Navigation Links
Routine evaluation of prostate size not as effective in cancer screening, Mayo study finds
Date:11/10/2009

ROCHESTER, Minn. -- New Mayo Clinic research studied the association between prostate-specific antigen (PSA) levels and prostate size and found that routine annual evaluation of prostate growth is not necessarily a predictor for the development of prostate cancer. However the study suggests that if a man's PSA level is rising quickly, a prostate biopsy is reasonable to determine if he has prostate cancer. These findings are being presented this week at the North Central Section of the American Urological Association (http://www.ncsaua.org/) in Scottsdale, Ariz.

VIDEO ALERT: Additional audio and video resources are available on the Mayo Clinic News Blog (http://newsblog.mayoclinic.org/2009/11/09/routine-prostate-size-evaluation-not-as-effective-in-cancer-screening/).

These Mayo Clinic study findings were based on data in the Olmsted County Study of Urinary Health Status among Men, a large cohort study of men living in Olmsted County, Minn. Researchers randomly selected 616 men between the ages of 40 and 79 who did not have prostate disease. Patients participated in examinations every two years for 17 years, which included PSA and prostate volume measurements using ultrasound, to determine changes in prostate disease.

"One of the major advantages of this large cohort study is that the men have participated in this study for over 17 years," says Rodney Breau, M.D., a Mayo Clinic urologic oncology fellow who led the study. Because of this, we have the ability to look at long-term relationships between prostate growth, change in PSA and development of prostate cancer."

Of the 616 men, 58 (9.4 percent) developed prostate cancer. Men who were diagnosed with prostate cancer had a faster rise in PSA levels (6 percent/year) compared to men who were not diagnosed with cancer (3.3 percent/year). However, the increase in prostate size was similar between these two groups (median change of 2.2 percent/year).

PSA is a substance produced in the prostate gland. Normally, a small amount of PSA enters the bloodstream. A higher amount of PSA or an abrupt rise in PSA levels can indicate a problem, possibly cancer.

"The question we're trying to answer is, if we see a man with a rising PSA level, could this change in PSA be explained by a proportional increase in prostate size?" says Dr. Breau. "Our data indicate that men with or without prostate cancer have similar rates of prostate growth. If a man's PSA is quickly rising, he likely deserves a prostate biopsy to determine if he has prostate cancer. Assessment of change in prostate size should not influence the decision to biopsy."


'/>"/>

Contact: Amy Tieder
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. CDC Panel Says No to Routine Use of Gardasil for Boys
2. Study questions need for routine intervention in patients with renovascular disease
3. National Health Care Reformers Should Pay Attention to Lawsuit Alleging that Nations Largest Insurer Routinely Denies Liver Transplants
4. Back to School Season is Time for New Green Routines
5. Routine Testing Would Improve Herceptin Use in Breast Cancer
6. Make Eye Exams Part of the Back to School Routine
7. Dr. Donnica Moore Advocates that Women Follow a Preventive Dental Health Routine that Includes Crest Pro-Health Enamel Shield
8. On HIV Testing Day, HIVMA calls for health care reform to make testing routine every day
9. Kay Renz PR to Workout Publicity Routine for Adriana Martin, Founder of Fit Mom For Life
10. Hispanics Placing Their Oral Health at Risk by Cutting Back on Routine Dental Care
11. Institution of a bedtime routine improves sleep in infants and toddlers, maternal mood
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2017)... ... July 24, 2017 , ... Cheerag D. Upadhyaya , ... Marion Bloch Neuroscience Institute (SLMBNI), part of Saint Luke’s Health System . ... , Cheerag D. Upadhyaya, MD. M.Sc., FAANS joins Stanley P. Fisher, M.D., ...
(Date:7/24/2017)... ... July 24, 2017 , ... BayMark Health Services ... Health Services Administration’s (SAMHSA) State Targeted Response to the Opioid Crisis program. ... will facilitate the development of a hub and spoke model for opioid treatment ...
(Date:7/24/2017)... ... July 24, 2017 , ... Peruvian Ayahuasca retreat, ... be awarded annually to and divided between two full-time university students enrolled in ... Amazonian plant medicine. To apply for the scholarship, students are asked to submit ...
(Date:7/24/2017)... ... July 24, 2017 , ... Axiad IDS , a leading provider ... partnered with WALLIX to expand its solution to help government contractors more ... a number of ways to address the authentication requirements within NIST SP800-171, but ...
(Date:7/24/2017)... ... 24, 2017 , ... A CDC study shows that, although people are taking more steps to ... 29), had at least one case of sunburn within the past year. It’s common and ... ignore the issue. However, only recently have people become conscientious of the risks that accompany ...
Breaking Medicine News(10 mins):
(Date:7/20/2017)... -- Prime Therapeutics LLC (Prime) released this statement from its Chief ... for Clinical and Economic Review,s (ICER) public meeting ... of abuse-deterrent formulations (ADF) of opioids. Prime was the sole ... "The ICER data ... use of abuse-deterrent formulations (ADF) in opioids in terms of ...
(Date:7/14/2017)... It should come as no surprise to anyone that ... of a crippling opioid epidemic. According to the Center ... deaths from opiate-based medications has quadrupled, Says, Dr. David ... 2001 to 2015". During this time, the prescription rate for ... a compelling link between prescription and eventual addiction. The problem ...
(Date:7/12/2017)... , July 12, 2017  Eli Lilly and Company (NYSE: ... with generic companies to resolve pending patent litigation in the ... Virginia regarding the Cialis ® (tadalafil) unit ... April 26, 2020. As part of the agreement, Cialis exclusivity ... 27, 2018. "The unit dose patent for Cialis ...
Breaking Medicine Technology: