Navigation Links
Rooting out recurrent breast cancer
Date:2/8/2013

Due to chemotherapy resistance and a high rate of relapse, triple negative cancers are among the most difficult breast cancers to treat. In this issue of the Journal of Clinical Investigation, researchers led by Carlos Arteaga at Vanderbilt University identified a protein, TGF-β, that is highly expressed in triple negative breast cancer cells after chemotherapy. In a mouse model of breast cancer, TGF-β both diverted cells down a path to becoming cancerous and allowed for cancer to come back after treatment. Importantly, loss of TGF-β prevented tumor recurrence in mice. These studies identify a mechanism by which cancer cells elude standard chemotherapy and provide a rationale for testing the therapeutic potential of agents that block TGF-β.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Study drug is first to help patients with recurrent low-grade ovarian cancer
2. Unnecessary antimicrobial use increases risk of recurrent infectious diarrhea
3. Research shows that a prolonged fertility window can cause recurrent miscarriage
4. Common data determinants of recurrent cancer are broken, mislead researchers
5. Immune system changes may drive aggressiveness of recurrent tumors
6. Benefit of PET or PET/CT in recurrent bowel cancer is not proven
7. Mayo Clinic gets FDA approval for new imaging agent for recurrent prostate cancer
8. Daily Aspirin May Help Those at Risk for Recurrent Blood Clots
9. Study suggests new way to prevent recurrent ear infections
10. Current and former smokers at risk for recurrent hepatitis post-liver transplantation
11. Breast-Feeding Still Less Common for Black Babies: CDC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... , ... March 23, 2017 - Crawford Technologies announced today ... invoices, bills, statements and other correspondence when they have been lost or destroyed. ... print the documents and batch them for efficient handling. , Many organizations ...
(Date:3/23/2017)... ... March 23, 2017 , ... Sharon Kleyne, host of the ... and Your Health on VoiceAmerica, recently talked on her program about how she is ... occasion to remind listeners of an important distinction. World Water Day, Kleyne pointed out, ...
(Date:3/23/2017)... CA (PRWEB) , ... March 23, 2017 , ... ... FACIS Monthly Monitoring Healthcare products at competitive pricing. Verisys through ... sanctions, Exclusions, Debarments, License restrictions and Disciplinary actions. , “We are delighted to ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... and the New MEDDEV 2.7/1 Rev. 4 Guidance, **An FDAnews Webinar**, April ... , How will the new EU MDR language change the way manufacturers ...
(Date:3/23/2017)... ... ... “Wounded Woman Be Ye Healed-Passing On A Legacy”: a call to heal the wounded ... published author, Desiree M Webb, a registered nurse, minister of music, speaker, songwriter, recording ... her husband, Paul, for over twenty-nine years. Desiree enjoys writing, beach trips, ministering ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... COPENHAGEN, Denmark , March 23, 2017 ... utilizes its innovative TransCon technology to address significant unmet ... company will host a conference call and webcast on ... of the Endocrine Society in Orlando, Florida ... rare disease pipeline candidates (TransCon Growth Hormone, TransCon PTH ...
(Date:3/23/2017)... 23, 2017 Prima BioMed has ... trial of IMP321 in combination with Keytruda, with one ... cohort experiencing a complete response. Recruitment in the second ... to be fully recruited by Q317. Preliminary efficacy data ... cancer study are expected mid-year (recruitment in the 226-patient ...
(Date:3/23/2017)... 2017 Piramal Pharma Solutions ... el nombramiento de Stuart E. Needleman ... servicios integrados completa para su base de clientes ... en el crecimiento y ejecución de las ofertas ... impulsar todas las actividades de desarrollo empresarial global ...
Breaking Medicine Technology: