Navigation Links
Rothman at Jefferson researchers show benefits of local anesthesia after knee replacement surgery

PHILADELPHIA Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.

Their research will be recognized with the Knee Society Award for the best work on a surgical technique at the American Academy of Orthopedic Surgeons annual meeting, February 7-11 in San Francisco. Their initial study findings will be presented on Friday, February 10th at 5:42 PM Pacific Time.

The randomized, double-blind trial administered either bupivacaine, a common analgesic, or normal saline intraoperatively through a catheter in the joint to 150 primary, unilateral knee replacement patients.

The catheters released fluid continually over two postoperative days. Patients were asked to complete questionnaires at 5 PM on the day of surgery and 8 AM and 5 PM each day until discharge, as well as at a four-week follow-up visit.

Patients who received bupivacaine reported receiving the least pain and the lowest narcotic consumption. There was also no significant different in postoperative complications.

The study concludes that knee replacement patients may positively benefit from intraarticular delivery of a local analgesic to decrease overall pain levels and reduce the need for opioids following surgery. With no noted increase in infection risk, intraarticular delivery may also provide an effective alternative for pain relief in the immediate postoperative time period without the disadvantages encountered with epidural anesthesia, regional nerve blockade and patient controlled analgesia pumps.

"This study opens up a potential new option for better pain management post-surgery for our knee replacement patients. Though further study is needed, these initial results are promising," says Nitin Goyal, MD, of the Rothman Institute at Jefferson, an author on the study.

Contact: Lee-Ann Landis
Thomas Jefferson University

Related medicine news :

1. Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI
2. Rothman at Jefferson research suggests abandon convention in diagnosing periprosthetic joint infection
3. Jefferson surgeon receives outstanding performance award from American College Of Surgeons
4. Jefferson physician named 2010 Emergency Department Director of the Year
5. Jefferson researcher receives 2010 Pancreatic Cancer Action Network-AACR Career Development Award
6. Clue to switch of bladder cancer from locally contained to invasive found by Jefferson scientists
7. Jefferson urologist awarded Lifetime Achievement Award from Endourological Society
8. CancerCare names Jefferson professor Physician of the Year
9. Jefferson study determines bone marrow stromal stem cells may aid in stroke recovery
10. Thomas Jefferson University professor elected AAAS Fellow
11. Jefferson clinical trial: Can a cholesterol drug prevent colon cancer?
Post Your Comments:
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
(Date:6/24/2016)... ... 2016 , ... EB Medicine presented its first-ever “Issue of ... in Ponte Vedra Beach, FL. The awards honor the outstanding work of leading ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the efforts ...
(Date:6/24/2016)... Maryland (PRWEB) , ... June 24, 2016 , ... ... Angels is actively feeding the Frederick area economy by obtaining investment capital for ... over the past 2½ years that have already resulted in more than a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
(Date:6/23/2016)... N.J. , June 23, 2016  Guerbet announced ... Premier Inc.,s Supplier Horizon Award . ... year, Guerbet was recognized for its support of Premier ... creation through clinical excellence, and commitment to lower costs. ... to receive this recognition of our outstanding customer service ...
Breaking Medicine Technology: