Navigation Links
Rochester study raises new questions about controversial plastics chemical
Date:1/27/2009

A University of Rochester Medical Center study challenges common assumptions about the chemical bisphenol A (BPA), by showing that in some people, surprisingly high levels remain in the body even after fasting for as long as 24 hours. The finding suggests that BPA exposure may come from non-food sources, or that BPA is not rapidly metabolized, or both.

The journal Environmental Health Perspectives published the research online January 28, 2009.

Controversy around BPA is mounting. In December the U.S. Food and Drug Administration agreed to reconsider the health risks of the chemical, which is used to make plastic baby bottles, water bottles and many other consumer products. Scientific studies suggest that BPA may harm the brain and prostate glands in developing fetuses and infants; adults with higher BPA levels in their urine were linked to higher risks for heart disease and diabetes, according to a study published last September in the Journal of the American Medical Association.

The latest finding from Rochester is important because, until now, scientists believed that BPA was excreted quickly and that people were exposed to BPA primarily through food. Indeed, the FDA and the European Food Safety Authority have declared BPA safe based, in part, on those assumptions.

"Our results simply do not fit that picture," said lead author Richard W. Stahlhut, M.D., M.P.H., of the University of Rochester's Environmental Health Sciences Center. "The research community has clues that could help explain some of these results but to date the importance of the clues have been underestimated. We must chase them much more vigorously now."

Manufacturers use BPA to harden plastics in many types of products. In addition to plastic bottles, BPA is used in PVC water pipes and food storage containers. BPA also coats the inside of metal food cans, and is used in dental sealants.

Stahlhut and colleagues obtained data for a sample of 1,469 American adults through the Center for Disease Control's National Health and Nutrition Examination Survey (NHANES). The researchers sought to explore the link between BPA urine concentration and the length of time a person had been fasting.

Accepting the widely held assumption that food is the most common route of exposure to BPA, Stahlhut expected to see a relationship between the last food ingested, fasting time, and BPA levels. People who had fasted longest (15 to 24 hours), for example, should have had much lower BPA levels than people who had eaten more recently, Stahlhut said.

Instead, those who fasted had levels that were only moderately lower than people who had just eaten. This is significant because scientists expected BPA levels to decrease by about half, every five hours.

"In our data, BPA levels appear to drop about eight times more slowly than expected so slowly, in fact, that race and sex together have as big an influence on BPA levels as fasting time," Stahlhut said.

According to the authors, two possible explanations may exist for the higher-than-expected levels of BPA in people who fasted. One is that exposure to BPA might come through other means, such as house dust or tap water.

In addition, Stahlhut theorizes that BPA may seep into fat tissues, where it would be released more slowly. However, further study is needed to evaluate the effects of BPA on adipose tissue hormones and function, Stahlhut said, as well as more studies to compare BPA levels in fat versus blood and urine.

The Centers for Disease Control estimates that 93 percent of Americans have detectable levels of BPA in their urine.

The latest data also supports the idea that individuals might be re-exposed throughout the course of a day, Stahlhut said. In 2000 another research group found that BPA can migrate from PVC pipes or hoses into room temperature water, producing another potential route of exposure.


'/>"/>

Contact: Leslie Orr
Leslie_orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Related medicine news :

1. Rochester Medical Announces First Quarter 2009 Earnings Conference Call February 2, 2009
2. Rochester Medical Announces Settlement With TYCO Healthcare Group, L.P., Now Operating as Covidien Ltd.
3. Rochester Shoulder Surgeon Blends Innovative Techniques with Personalized Patient Care
4. Rochester Medical Reports Record Fourth Quarter Sales and Record Annual Sales
5. Rochester Medical Announces Fourth Quarter 2008 Earnings Conference Call November 6, 2008
6. Balloon Manor Reappears in Rochester
7. Safety Threat to Rochester Still Remains Despite Approval Of Canadian Pacifics Railroad Acquisition Of DM&E
8. Rochester Medical Implants Achieves ISO 13485:2003 Certification for Medical Device Manufacturing
9. Autovan Donates Wheelchair-Accessible Van; Brings Greater Mobility to Facility in Rochester, New York
10. Rochester Medical Honored by Premier Healthcare Alliance for Exceeding Performance Expectations
11. Rochester Coalition and Mayo Clinic Challenge Railroads Contention That Hazmat Rail Shipments Pose no Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American Institutes ... Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , ... advance care planning, healthcare costs and patient and family engagement. , AIR researchers ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... care operating models within the health care industry is ... financial efficiency , Deloitte offers a suite of ... business issues impacting efficient cost optimization: labor resource analysis, ... These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
Breaking Medicine Technology: