Navigation Links
Rotigotine Skin Patch May Ease Restless Legs Symptoms
Date:5/30/2008

But one expert notes problems with manufacturing, unreliable delivery of the drug

FRIDAY, May 30 (HealthDay News) -- Skin patches that contain the drug rotigotine help relieve restless legs syndrome (RLS), according to a German study.

Dopaminergic drugs -- which stimulate the body's dopamine system -- are currently used as a first-line treatment for RLS, and rotigotine is already used to treat Parkinson's disease. This study of 458 people with moderate to severe RLS examined the efficacy of rotigotine skin patches.

The patients were randomly assigned to apply skin patches with 1 milligrams of rotigotine (115 patients), 2 milligrams (112), or 3 milligrams (114) once a day for six months. A fourth group of 117 patients received a placebo.

The patients were assessed using the International Restless Leg Syndrome study group severity rating scale (IRLS) and the clinical global impressions (CGI) item 1 score, which measures severity of symptoms. At the start of the study, the patients' average IRLS score was 28.1, and their average CGI item 1 score was four or more.

At the end of the study, mean changes in IRLS score were: -13.7 in the 1 mg group; -16.2 in the 2 mg group; -16.8 in the 3 mg group; and -8.6 in the placebo group. Changes in the CGI item 1 score were: -2.09 in the 1 mg group; -2.41 in the 2 mg group; -2.55 in the 3 mg group; and -1.34 in the placebo group.

Of the 341 patients who used the rotigotine skin patches, 145 (43 percent) experienced skin reactions (mostly mild or moderate), compared to two of 117 (2 percent) of those who received the placebo.

Ten patients suffered serious side effects related to rotigotine: elevation of liver enzymes (1 patient); worsening of tinnitus (1); non-response to anticoagulation (1); electrocardiogram changes (1); and skin patch application site reactions (6). All the skin reactions resolved within a short time after the patch was removed.'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Patch Form of HRT Poses Less Clotting Risks Than Pill Does
2. The First QPatch HT in China Placed in WuXi PharmaTech (NYSE: WX)
3. Iomai Wins Department of Defense Grant to Develop a Stable, Patch-Based Anthrax Vaccine
4. Study Finds Single Dose of Iomai Patch With Pandemic Flu Vaccine Achieves Protective Levels
5. Mylan Confirms Its Matrix Design Fentanyl Patch Is Not Included In the Widespread Recall Announced February 12th
6. PriCara(TM) Recalls 25 mcg/hr DURAGESIC(R) (fentanyl transdermal system) CII Pain Patches
7. Iomai Study Shows Self-Applied Travelers Diarrhea Vaccine Patch Comparable to Clinician-Applied Vaccine Patch
8. Ringing endorsement: Women prefer contraceptive ring over patch
9. FDA Warns Clot Risk Higher in Birth Control Patch Than Pill
10. FDA Renews Warnings on Pain-Relief Patch
11. Studies of 20,000 smokers show quit rates double with counseling and free nicotine patches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... NV (PRWEB) March 28, 2015 How ... is a growing field in orthopaedic medicine. While diagnostic ... tear to confirm the pain etiology, research presented today ... AOSSM ) Specialty Day suggests that pain relief from ... arthroscopic hip surgery. , “Our study looked to ...
(Date:3/28/2015)... 2015 Genomic medicine experts have sequenced ... for the first time, key information for understanding and ... the newly posted story on the Surviving Mesothelioma ... British Columbia, the British Columbia Cancer Agency, and PhenoPath ... underlying molecular alterations and mutations that can lead to ...
(Date:3/28/2015)... NE (PRWEB) March 28, 2015 ... in healthcare staffing, including physical therapy jobs, has ... at the Ohio Physical Therapy Association Annual Conference ... Renaissance Columbus Downtown Hotel in Columbus, OH. ... networking opportunities, and exhibits with products and services. ...
(Date:3/28/2015)... 28, 2015 Designers and Professionals of ... entitled Scratches 5K from Pixel Film Studios. , “Scratches ... any media inside Final Cut Pro X” Said Christina ... time and is an effective tool for any FCPX ... Scratches 5K's intuitive grunge overlays. Simply drag title layers ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 Servpro ... , this week released a report about the link ... of asthma sufferers, and according to recent medical research, ... , According to the Environmental Protection Agency, people with ... reactions. Breathing in mold may trigger asthma attacks for ...
Breaking Medicine News(10 mins):Health News:Pain Injections for Hip Arthroscopy Patients May Not Predict Surgical Outcomes 2Health News:New Genomics Research May Help Doctors Tailor Mesothelioma Treatment, According to Surviving Mesothelioma 2Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the Ohio Physical Therapy Association Annual Conference 2Health News:Pixel Film Studios Unveiled Scratches 5k for Final Cut Pro X Editors 2Health News:Water Damage Restoration Specialists Servpro of Paso Robles Release Report on Mold and Asthma 2Health News:Water Damage Restoration Specialists Servpro of Paso Robles Release Report on Mold and Asthma 3
... Children in the South Bay,suffering from asthma, acne, ... specialty care from Lucile Packard Children,s Hospital,physicians without ... Bay,Specialty Center in Los Gatos houses 13 sub-specialties ... of its parent institution. "We,re very excited," ...
... of remarks by President Bush, Senator Bob Dole and ... coming. Welcome to the Rose,Garden. I appreciate Senator Dole ... joining me today. Welcome. I just finished an ... -- with service members who were rebuilding their lives,after ...
... tenor expresses gratitude for successful treatment, SEATTLE, ... Leukemia Foundation has announced it will endow a ... Center in honor of E.,Donnall Thomas, M.D., who ... a strong wish to honor Carreras and Thomas,emeritus ...
... the U.S. Food and Drug,Administration,s (FDA,s) Cardiovascular ... majority of members voted to recommend the ... FOSRENOL(R),(lanthanum carbonate), to treat hyperphosphatemia (elevated levels ... disease (CKD) Stage 4 patients.,Currently, FOSRENOL is ...
... Leader Harry Reid and Senator Orrin Hatch were joined ... advocates at a,news conference this morning to urge Members ... Health Insurance Program. Below are,Pelosi,s opening remarks:, "Thank ... and to the,representatives of the many organizations that are ...
... Oct. 16 ReCellular, Inc., the world,s,foremost ... phones and,accessories, today announced it has entered ... http://www.consumercellular.com ), one of,the nation,s oldest and ... handsets for recycling from their customers across ...
Cached Medicine News:Health News:Packard Children's Hospital Opens New South Bay Specialty Clinic Bringing Specialty Care Close to Home 2Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 2Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 3Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 4Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 5Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 6Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 7Health News:Remarks by President Bush, Senator Bob Dole and Secretary Donna Shalala on Commission on Care for America's Returning Wounded Warriors Report Implementation 8Health News:Carreras Foundation to Endow Clinical-Research Chair at Fred Hutchinson Cancer Research Center 2Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 2Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 3Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 4Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 5Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 6Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 7Health News:Pelosi: In 48 Hours, Congress Must Choose Between Meeting the Needs of America's Children or Not 2Health News:ReCellular Named Exclusive Cell Phone Recycling Partner for Consumer Cellular 2Health News:ReCellular Named Exclusive Cell Phone Recycling Partner for Consumer Cellular 3
(Date:3/26/2015)... 2015 "Whether it,s our family, our friends, ... In a single sentence, Dr. Anthony Coyle ... Pfizer,s Centers for Therapeutic Innovation (CTI), sums ... at America,s biopharmaceutical companies. CTI,s unique ... patient foundations and the National Institutes of Health (NIH) ...
(Date:3/26/2015)... 2015 Cardiologists at Beaumont Hospital, ... commercial implant of a device recently approved by the ... fibrillation. The Watchman Left Atrial Appendage Closure implant is ... to reduce the risk of stroke. Atrial ... more than 5 million Americans. Twenty percent of all ...
(Date:3/26/2015)... , March 26, 2015 When ... by their existing PACS vendor their system would ... determined that they needed a better structured solution ... selected Avreo interWORKS due to its interface capabilities ... meaningful use standards through to the hospital,s radiology ...
Breaking Medicine Technology:Collaboration for Cures: Teaming Up to Advance Science and Save Lives 2Beaumont Hospital, Royal Oak among first to offer alternative to blood-thinning medications for atrial fibrillation 2Beaumont Hospital, Royal Oak among first to offer alternative to blood-thinning medications for atrial fibrillation 3Clinch Memorial Hospital Modernizes Workflow with Avreo interWORKS 2
... at Food and Drug Administration Meeting , ... WASHINGTON , July 20 ... and treating disease, representatives of the College of American Pathologists (CAP) ... increased oversight of laboratory developed tests (LDTs) and "direct-to-consumer" tests. Most ...
... SHENZHEN, China , July 20 /PRNewswire-Asia-FirstCall/ -- China Nepstar,Chain ... largest,drugstore chain in China based on the number of directly ... card. , , , ... Beginning in May 2010 , Nepstar started to expand its ...
Cached Medicine Technology:CAP Leaders Stress Need for Oversight of Direct-to-Consumer and Laboratory Developed Tests 2CAP Leaders Stress Need for Oversight of Direct-to-Consumer and Laboratory Developed Tests 3CAP Leaders Stress Need for Oversight of Direct-to-Consumer and Laboratory Developed Tests 4China Nepstar Chain Drugstore Provides Updates on Shopper's Card Program 2China Nepstar Chain Drugstore Provides Updates on Shopper's Card Program 3China Nepstar Chain Drugstore Provides Updates on Shopper's Card Program 4
... PalmScan P-2000 FastPach is an accurate, ... for glaucoma screenings. It works off ... makes charging of the device a ... screen controls make operating and viewing ...
The Cordis ANGIOGUARD Capture Guidewire is the first embolic protection device shown in clinical testing to achieve a relative stroke reduction of 70% during carotid stenting procedures....
... hand-held, point-of-care device for the qualitative detection of ... The TOX/See device can detect up to nine ... to 8 minutes and requires only a few ... packaged to maximize convenience and ease of use. ...
... 1-step, hand-held, point-of-care device for the qualitative detection ... The TOX/See device can detect up to ... 3 to 8 minutes and requires only a ... individually packaged to maximize convenience and ease of ...
Medicine Products: