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Rutgers biomaterial debuts in clinical trials of new stent
Date:10/18/2007

ions to create a significant advance in stent technology, said Dr. Robert Schultz, REVAs president. This approach has allowed for us to bring it to the clinical stage quickly.

Our unconventional discovery process integrates combinatorial polymer libraries, high-throughput testing and computational modeling. This results in a much faster path to prototype development and a reduction in the cost and risk associated with the use of new, proprietary biomaterials, said Kohn, a Board of Governors Professor who directs the New Jersey Center for Biomaterials at Rutgers.

Michael J. Pazzani, vice president for research and graduate and professional education at Rutgers, spoke of the impact of Kohns work on the medical device industry. In addition to REVA, Rutgers has licensed the portfolio of Kohns patents to several other companies. One licensee was able to obtain FDA clearance for a new hernia repair device using one of Kohns polymers on a three-year track from concept to FDA market clearance, Pazzani said. Another is working with Kohn's combinatorial discovery process to identify an ideal polymer for their ophthalmic drug delivery device.

The significance of Kohns work is related to its general applicability to many different biomaterials design challenges as evidenced by the diversity of products being commercialized using this discovery process.

The scientific foundations of the new biomaterials discovery process are being developed with support to the New Jersey Center for Biomaterials and the Kohn Laboratory from the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health.

In collaboration with REVA, Kohn and his colleagues developed a polymer that is exceptionally strong and highly suitable for stent applications. In addition, the material was designed to be radio-opaque so it is X-ray visible, a property critical to the proper placement of the stent in the artery. It is also bi
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Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x652
Rutgers, the State University of New Jersey
Source:Eurekalert

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