Navigation Links
Rothman at Jefferson research suggests abandon convention in diagnosing periprosthetic joint infection
Date:2/8/2012

PHILADELPHIA -- In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, while measuring a patients serum white blood cell count (WBC) and the percentage of neutrophils (PMN%), the conventional method for diagnosis, has a minimal role in the determination of PJI.

The synovial fluid is the viscous liquid that lubricates the joints and feeds the cartilage.

"This research indicates that we may need to reexamine how we diagnose PJI," said Javad Parvizi, MD, director of Research at the Rothman Institute and Professor of Orthopedics at Jefferson Medical College.

The study retrospectively examined 2,067 cases of revision hip or knee arthroplasty between 2004 and 2010. Of these, 961 cases had a diagnosis of PJI based on institutional criteria. Preoperative WBC counts and PMN numbers were examined at and found to be only 58.8 percent sensitive for infection and 62.2 percent specific for WBC; and 57 percent sensitive and 71 percent specific at the determined threshold of 7,650 cells/ml.

The results will be shared at the American Academy of Orthopedic Surgeons (AAOS) annual meeting on Wednesday, February 8th at 11:24 am Pacific Time.

Our study confirms the long held belief that serum white blood cell count and differential has minimal role in routine work-up of patients with suspected PJI, said Parvizi, an author on this influential study.


'/>"/>

Contact: Lee-Ann Landis
leeann.landis@jefferson.edu
215-955-2240
Thomas Jefferson University
Source:Eurekalert

Page: 1

Related medicine news :

1. Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI
2. Jefferson surgeon receives outstanding performance award from American College Of Surgeons
3. Jefferson physician named 2010 Emergency Department Director of the Year
4. Jefferson researcher receives 2010 Pancreatic Cancer Action Network-AACR Career Development Award
5. Clue to switch of bladder cancer from locally contained to invasive found by Jefferson scientists
6. Jefferson urologist awarded Lifetime Achievement Award from Endourological Society
7. CancerCare names Jefferson professor Physician of the Year
8. Jefferson study determines bone marrow stromal stem cells may aid in stroke recovery
9. Thomas Jefferson University professor elected AAAS Fellow
10. Jefferson clinical trial: Can a cholesterol drug prevent colon cancer?
11. Kimmel Cancer Center at Jefferson breast cancer symposium features latest in research, treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2017)... Lewisville, TX (PRWEB) , ... July 24, 2017 ... ... grants under the federal Substance Abuse and Mental Health Services Administration’s (SAMHSA) State ... State of California Department of Health Care Services, will facilitate the development of ...
(Date:7/24/2017)... ... 2017 , ... Peruvian Ayahuasca retreat, East West Lodge, announced ... and divided between two full-time university students enrolled in U.S. or Canadian accredited ... apply for the scholarship, students are asked to submit an essay between 750 ...
(Date:7/24/2017)... ... , ... Axiad IDS , a leading provider of trusted identities for ... to expand its solution to help government contractors more quickly and cost-effectively comply ... to address the authentication requirements within NIST SP800-171, but no matter how you ...
(Date:7/24/2017)... ... ... people are taking more steps to protect themselves from sunburn, half of all adults and ... the past year. It’s common and people have been dealing with them since the dawn ... conscientious of the risks that accompany sunburns. , The team at AloeVera.com , a ...
(Date:7/24/2017)... (PRWEB) , ... July 24, 2017 , ... ... August 13-17 in National Harbor, MD. This year's theme focuses on the new ... principal benchmarks for quality and integrity in testing and calibration will be changed. ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... , July 10, 2017  The tenth annual ... Boston, MA at the Sheraton Boston Hotel, ... unparalleled access to global decision makers and innovative biotech ... life science leaders during two impactful days. BioPharm America ... delegates with additional networking opportunities with 4,500+ life science ...
(Date:7/5/2017)... England , July 5, 2017 Wolfmet ... perfect answer as physics and manufacturing combine to progress molecular ... thyroid, existing SPECT systems are unable to accurately quantify the ... only limited information regarding the success of this radiotherapy treatment ... ...
(Date:7/5/2017)... 5, 2017   BioLife Solutions , Inc. (NASDAQ: ... marketer of proprietary clinical grade cell and tissue ... ("BioLife"), today announced that it has reached an agreement ... largest shareholder, to modify its existing credit facility effective ... modification, WAVI agreed to exchange its existing $4.25 million ...
Breaking Medicine Technology: