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Role of Screening, Monitoring in Early Kidney Disease Unclear
Date:4/17/2012

provide the same benefits as ACE inhibitors and ARBs. Statins (cholesterol-lowering drugs) and beta blockers (drugs that help regulate heart rate and lower blood pressure) showed a reduction in the risk of death and cardiovascular events compared to placebo, but only in people with worsening kidney disease, or high cholesterol or congestive heart failure.

"This review shows that the evidence in early chronic kidney disease is very, very weak. The problem right now is that no one knows who will get worse and progress to end-stage renal disease," said Dr. Robert Provenzano, chair of the department of nephrology at St. John Providence Health System in Detroit, Mich.

Provenzano added that he wasn't surprised the reviewers found ACE inhibitors and ARBs to be most effective for people with early kidney disease.

He said that if people are interested in keeping their kidneys healthy, they should follow the same advice for keeping your heart healthy. Eat right to control your blood sugar, cholesterol and blood pressure levels. Limit the salt in your diet. Don't smoke, and stay active.

More information

Learn more about chronic kidney disease from the National Kidney Foundation.

SOURCES: Howard Fink, M.D., M.P.H., staff physician, Veterans Affairs Medical Center, Minneapolis, Minn.; Robert Provenzano, M.D., chair, department of nephrology, St. John Providence Health System, Detroit, Mich.; April 17, 2012, Annals of Internal Medicine


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