Navigation Links
Rothman at Jefferson research suggests abandon convention in diagnosing periprosthetic joint infection
Date:2/8/2012

PHILADELPHIA -- In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, while measuring a patients serum white blood cell count (WBC) and the percentage of neutrophils (PMN%), the conventional method for diagnosis, has a minimal role in the determination of PJI.

The synovial fluid is the viscous liquid that lubricates the joints and feeds the cartilage.

"This research indicates that we may need to reexamine how we diagnose PJI," said Javad Parvizi, MD, director of Research at the Rothman Institute and Professor of Orthopedics at Jefferson Medical College.

The study retrospectively examined 2,067 cases of revision hip or knee arthroplasty between 2004 and 2010. Of these, 961 cases had a diagnosis of PJI based on institutional criteria. Preoperative WBC counts and PMN numbers were examined at and found to be only 58.8 percent sensitive for infection and 62.2 percent specific for WBC; and 57 percent sensitive and 71 percent specific at the determined threshold of 7,650 cells/ml.

The results will be shared at the American Academy of Orthopedic Surgeons (AAOS) annual meeting on Wednesday, February 8th at 11:24 am Pacific Time.

Our study confirms the long held belief that serum white blood cell count and differential has minimal role in routine work-up of patients with suspected PJI, said Parvizi, an author on this influential study.


'/>"/>

Contact: Lee-Ann Landis
leeann.landis@jefferson.edu
215-955-2240
Thomas Jefferson University
Source:Eurekalert

Page: 1

Related medicine news :

1. Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI
2. Jefferson surgeon receives outstanding performance award from American College Of Surgeons
3. Jefferson physician named 2010 Emergency Department Director of the Year
4. Jefferson researcher receives 2010 Pancreatic Cancer Action Network-AACR Career Development Award
5. Clue to switch of bladder cancer from locally contained to invasive found by Jefferson scientists
6. Jefferson urologist awarded Lifetime Achievement Award from Endourological Society
7. CancerCare names Jefferson professor Physician of the Year
8. Jefferson study determines bone marrow stromal stem cells may aid in stroke recovery
9. Thomas Jefferson University professor elected AAAS Fellow
10. Jefferson clinical trial: Can a cholesterol drug prevent colon cancer?
11. Kimmel Cancer Center at Jefferson breast cancer symposium features latest in research, treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... September 20, 2017 , ... “Monique”: is the story of Monique, ... the creation of published author, Colleen Crispi, has owned four beauty salons and written ... involved in real estate and cooking. , “The doctor’s office was only three ...
(Date:9/19/2017)... ... 2017 , ... Only a few physicians were selected to receive the prestigious ... Clevens, MD, FACS . The founder and medical director of Clevens Face and ... at Yale, Harvard and the University of Michigan. He has served patients throughout Central ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... St. Vincent’s Infusion Services called, “PAPA Healthcare helps fill gaps, provide essential insights, ... enhanced service delivery and operations by leveraging PAPA Healthcare’s post-acute productivity and analytics ...
(Date:9/19/2017)... MD (PRWEB) , ... September 19, 2017 , ... ... Environmental Compliance and Safety for the President’s Malaria Initiative (PMI) Africa Indoor ... USAID’s Innovation to Action Award. , The Innovation to Action Award, a ...
(Date:9/19/2017)... ... 19, 2017 , ... The Lymphoma Research Foundation (LRF) – ... serving the lymphoma community through a comprehensive series of education programs, outreach initiatives ... national Swirl: A Wine Tasting Event series on Thursday, October 26, 2017. Hosted ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... 2017   PDI , a leader in infection ... an educational session focused on the role of chlorhexidine ... at the 2017 Annual Scientific Meeting of the Association ... at the Phoenix Convention Center ... 16-19, will also feature PDI,s Prevantics® Device Swab ...
(Date:9/5/2017)... 5, 2017  Xyntek Inc. has announced another milestone in their continued growth ... to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West Adams Street, Suite ... Xyntek's ... ...
(Date:9/1/2017)... Sept. 1, 2017 Michael Penna , ... , highlights opportunities for growth in his response to ... Marlin Equity is seeking a buyer for eMDs. Penna,s ... 22-year-old healthcare solutions Value Added Reseller and national leader ... "As the healthcare market continues to ...
Breaking Medicine Technology: