Navigation Links
Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?
Date:3/13/2008

Surgery is the only curative treatment in patients with bile duct cancer. To develop a therapeutic concept a reliable diagnostic procedure is of great importance in these patients. Due to longitudinal tumor growth along the bile duct, imaging techniques including ultrasound, computed tomography, and magnetic resonance imaging are of limited sensitivity for the detection of bile duct cancer. Brush cytology and/or forceps biopsy during endoscopy are routinely used for distinction between benign bile duct stricture and bile duct cancer. The current study was designed to address the question of diagnostic sensitivity for brush cytology and forceps biopsy in a homogeneous patient group with bile duct cancer.

This research, performed by a team led by Prof. Dr. Christian Prinz and his colleagues, is described in a research article to be published in the February 21, 2008 issue of the World Journal of Gastroenterology.

In 41.4% of patients, positive results for malignancy were obtained using brush cytology and in 53.4% of patients positive results were obtained using forceps biopsy. The combination of both techniques resulted in only a minor increase in diagnostic sensitivityup to 60.3%. Overall, in 23 out of 58 patients, definitive diagnosis could not be achieved using the combination of brush cytology and forceps biopsy.

In the view of the authors the results for routinely used diagnostic approaches in patients with bile duct cancer are disappointing. Therefore, additional diagnostic techniques should be evaluated and should become routine in patients with negative cytological and histological findings.

Further research should clarify diagnostic utility of new diagnostic approaches such as modern molecular markers for bile duct cancer.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
2. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
3. The ScottCare Corporation Completes Acquisition of Rozinn Electronics, a Leading Manufacturer of Cardiac Diagnostic Products
4. Quest Diagnostics to Speak at the Bear Stearns Healthcare Conference
5. Pathway Diagnostics Announces Commercial Availability of SensiTrop(TM) HIV Co-receptor Tropism Assay
6. Hypertension Diagnostics Announces Fiscal Year 2007 Results
7. Foundation Venture Capital Group, LLC Invests in Start Up Committed to Breast Cancer Diagnostics
8. Meretek Diagnostics and Otsuka America Pharmaceutical, Inc. Announce Completion of Merger
9. Siemens Medical Solutions Diagnostics Announces the Release of the Rapidlab 1200 Series Version 2.0 Software
10. Aloka to Unveil New ProSound Diagnostic Ultrasound System at the 17th World Congress on Ultrasound in Obstetrics and Gynecology, 7th to 11th of October 2007 in Florence, Italy
11. New peritoneal dialysis diagnostic discovered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... ... May 04, 2016 , ... ... support for knees, ankles, and elbows. Engineered with athletes in mind, OMNIFORCE ... manufacturing (opposed to ineffective circular knitting, common in the industry) produces premium ...
(Date:5/4/2016)... ... May 04, 2016 , ... With the stamp of approval from the ... May as National Cancer Research Month. According to the American Cancer Society (2016) ... predications of one in four Americans dying as a result. , With numbers as ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... Group is scheduled on July 25-27, 2016 at Las Vegas. It aims to ... professionals from educational institutes and research organizations across the globe; making the conference ...
(Date:5/3/2016)... ... May 04, 2016 , ... An accurate ... reaching the global health community through expanding activities that embrace training, standards, technology ... the resource-limited countries. , In support of this important work, ASCP ...
(Date:5/3/2016)... ... 03, 2016 , ... In April, Amerec launched a new website designed with ... the best steam and sauna solutions. , First, the Amerec website has been redesigned ... all of the site’s features, especially the Steam Builder Tool , to both ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... May 3, 2016 ... dass sie einen entscheidenden Meilenstein durch diese ... Aufruf zum Handeln, um Patientenresultate  bei Verdauungs- ... zu Fortschritten im Verständnis der Hepatischen Enzephalopathie ... Bewusstsein für Hepatische Enzephalopathie in der Öffentlichkeit ...
(Date:5/2/2016)... May 2, 2016  While nearly three-quarters of Americans ... have on their health, only about half report taking ... the results of a new survey announced today by ... start of National Osteoporosis Month, Hologic is raising awareness ... nearly 56 million Americans. Osteoporosis is a ...
(Date:4/29/2016)... , April 29, 2016 ... Review, H1 2016" market research report that provides ... with comparative analysis at various stages, therapeutics assessment ... of administration (RoA) and molecule type, along with ... It also reviews key players involved in the ...
Breaking Medicine Technology: