Navigation Links
Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?
Date:3/13/2008

Surgery is the only curative treatment in patients with bile duct cancer. To develop a therapeutic concept a reliable diagnostic procedure is of great importance in these patients. Due to longitudinal tumor growth along the bile duct, imaging techniques including ultrasound, computed tomography, and magnetic resonance imaging are of limited sensitivity for the detection of bile duct cancer. Brush cytology and/or forceps biopsy during endoscopy are routinely used for distinction between benign bile duct stricture and bile duct cancer. The current study was designed to address the question of diagnostic sensitivity for brush cytology and forceps biopsy in a homogeneous patient group with bile duct cancer.

This research, performed by a team led by Prof. Dr. Christian Prinz and his colleagues, is described in a research article to be published in the February 21, 2008 issue of the World Journal of Gastroenterology.

In 41.4% of patients, positive results for malignancy were obtained using brush cytology and in 53.4% of patients positive results were obtained using forceps biopsy. The combination of both techniques resulted in only a minor increase in diagnostic sensitivityup to 60.3%. Overall, in 23 out of 58 patients, definitive diagnosis could not be achieved using the combination of brush cytology and forceps biopsy.

In the view of the authors the results for routinely used diagnostic approaches in patients with bile duct cancer are disappointing. Therefore, additional diagnostic techniques should be evaluated and should become routine in patients with negative cytological and histological findings.

Further research should clarify diagnostic utility of new diagnostic approaches such as modern molecular markers for bile duct cancer.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
2. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
3. The ScottCare Corporation Completes Acquisition of Rozinn Electronics, a Leading Manufacturer of Cardiac Diagnostic Products
4. Quest Diagnostics to Speak at the Bear Stearns Healthcare Conference
5. Pathway Diagnostics Announces Commercial Availability of SensiTrop(TM) HIV Co-receptor Tropism Assay
6. Hypertension Diagnostics Announces Fiscal Year 2007 Results
7. Foundation Venture Capital Group, LLC Invests in Start Up Committed to Breast Cancer Diagnostics
8. Meretek Diagnostics and Otsuka America Pharmaceutical, Inc. Announce Completion of Merger
9. Siemens Medical Solutions Diagnostics Announces the Release of the Rapidlab 1200 Series Version 2.0 Software
10. Aloka to Unveil New ProSound Diagnostic Ultrasound System at the 17th World Congress on Ultrasound in Obstetrics and Gynecology, 7th to 11th of October 2007 in Florence, Italy
11. New peritoneal dialysis diagnostic discovered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in ... ways they remain in the eye of the beholder, according to experts who offered ... The American Journal of Managed Care. For the full issue, click here . ...
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/26/2016)... NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and ... to be personalized through a fitness app. The fitness app plans to fix the two ... currently only offer a one size fits all type program , They don’t ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... ... ... of Bruton Memorial Library on June 21 due to a possible lice infestation, as reported ... head lice: the parasite’s ability to live away from a human host, and to infest ... in the event that lice have simply gotten out of control. , As lice are ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of ... Farma Brasil as the company,s second affiliate in Latin America . ... ... Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: