Navigation Links
Role of alcohol intake and smoking on upper aerodigestive cancers
Date:9/6/2011

This paper provides an extensive analysis of the proportion of the risk of upper aero-digestive tract (UADT) cancers in the population (the population attributable risk) that may be due to alcohol consumption and/or smoking. The analyse provides strong evidence that smoking is the most important factor in the risk of these cancers, and the risk is enhanced among those who smoke and also consume 2 or more drinks per day. Alcohol alone (i.e., among non-smokers) has little effect on the risk (less than 1%).

The authors state that their observations "are consistent with the hypothesis that alcohol acts as a carcinogen primarily because of its promoting effect on tobacco smoke." In terms of the population-attributable risk, the authors conclude that "Our findings confirm that tobacco and alcohol together explain 73% of total UADT cancer burden in Europe." Overall, tobacco use alone explained 28.7%, the combination of smoking and drinking 43.9%, and alcohol use alone only 0.4% of the population attributable risk. However, among women, the risk of these cancers was higher among smokers than among those who both smoked and consumed alcohol.

Comments on the present paper: This was a case-control analysis, which is usual for uncommon types of cancer. Controls were matched on age, gender, and area of residence, but some of the analyses also adjusted for educational level. Forum members thought it unusual that the investigators considered as "ever drinkers" only subjects reporting 2 or more drinks per day; in most countries, the majority of light-to-moderate drinkers would be classified as never drinkers by this definition. The data presented do not permit an evaluation of effects for lower levels of alcohol intake. However, given that even at 2 or more drinks per day the effects of alcohol alone on population attributable risk were very small, it could be assumed that lighter drinking may have even less of a direct effect on the risk of
'/>"/>

Contact: R Curtis Ellison
ellison@bu.edu
508-333-1256
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Alcohol dulls brain alarm that monitors mistakes, MU study finds
2. Study: Community organization can reduce, negate impact of alcohol outlets on neighborhood violence
3. Does moderate alcohol consumption increase body weight?
4. More Evidence That Alcohol Hinders Good Sleep
5. Alcohol consumption in relation to acute pancreatitis
6. The effects of smoking and alcohol use on risk of upper aero-digestive cancers
7. NIH awards WSU researcher $1.7 million to study non-alcoholic fatty liver disease
8. Returning vets alcohol abuse addressed in virtual reality study
9. Drinking Alcohol May Prolong, Not Relieve, Stress
10. Alcohol Affects Left, Right Heart Chambers Differently
11. Overall health effects of alcohol consumption
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... tract has long been considered to be between 180 ... have used refined microscopic techniques that indicate a much ... gastro-intestinal tract is only as large as a normal ... tract, which passes from the mouth through the esophagus ... about 5 meters in a normal adult, and is ...
(Date:4/23/2014)... doctors predict which patients might suffer potentially fatal side-effects ... which assesses brain scans using pattern recognition software similar ... has been developed by researchers at Imperial College London. ... Trust, which used the software are published in the ... over 15 million people each year worldwide. Ischemic strokes ...
(Date:4/23/2014)... American Gastroenterological Association (AGA) Research Foundation is pleased ... AGA Research Scholar Awards program, launched in 1984, ... research careers in digestive diseases. This year, the ... allowing for three consecutive years of funding. , ... are paving the way for promising research developments ...
(Date:4/23/2014)... often displayed in the popular Swedish children,s TV ... high-sugar foods. A new study from the University ... children,s TV programmes as well as the link ... weight status. , Steingerdur Olafsdottir,s doctoral thesis focuses ... Swedish children,s TV show Bolibompa. Healthy foods dominated ...
(Date:4/23/2014)... 21, 2014 Five for-profit and non-profit organizations ... million in Proof of Concept grants to accelerate ... commercial products, the Life Sciences Discovery Fund (LSDF) ... Mentoring Program grant to the Washington Biotechnology & ... network to train the next generation of entrepreneurs ...
Breaking Medicine News(10 mins):Health News:The surface area of the digestive tract 'only' as large as a studio apartment 2Health News:Airport security-style technology could help doctors decide on stroke treatment 2Health News:Airport security-style technology could help doctors decide on stroke treatment 3Health News:AGA announces 2014 Class of AGA Research Scholars 2Health News:High-calorie and low-nutrient foods in kids' TV 2Health News:LSDF announces commercialization grants and Entrepreneur Mentoring Program 2
... (Nasdaq: ONXX ) today announced that it ... Conference on Thursday,May 1, at 8:00 a.m. Eastern ... of the presentation on our website at:, ... listeners log on 15 minutes early in order ...
... Mich., April 24 The Perrigo Company,(Nasdaq: PRGO ... from the,U.S. Food and Drug Administration (FDA) to market ... 4 mg (base) (Orange, Coated)., The FDA has ... drug, GlaxoSmithKline,s Nicorette(R) Gum, 2 mg (base) and 4 ...
... Courage Center is hosting a,credentialed educational forum on ... Golden Valley Road. The session offers three CEUs, ... Worker." Registration is from,8-8:30am with the session itself ... Golden Valley., Session participants will gain a ...
... LOUISVILLE, Ky., April 24 Ventas, Inc. (NYSE:,VTR) ... its May,19, 2008 annual meeting of shareholders, the Company,s ... $10 billion NYSE-listed real estate investment trust with assets,in ... Chicago as our,headquarters will provide the Company with increased ...
... difference after 65, study finds , , THURSDAY, April 24 (HealthDay News) ... money, appears to apply to the risk of stroke, a new ... stroke between the ages of 50 and 64, according to the ... Michigan Health and Retirement Study. , And the most probable reason ...
... WEST CHESTER, Ohio, April 24 Employees at ... a voluntary program,designed to promote healthy lifestyles. Modeled after ... salaried employees began a,12-week weight-loss contest in January -- ... a combined 4,256 pounds -- more than two tons ...
Cached Medicine News:Health News:Perrigo Receives FDA Approval to Market Orange, Coated Nicotine Gum 2Health News:Ventas Names Chicago as Headquarters 2Health News:Ventas Names Chicago as Headquarters 3Health News:Ventas Names Chicago as Headquarters 4Health News:Ventas Names Chicago as Headquarters 5Health News:Higher Wealth Linked to Lower Risk of Early Stroke 2Health News:Higher Wealth Linked to Lower Risk of Early Stroke 3Health News:AK Steel Employees Compete for the Health of It 2
(Date:1/15/2014)... , Jan. 15, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements ... announced tender offer by its indirect wholly-owned subsidiary, Sapphire ... of common stock of Solta Medical, Inc. (NASDAQ: ...
(Date:1/15/2014)... Ohio , Jan. 15, 2014  A novel wearable injector ... easy and painless for patients to self-inject prescription drugs in ... disorders, including cancer, blood diseases, autoimmune deficiencies, and genetic disorders.  ... to grow to $220B by 2018, according to analysts.   Many ...
(Date:1/14/2014)... The Brandeis Medical Center, led by Dr. Emmanuel Brandeis , ... laser tattoo removal experience with the advanced Astanza Duality laser and ... quality cosmetic services with cutting edge medical technology and offering expert ... has seen a dramatic increase in the presence of ...
Breaking Medicine Technology:Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... 4, 2012 /PRNewswire-iReach/ -- MediGain, a ... analytics, today announced the release of OptimOncology, a ... financial costing for office-based oncology practices.  This unique ... and provides measurable results for oncology practices. ...
... 2012 /PRNewswire-iReach/ -- Semantelli Corporation announced ... chosen Semantelli,s CoProtect® to manage its online ... life sciences industries, first compliance ready, actionable ... http://photos.prnewswire.com/prnh/20120104/CG30171 ) Semantelli,s compliance ready, ...
Cached Medicine Technology:MediGain Announces Release of New Oncology Analytics Solution 2Global Pharma Selects Semantelli's Compliance Ready Social Listening Platform to Manage Corporate Reputation 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: