Navigation Links
Roche to Commence Phase III Trials with Innovative Treatment Designed to Lower Cardiovascular Risk in Diabetes Patients with Recent Heart Attack
Date:6/9/2009

- SYNCHRONY Study Published in The Lancet Supports Cardio-Protective Potential of Aleglitazar -

NUTLEY, N.J., June 9 /PRNewswire/ -- Roche today announced it will start Phase III clinical investigations for aleglitazar, its innovative PPAR co-agonist R1439 which is uniquely designed to reduce cardiovascular morbidity and mortality in high risk patients with type 2 diabetes. This decision is supported by data from the Phase II SYNCHRONY study published today in The Lancet(1) and announced at the American Diabetes Association meeting in New Orleans. The Phase III program is anticipated to start in the second half of 2009.

SYNCHRONY, a placebo-controlled dose ranging study in type 2 diabetes patients, showed that aleglitazar had a balanced synergistic effect on both lipid and glucose control with a good safety and tolerability profile in patients with type 2 diabetes.

Cardiovascular disease is currently the leading cause of death among those with type 2 diabetes, accounting for half of all deaths.(2) Despite guidelines recommending that cardiovascular risk in this patient group should be reduced by controlling factors such as dyslipidemia, blood pressure, body weight and hyperglycemia,(3,4) the majority of patients still do not achieve their treatment goals leaving them vulnerable to both initial and residual cardiovascular events.(3,5) Significantly, one in ten patients with an acute myocardial infarction died within a year.(6)

"Roche is confident that aleglitazar has the potential to reduce cardiovascular morbidity and mortality in this high-risk patient group and is therefore committed to pursuing its rapid development," said Jean-Jacques Garaud, Global Head of Development Pharmaceuticals Division of Roche.

The focused Phase III outcomes trial will investigate whether once daily 150 micrograms aleglitazar reduces the incidence of cardiovascular mortality, non-f
'/>"/>

SOURCE Roche
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Raptor Pharmaceuticals to Collaborate with Roche on Therapeutic Delivery Across Blood-Brain Barrier
2. moksha8 Expands Alliance With Roche to Commercialize $200 Million of Products in Brazil and Mexico
3. Roches Pierson Honored as 2009 HBA Rising Star
4. Corporate Pandemic Preparedness Experts from Roche & PSEG to Advise Savvy Business Leaders May 15
5. Roche Women Honored as 2009 TWIN Awardees
6. Rochester Medical Reports Second Quarter Results
7. Sanofi-Aventis and Roche/Chugais Drugs Will Dominate the Indian Colorectal Cancer Drug Market Through 2013
8. Roche Announces New Co-pay Program in Pennsylvania that Makes It Easier for Patients with Diabetes to Receive Savings on ACCU-CHEK(R) Blood Glucose Test Strips
9. Roche Announces New Co-pay Program in Florida that Makes It Easier for Patients with Diabetes to Receive Savings on ACCU-CHEK(R) Blood Glucose Test Strips
10. Roche Announces New Co-Pay Program in California That Makes it Easier for Patients With Diabetes to Receive Savings on ACCU-CHEK(R) Blood Glucose Test Strips
11. Rochester Medical Announces Second Quarter 2009 Earnings Conference Call April 30, 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... ... August 27, 2015 , ... Healthpointe is proud to ... Tijera Clinic in Los Angeles. Licensed to practice Chinese Needle Therapy since 1983, Dr. ... injuries and diseases. Dr. Priebe also practices in Healthpointe’s La Mirada clinic and Garden ...
(Date:8/27/2015)... ... August 27, 2015 , ... More destinations and stores are becoming ... why Amica Insurance is sharing some tips to help your whole family travel safely ... people travel with pets each year. Amica is sharing the following tips from the ...
(Date:8/27/2015)... JOHNSON CITY, Tenn. (PRWEB) , ... August 27, 2015 , ... ... Technology LLC, DBA All Clear System. The agreement will enable both Johnson City, Tenn.-based ... , All Clear System is a cloud-based safety product that caters to organizations in ...
(Date:8/27/2015)... ... 27, 2015 , ... For the first time, Ninja® introduces ... Nutri Ninja® Auto-iQ Pro Complete and Nutri Ninja Auto-iQ Compact System. These two ... customization to a whole new level. This line of Nutri Ninja products is ...
(Date:8/27/2015)... ... ... Pinellas, located at 1395 South Pinellas Avenue in Tarpon Springs, will open a free-standing emergency ... at US Highway 19 North and Highlands Boulevard, less than eight miles from the main ... is slated to begin in September 2015. , The new 24-bed facility will ...
Breaking Medicine News(10 mins):Health News:Qualified Medical Examiner and Acupuncturist Joins Healthpointe in Los Angeles 2Health News:Qualified Medical Examiner and Acupuncturist Joins Healthpointe in Los Angeles 3Health News:Amica Unleashes 5 Tips for Safe Traveling with Pets 2Health News:Banc Intranets Forms Strategic Marketing Partnership with All Clear System 2Health News:Banc Intranets Forms Strategic Marketing Partnership with All Clear System 3Health News:Banc Intranets Forms Strategic Marketing Partnership with All Clear System 4Health News:SharkNinja's Nutri Ninja® Auto-iQ™ Pro Complete Delivers Power And Versatility In A Compact Design 2Health News:SharkNinja's Nutri Ninja® Auto-iQ™ Pro Complete Delivers Power And Versatility In A Compact Design 3Health News:SharkNinja's Nutri Ninja® Auto-iQ™ Pro Complete Delivers Power And Versatility In A Compact Design 4Health News:Florida Hospital North Pinellas is Opening a New Free-Standing Emergency Room in Palm Harbor 2Health News:Florida Hospital North Pinellas is Opening a New Free-Standing Emergency Room in Palm Harbor 3
... Alcohol consumption causes alteration in several cellular mechanisms, ... fibrosis. These phenomena are associated to significant changes ... liver cell memory. Although inhibition of proteasome function ... liver disease (ALD), why proteasome dysfunction may enhance ...
... peptic ulcer seems to be increasing in Japan in ... whom metabolic syndrome frequently develops. However, a therapeutic and ... been established. , A research team led by Dr. ... will be published on February 14, 2009 in the ...
... Swedes are under treatment with the blood-thinning drug Waran. ... the initiation of treatment a risky balancing act between ... University have developed a model for calculating the appropriate ... the scientific publication New England Journal of Medicine ...
... 19 Executives at Sage, an industry-,leading ... interoperable electronic,health records (EHR - http://tinyurl.com/ah9dgb ... providers and federally qualified,health centers, today joined ... in applauding the signing of the American,Reinvestment ...
... Given the growing strain placed on the power grid ... and storage, corporations have no choice but to ... However, according to a Siemens survey released today, many ... efficiency expectations. The new study, which examined general ...
... Loss Partners Begin Nationwide Mobile Bus Tour to Promote ... in MusicPARSIPPANY, N.J., Feb. 19 Today alli and ... mobile bus tour, further promoting the brand,s commitment to ... in Los Angeles, the mobile bus will embark on ...
Cached Medicine News:Health News:Proteasome inhibition affects epigenetic mechanisms 2Health News:What is the most effective therapy for low-dose aspirin induced peptic ulcer? 2Health News:Knowledge of genetics improves uncertain medication 2Health News:Electronic Health Records (EHR) 'Leap Forward' Thanks to American Reinvestment and Recovery Act 2Health News:Electronic Health Records (EHR) 'Leap Forward' Thanks to American Reinvestment and Recovery Act 3Health News:Siemens Survey Reveals Low Awareness of Escalating Need for Superior Data Center Efficiency 2Health News:Siemens Survey Reveals Low Awareness of Escalating Need for Superior Data Center Efficiency 3Health News:Wynonna Judd and alli(R) Hit The Road for a Healthier America 2Health News:Wynonna Judd and alli(R) Hit The Road for a Healthier America 3Health News:Wynonna Judd and alli(R) Hit The Road for a Healthier America 4Health News:Wynonna Judd and alli(R) Hit The Road for a Healthier America 5
(Date:8/27/2015)... 2015 The Elekta Linac-based Brain ... Boston on July 9th for its inaugural ... more fully exploit the potential of advances in linear ... "As an established provider of sophisticated cancer ... a leadership role - in collaboration with its clinical ...
(Date:8/27/2015)... 27, 2015 According to ... Research titled "Global Market Study on Urinary Catheters: ... 2021", the urinary catheters market is expected to be valued ... It is anticipated to expand at a CAGR ... Mn by 2021. View full report TOC ...
(Date:8/27/2015)... and SOUTH SAN FRANCISCO, ... Pulmonary Fibrosis Foundation (PFF) and ... that the organizations are partnering on a U.S. ... experiences with interstitial lung diseases (ILDs), including idiopathic ... Journey (INTENSITY) survey will assess the steps and ...
Breaking Medicine Technology:New Elekta Consortium to Push Frontiers of Linear Accelerator-Based Stereotactic Radiation Therapy for the Brain 2New Elekta Consortium to Push Frontiers of Linear Accelerator-Based Stereotactic Radiation Therapy for the Brain 3Global Urinary Catheters Market Will Reach US$1,755.0 Mn by 2021: Persistence Market Research 2Global Urinary Catheters Market Will Reach US$1,755.0 Mn by 2021: Persistence Market Research 3Global Urinary Catheters Market Will Reach US$1,755.0 Mn by 2021: Persistence Market Research 4Pulmonary Fibrosis Foundation and Veracyte Partner on Survey Exploring Diagnostic Experiences of U.S. Patients with Interstitial Lung Disease 2Pulmonary Fibrosis Foundation and Veracyte Partner on Survey Exploring Diagnostic Experiences of U.S. Patients with Interstitial Lung Disease 3Pulmonary Fibrosis Foundation and Veracyte Partner on Survey Exploring Diagnostic Experiences of U.S. Patients with Interstitial Lung Disease 4
... OAK BROOK, Ill. , July 12 The University ... agreement to Ascent, a leader in health care resource sustainability. The agreement, ... 1, 2010 . Under the contract, Ascent will offer single-use device (SUD) ... , , , ...
... July 12 ( http://www.myprgenie.com ) -- Medrium, Inc., one ... announced it has signed a partnership agreement with RelayHealth to use ... LabCorp and to provide LabCorp results to physicians utilizing the Medrium ... , ...
Cached Medicine Technology:University HealthSystem Consortium Awards Single-Source Agreement to Ascent for Medical Device Reprocessing Services 2University HealthSystem Consortium Awards Single-Source Agreement to Ascent for Medical Device Reprocessing Services 3Medrium Partners With RelayHealth 2Medrium Partners With RelayHealth 3
Cold light source single outlet....
Cold light source single outlet....
Cold light source single outlet....
Cold light source triple outlet....
Medicine Products: