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Rochester study raises new questions about controversial plastics chemical
Date:1/27/2009

A University of Rochester Medical Center study challenges common assumptions about the chemical bisphenol A (BPA), by showing that in some people, surprisingly high levels remain in the body even after fasting for as long as 24 hours. The finding suggests that BPA exposure may come from non-food sources, or that BPA is not rapidly metabolized, or both.

The journal Environmental Health Perspectives published the research online January 28, 2009.

Controversy around BPA is mounting. In December the U.S. Food and Drug Administration agreed to reconsider the health risks of the chemical, which is used to make plastic baby bottles, water bottles and many other consumer products. Scientific studies suggest that BPA may harm the brain and prostate glands in developing fetuses and infants; adults with higher BPA levels in their urine were linked to higher risks for heart disease and diabetes, according to a study published last September in the Journal of the American Medical Association.

The latest finding from Rochester is important because, until now, scientists believed that BPA was excreted quickly and that people were exposed to BPA primarily through food. Indeed, the FDA and the European Food Safety Authority have declared BPA safe based, in part, on those assumptions.

"Our results simply do not fit that picture," said lead author Richard W. Stahlhut, M.D., M.P.H., of the University of Rochester's Environmental Health Sciences Center. "The research community has clues that could help explain some of these results but to date the importance of the clues have been underestimated. We must chase them much more vigorously now."

Manufacturers use BPA to harden plastics in many types of products. In addition to plastic bottles, BPA is used in PVC water pipes and food storage containers. BPA also coats the inside of metal food cans, and is used in dental sealants.

Stahlhut and colleagues obtained dat
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Contact: Leslie Orr
Leslie_orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

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