Navigation Links
Routine Evaluation of Prostate Size Not as Effective in Cancer Screening, Mayo Study Finds
Date:11/10/2009

ROCHESTER, Minn., Nov. 10 /PRNewswire-USNewswire/ -- New Mayo Clinic research studied the association between prostate-specific antigen (PSA) levels and prostate size and found that routine annual evaluation of prostate growth is not necessarily a predictor for the development of prostate cancer. However the study suggests that if a man's PSA level is rising quickly, a prostate biopsy is reasonable to determine if he has prostate cancer. These findings are being presented this week at the North Central Section of the American Urological Association (http://www.ncsaua.org/) in Scottsdale, Ariz.

(Logo: http://www.newscom.com/cgi-bin/prnh/20090105/MAYOLOGO)

VIDEO ALERT: Additional audio and video resources are available on the Mayo Clinic News Blog (http://newsblog.mayoclinic.org/2009/11/09/routine-prostate-size-evaluation-not-as-effective-in-cancer-screening/).

These Mayo Clinic study findings were based on data in the Olmsted County Study of Urinary Health Status among Men, a large cohort study of men living in Olmsted County, Minn. Researchers randomly selected 616 men between the ages of 40 and 79 who did not have prostate disease. Patients participated in examinations every two years for 17 years, which included PSA and prostate volume measurements using ultrasound, to determine changes in prostate disease.

"One of the major advantages of this large cohort study is that the men have participated in this study for over 17 years," says Rodney Breau, M.D., a Mayo Clinic urologic oncology fellow who led the study. "Because of this, we have the ability to look at long-term relationships between prostate growth, change in PSA and development of prostate cancer."

Of the 616 men, 58 (9.4 percent) developed prostate cancer. Men who were diagnosed with prostate cancer had a faster rise in PSA levels (6 percent/year) compared to men who were not diagnosed with cancer (3.3 percent/year). However, the increase in prostate size was similar between these two groups (median change of 2.2 percent/year).

PSA is a substance produced in the prostate gland. Normally, a small amount of PSA enters the bloodstream. A higher amount of PSA or an abrupt rise in PSA levels can indicate a problem, possibly cancer.

"The question we're trying to answer is, if we see a man with a rising PSA level, could this change in PSA be explained by a proportional increase in prostate size?" says Dr. Breau. "Our data indicate that men with or without prostate cancer have similar rates of prostate growth. If a man's PSA is quickly rising, he likely deserves a prostate biopsy to determine if he has prostate cancer. Assessment of change in prostate size should not influence the decision to biopsy."

Other Mayo Clinic researchers involved in this study include: R. Jeffrey Karnes, M.D. (http://www.mayoclinic.org/bio/12463493.html); Debra Jacobson; Michaela McGree; Steven Jacobsen, M.D., Ph.D.; Ajay Nehra, M.D. (http://www.mayoclinic.org/bio/12370606.html); Michael Lieber, M.D.(http://www.mayoclinic.org/bio/10203567.html); and Jennifer St. Sauver, Ph.D.

To request an appointment at Mayo Clinic, please call 480-422-1490 for the Arizona campus, 904-494-6484 for the Florida campus, or 507-216-4573 for the Minnesota campus.

About Mayo Clinic

Mayo Clinic is the first and largest integrated, not-for-profit group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,700 physicians, scientists and researchers and 50,100 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn.; Jacksonville, Fla.; and Scottsdale/Phoenix, Ariz. Collectively, the three locations treat more than half a million people each year. To obtain the latest news releases from Mayo Clinic, go to www.mayoclinic.org/news. For information about research and education, visit www.mayo.edu. MayoClinic.com (www.mayoclinic.com) is available as a resource for your health stories.

SOURCE Mayo Clinic


'/>"/>
SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Routine evaluation of prostate size not as effective in cancer screening, Mayo study finds
2. CDC Panel Says No to Routine Use of Gardasil for Boys
3. Study questions need for routine intervention in patients with renovascular disease
4. National Health Care Reformers Should Pay Attention to Lawsuit Alleging that Nations Largest Insurer Routinely Denies Liver Transplants
5. Back to School Season is Time for New Green Routines
6. Routine Testing Would Improve Herceptin Use in Breast Cancer
7. Make Eye Exams Part of the Back to School Routine
8. Dr. Donnica Moore Advocates that Women Follow a Preventive Dental Health Routine that Includes Crest Pro-Health Enamel Shield
9. On HIV Testing Day, HIVMA calls for health care reform to make testing routine every day
10. Kay Renz PR to Workout Publicity Routine for Adriana Martin, Founder of Fit Mom For Life
11. Hispanics Placing Their Oral Health at Risk by Cutting Back on Routine Dental Care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... ... June 28, 2017 , ... Drs. Steven Crandall, Karen Johnson ... in Pittsburgh, PA, and Upper St. Clair, PA, without a referral. The doctors address ... the health of the temporomandibular joint and facial muscles that support it. , ...
(Date:6/28/2017)... ... , ... Eating disorders have the highest mortality rate of any mental illness ... as a direct result from an eating disorder in the U.S. As the rate ... Foundation meets this challenge by offering what has become the leading certification program for ...
(Date:6/28/2017)... ... June 28, 2017 , ... Park Systems , a leader in Atomic ... SEMICONWest attendees and Park customers on July 11, 2017 from 12-2pm at the ... Chairman & CEO of Park Systems, and Prof. Krishna Saraswat , Rickey/Nielsen Professor ...
(Date:6/28/2017)... ... June 28, 2017 , ... Designers Insurance Agency, ... in northern Virginia and DC, is announcing a cooperative charity event in conjunction ... and other disorders that lead to memory impairment. , The Insight Memory Care ...
(Date:6/27/2017)... ... June 27, 2017 , ... DrugDev understands that ... they can trust the sponsor to pay them correctly and on time. As the ... establish payment strategies that encourage sites to work on their studies. , At a ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... BELL, Pa. , June 1, 2017 ... (PRN) and Veterinarian Recommended Solutions (VRS), and KD Pharma ... investment in Nutriceutical Holdings by KD Pharma Group. KD ... Holdings with the option to acquire the entire company. ... partner in KD. They are committed to growing the ...
(Date:5/30/2017)... AVIV, Israel , May 30, 2017 ... stage pharmaceutical Company specializing in the development of ... will present a company overview at three upcoming ... The 7th Annual LD Micro Invitational: ... Date:                     ...
(Date:5/26/2017)... May 25, 2017  In response to the opioid ... Direct Relief is working with Pfizer to make up ... no cost to community health centers, free and charitable ... "Pfizer has a long-standing commitment to ... ensuring patient safety through educational activities," said Caroline ...
Breaking Medicine Technology: