Navigation Links
Roundworm could provide new treatment for sepsis
Date:3/8/2011

Research by the University of Liverpool has found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in a type of roundworm.

Sepsis is a serious inflammatory condition, caused by the body over-reacting to infection. The body becomes overwhelmed by bacteria, setting off a series of reactions that lead to inflammation and clotting. It affects around 20 million people worldwide each year, and accounts for a large proportion of intensive care unit admissions.

For the past 30 years, sepsis has largely been treated by antibiotics and maintenance of blood flow. Despite these treatments - often complicated by antibiotic-induced liver injury or the presence of multi drug-resistant bacteria - mortality rates for those with severe illness who go into multi-organ damage and septic shock, remain as high as 50%. New treatments for septic shock are of high clinical need.

Findings by an international team, led by Professor Alirio Melendez, based at the University's Medical Research Council Centre for Drug Safety Science in the Institute of Translational Medicine, show that inflammation triggered by bacterial endotoxins in immune cells from patients with sepsis is suppressed by a protein called ES-62 which is secreted by a type of roundworm called Acanthocheilonema viteae.

Roundworms can infect the human digestive tract, lymphatic vessels, skin and muscle. They are extremely common - particularly in parts of the world with poor sanitation - and it is estimated that nearly a quarter of the world's population are currently infected. Roundworm can live in the human body for decades without adverse effects or triggering the immune system.

Scientists already know that the protein secreted by roundworm is capable of suppressing inflammation and people infected with worms usually benefit from reduced inflammation if they suffer from conditions such as allergies and autoimmune diseases.<
'/>"/>

Contact: Kate Spark
kate.spark@liv.ac.uk
0044-151-794-2247
University of Liverpool
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Bone-creating protein could improve dental implant success
2. Student innovation at Rensselaer Polytechnic Institute could lead to better breast cancer screening
3. Latest findings of Dartmouth HIV/AIDS study could turn treatment on its head
4. New report says large proportion of colorectal cancer deaths could be prevented
5. Simple blood test at discharge could help reduce hospital readmissions for heart failure patients
6. Stupid strategies could be best for the genes
7. Higher Vitamin D Intake Could Cut Cancer Risk
8. A North American first at the Montreal Heart Institute could help treat thousands of Canadians
9. Redesign of US donor-liver network could boost transplants by several hundred per year
10. High vitamin-D bread could help solve widespread insufficiency problem
11. MIT engineers design new nanoparticle that could lead to vaccines for HIV, malaria, other diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... 24, 2014 Mental health issues ... They break up families, ruin careers, and generally ... for those that suffer,” says Hardy Nutritionals® ... showing that our specialized nutritional treatments can reverse ... on “Mind Over Matter”, the premiere episode of ...
(Date:11/24/2014)... (PRWEB) November 24, 2014 Dr. Michael ... Fertility Center, recently appeared on NBC to discuss egg freezing ... freezing has been trending in the news recently, with new ... procedure for women. , “[The companies] see it ... are on a career hot path.” Says Dr. Kettel. , ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 The ... Market 2006 to 2020 - Asia-Pacific” provides quantitative ... devices market segments: minimally invasive body contouring devices, ... The analysis includes market size data by revenue ... the following countries: China, Japan, South Korea, Australia ...
(Date:11/23/2014)... (HealthDay News) -- The holidays can be a challenge ... can trigger major meltdowns, an expert says. "Holidays ... circumstances, but when you have children with special needs, ... therapy professor at University of the Sciences in Philadelphia, ... to let your hosts or visitors know what special ...
(Date:11/23/2014)... York, NY (PRWEB) November 23, 2014 ... the past month in a federal litigation involving Byetta ... similar diabetes medications, Bernstein Liebhard LLP reports. , ... 566 claims over a class of Type 2 diabetes ... filed in the U.S. District Court, Southern District of ...
Breaking Medicine News(10 mins):Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 2Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 3Health News:Dr. Michael Kettel of San Diego Fertility Center Gives “An Inside Look at Freezing Eggs” on NBC 2Health News:Dr. Michael Kettel of San Diego Fertility Center Gives “An Inside Look at Freezing Eggs” on NBC 3Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 2Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 3Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 4Health News:Holidays Can Be Sensory Overload for Kids With Autism 2Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 2Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 3Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 4
... PHILADELPHIA, Dec. 24 Congressman Chaka Fattah (D-PA) releases the ... reform legislation: , "Senate Democrats deserve our thanks and ... to do, but I am confident that the House and ... the new year we will be sending President Obama a ...
... Today, The U.S. Conference of Mayors (USCM) congratulates the U.S. Senate ... millions of the uninsured. In a historic Christmas Eve session, ... Protection and Affordable Care Act. , "Not since 1963, has ... It is appropriate the most important piece of health ...
... cells generate embryonic-like cells, study finds , THURSDAY, Dec. 24 ... fight the common cold and heal wounds, but the antioxidant ... generate embryonic-like stem cells, new research suggests. , The ... Stem Cell , add to previous research that showed how ...
... , WASHINGTON, Dec. 24 "The Senate,s historic vote ... creation of a transformational national long-term services and supports insurance ... people with disabilities. The Senate bill also includes means by ... acute and long-term problems. It will stimulate innovation in ...
... , , WASHINGTON, Dec. ... critical that this step be accomplished as we continue our journey ... committed to working with Congress to ensure health insurance reform is ... Delgado, President and CEO of the National Alliance for Hispanic Health, ...
... of the Bipartisan Policy Center Report Continue to Encourage Joint ... U.S. Senate Majority Leaders Howard Baker, Tom Daschle and Bob ... and Leaders, Project on the State of American Health Care, ... and Affordable Care Act of 2009 today. , ...
Cached Medicine News:Health News:Senate Action Part of Long Road to Health Care Reform 2Health News:Former Senate Majority Leaders Baker, Daschle and Dole Commend Senate Passage of Health Care Bill 2Health News:Former Senate Majority Leaders Baker, Daschle and Dole Commend Senate Passage of Health Care Bill 3
(Date:11/22/2014)... Research and Markets  has announced the addition ... 2014-2017" report to their offering. ... protein drug market has been expanding rapidly owing to ... like. During 2005-2013, sales of recombinant protein drugs available ... 19.1%, and it is projected that ...
(Date:11/21/2014)... CORONA, Calif. and VIENNA, Va. ... an innovative in-home care provider that operates in ... with BeClose, a leading provider of remote caregiving technology. Alta ... new and existing client receiving homecare services. ... believe this technology is the key to providing the ...
(Date:11/21/2014)... , Nov. 21, 2014  World Hemp Oil, an ... THC, announces they are now offering legal, organic oil ... Web type strains grown in medical marijuana states. People ... disorders, such as Parkinson,s, MS, and spinal cord injury, ... to pass, because imported CBD Oil Is legal in ...
Breaking Medicine Technology:China Recombinant Protein Drug Industry Report, 2014-2017 2China Recombinant Protein Drug Industry Report, 2014-2017 3Alta Home Care, Inc. and BeClose Partner to Enable Seniors to Remain in Their Homes Safely and Securely 2New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 2New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 3
... N.J., Dec. 9, 2011  Saint-Gobain Performance Plastics has upgraded ... new state-of-the art laser engraving system. The system ... or tag of all hose assemblies, piping and ... Saint-Gobain Performance Plastics can engrave crimp collars on ...
... 2011 Gen-Probe Incorporated (NASDAQ: GPRO ) announced today ... Conference in New York on December 14, 2011 at approximately 10:15 ... and may be accessed through a link on the investors section ... available for 30 days following the event. ...
Cached Medicine Technology:Saint-Gobain Introduces Laser Engraving for Hose Assemblies 2Gen-Probe to Webcast Presentation at the Oppenheimer 22nd Annual Healthcare Conference 2
Inquire...
Inquire...
Inquire...
... a range of 18 Ophthalmic frames ... and producted to the very hightest ... super lightweight Titanium and Beta Titanium ... host of beautifully formed and innovative ...
Medicine Products: