... researchers reported that a patient infected with both hepatitis B ... strain of HIV that is resistant to the antiviral drugs ...
... first human trial of a locally-made H5N1 bird flu vaccine as ... officials in the communist country. The drug trial, to be ... of several global efforts to develop a vaccine for mass production, ... Asia. ,The news comes as a new wave of ...
... Boffins at the Scripps Research Institute have found in ... pleiotrophin (PTN) plays in accelerating breast cancer . ... in breast cancer had not been clearly established, and ... to a better understanding of the molecular pathogenesis of ...
... prostitute might have led Hitler to orchestrate the genocidal ... ,Hitler might have contracted syphilis, which, possibly untreated, ... Jews and the mentally retarded. ,There is ... Dr Bassem Habeeb. ,Dr Habeeb said that ...
Cached Medicine News:Health News:Insilico Studies on Chlorine Eating Bacteria 2Health News:Go for Russia, Not China, Wine Experts Say 2Health News:Go for Russia, Not China, Wine Experts Say 3Health News:Challenges in Entecavir Drug Treatment 2Health News:Vietnam Plans Human Trial of Bird Flu Vaccine 2Health News:Researchers Have Found the Role of Protein in Accelerating Breast Cancer Progression 2Health News:Researchers Have Found the Role of Protein in Accelerating Breast Cancer Progression 3Health News:Hitler's Holocaust may Have Stemmed from Syphilis from Jewish Prostitute 2
(Date:2/26/2015)... -- The report, "Bottled Water Processing ... Blow molder, Shrink wrapper), Technology (RO, UF, MF, ... Region - Trends & Forecasts to 2019", published ... processing market with analyses and projection of the ... also identifies the driving and restraining factors for ...
(Date:2/26/2015)... , Feb. 26, 2015 People ... have the opportunity to participate in research that ... the first independent U.S. psoriasis registry begins recruiting ... joint collaboration with the National Psoriasis Foundation and ... reporting for secukinumab, a new biologic medication by ...
(Date:2/26/2015)... DIEGO , Feb. 26, 2015  MEI Pharma, Inc. ... the clinical development of novel therapies for cancer, announced today ... Executive Officer, will present at the Cowen and Company 35 ... 2015 at 10:40 a.m. Eastern time from the Boston Marriott ... accessed at www.meipharma.com . A replay will be available ...
Breaking Medicine Technology:Bottled Water Processing Market Worth $2,106.5 Million by 2019 2Bottled Water Processing Market Worth $2,106.5 Million by 2019 3Bottled Water Processing Market Worth $2,106.5 Million by 2019 4First independent U.S. psoriasis registry will track drug safety and effectiveness 2First independent U.S. psoriasis registry will track drug safety and effectiveness 3MEI Pharma to Present at Cowen and Company Health Care Conference 2MEI Pharma to Present at Cowen and Company Health Care Conference 3
... IRVINE, Calif., Nov. 16, 2010 Uptake Medical ... interventional emphysema therapy , announced today that J.C. ... and chief financial officer. MacRae comes to ... medical specialty device and biopharmaceutical product industries. He most ...
... Inc. (NYSE: PFE ) today announced ... Innovation, an entrepreneurial network of partnerships with leading ... by accessing leading translational researchers.  The University of ... the network. (Logo: http://photos.prnewswire.com/prnh/20100416/PFIZERLOGO) ...
Cached Medicine Technology:Uptake Medical Names J.C. MacRae as Chief Financial Officer 2Pfizer Launches Global Centers for Therapeutic Innovation, a Network of Research Partnerships, With University of California, San Francisco 2Pfizer Launches Global Centers for Therapeutic Innovation, a Network of Research Partnerships, With University of California, San Francisco 3Pfizer Launches Global Centers for Therapeutic Innovation, a Network of Research Partnerships, With University of California, San Francisco 4
Inquire...
... intensity ,Smaller slot surface area results ... ,Small slot dimensions require less sample ... ,More intense signal generated with the slot-blotter allows ... Accepts all types of transfer membranes ...
... The Minifold I system consists of four basic ... plenum, and metal clamping plate (see diagram). The ... for producing spots, dots, or slots (see below). ... purchased as an accessory plate in conjunction with ...
... The Minifold I system consists of four ... vacuum plenum, and metal clamping plate (see diagram). ... configurations for producing spots, dots, or slots (see ... be purchased as an accessory plate in conjunction ...
Medicine Products: