Navigation Links
Rothman at Jefferson research suggests abandon convention in diagnosing periprosthetic joint infection
Date:2/8/2012

PHILADELPHIA -- In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, while measuring a patients serum white blood cell count (WBC) and the percentage of neutrophils (PMN%), the conventional method for diagnosis, has a minimal role in the determination of PJI.

The synovial fluid is the viscous liquid that lubricates the joints and feeds the cartilage.

"This research indicates that we may need to reexamine how we diagnose PJI," said Javad Parvizi, MD, director of Research at the Rothman Institute and Professor of Orthopedics at Jefferson Medical College.

The study retrospectively examined 2,067 cases of revision hip or knee arthroplasty between 2004 and 2010. Of these, 961 cases had a diagnosis of PJI based on institutional criteria. Preoperative WBC counts and PMN numbers were examined at and found to be only 58.8 percent sensitive for infection and 62.2 percent specific for WBC; and 57 percent sensitive and 71 percent specific at the determined threshold of 7,650 cells/ml.

The results will be shared at the American Academy of Orthopedic Surgeons (AAOS) annual meeting on Wednesday, February 8th at 11:24 am Pacific Time.

Our study confirms the long held belief that serum white blood cell count and differential has minimal role in routine work-up of patients with suspected PJI, said Parvizi, an author on this influential study.


'/>"/>

Contact: Lee-Ann Landis
leeann.landis@jefferson.edu
215-955-2240
Thomas Jefferson University
Source:Eurekalert

Page: 1

Related medicine news :

1. Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI
2. Jefferson surgeon receives outstanding performance award from American College Of Surgeons
3. Jefferson physician named 2010 Emergency Department Director of the Year
4. Jefferson researcher receives 2010 Pancreatic Cancer Action Network-AACR Career Development Award
5. Clue to switch of bladder cancer from locally contained to invasive found by Jefferson scientists
6. Jefferson urologist awarded Lifetime Achievement Award from Endourological Society
7. CancerCare names Jefferson professor Physician of the Year
8. Jefferson study determines bone marrow stromal stem cells may aid in stroke recovery
9. Thomas Jefferson University professor elected AAAS Fellow
10. Jefferson clinical trial: Can a cholesterol drug prevent colon cancer?
11. Kimmel Cancer Center at Jefferson breast cancer symposium features latest in research, treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... Northern Kentucky - Cincinnati, Ohio (PRWEB) , ... ... ... leader in the production of miniature, folded, pharmaceutical inserts and outserts. As ... & Serialization Device. This addition will enable Flottman to individually code professional ...
(Date:12/9/2016)... , ... December 09, 2016 , ... The Justin ... Dependence, Inc. (NCADD) is recommending the film Whispering Spirits and its ... District of Columbia as an education tool in the war against teen drug abuse. ...
(Date:12/9/2016)... ... ... An inventor from Cana, Va., wanted to fulfill the need for a ... , The patent-pending SAFETY STRAP FOR AMPUTEES improves accessibility. It eliminates discrimination. It is ... in a matter of minutes, or even seconds. The SAFETY STRAP FOR AMPUTEES is ...
(Date:12/9/2016)... ... December 09, 2016 , ... The Holy ... in New York, NY, on December 3rd, to benefit Holy Name Medical Center's ... annual event, which raised over $1 million - the largest event in the ...
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... "I had ... an inventor from Winchester, Va. "I thought that if the nebulizer had a more ... rather than fearing them." , He developed the patent-pending NEBY to avoid the need ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... , Dec. 9, 2016 MSD, a ... supply chain solutions to alternate site health care facilities, ... First Choice Medical Supply ("First Choice"), a privately held ... the skilled nursing and home health segments. We would ... This compelling transaction will deliver significant ...
(Date:12/9/2016)... -- Research and Markets has announced the addition ... report to their offering. ... Market growth can be attributed ... pharmaceutical and biotechnology industry and technological advancements like automation and ... and growing research activities in toxicology and stem cells provide ...
(Date:12/9/2016)... 9, 2016 Research and Markets has announced ... report to their offering. ... The global travel vaccines market to grow at a ... covers the present scenario and the growth prospects of the global ... report considers the revenue generated from the sales of various vaccines ...
Breaking Medicine Technology: