Navigation Links
Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C
Date:8/19/2009

treatment for a total of 48 weeks.

About RG7227/ ITMN-191

RG7227/ ITMN-191 is a potent, macrocyclic inhibitor of HCV NS3/4A protease activity, and has produced multi-log10 reductions in HCV levels in chronic HCV patients, when administered for 14 days as monotherapy. When RG7227/ ITMN-191 is combined with PEGASYS and COPEGUS, or the NS5B polymerase inhibitor RG7128, it reduced viral loads below the limit of detection in a majority of study-treated patients. RG7227/ ITMN-191 was safe and well tolerated in these studies.

About PEGASYS

PEGASYS, in combination with COPEGUS (ribavirin), is indicated for the treatment of adults with chronic HCV who have compensated liver disease and have not previously been treated with interferon alpha. Efficacy has been demonstrated in patients with compensated liver disease and histological evidence of cirrhosis (Child-Pugh class A) and patients with HIV disease that are clinically stable (e.g., antiretroviral therapy not required or receiving stable antiretroviral therapy). In addition, PEGASYS in combination with COPEGUS is the first and only FDA-approved regimen for the treatment of chronic HCV in patients coinfected with HCV and HIV. PEGASYS is the only pegylated interferon indicated for the treatment of adult patients with chronic hepatitis B (HBeAg positive and HBeAg negative chronic hepatitis B who have compensated liver disease and evidence of viral replication and liver inflammation).

PEGASYS is dosed at 180mcg as a subcutaneous injection taken once a week. COPEGUS is available as a 200mg tablet, and is administered orally two times a day as a split dose. Roche has backed PEGASYS with the most extensive clinical research program ever undertaken in HCV, with major studies initiated to advance treatment for HCV patients with unmet needs, including patients co-infected with HIV and HCV, African Americans, patients with cirrhosis, and p
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Rochester Medical Reports Third Quarter Results
2. Roche Cardiac 200 Offers Rapid Cardiac Diagnostics for the Point of Care
3. Rochester Medical Announces Third Quarter 2009 Earnings Conference Call July 30, 2009
4. Enigma Diagnostics Announces Signing of Patent Licenses With Roche Molecular Systems, Inc.
5. Roche Diabetes Care Announces Unique Coaching Program for Diabetes Educators as Part of Long-Term Commitment to Fight the Disease
6. NJLRA Statement in Response to Roches Discontinuation of Accutane(R)
7. Orochem Technologies Acquires Oligonet, a Custom Oligo Synthesis Business
8. Purple Communications Dream Bigger Initiative Honors Rochester Physician and Deaf Community Trailblazer
9. Rochester Medical Corporation Set to Join Russell 3000 Index
10. Roche to Commence Phase III Trials with Innovative Treatment Designed to Lower Cardiovascular Risk in Diabetes Patients with Recent Heart Attack
11. Raptor Pharmaceuticals to Collaborate with Roche on Therapeutic Delivery Across Blood-Brain Barrier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , ... July 31, 2015 , ... “ Crack’em ” ... latest and coolest technology products available to consumers. Amanda Forstrom, a technology expert and ... helps chefs make less mess while cooking. , Cooking can be a very messy ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... Super-Sod wants ... with a Super-Sod Pro Page as the perfect fit for such a ... pictures and articles. The social website is a dynamic site that spreads home and ...
(Date:7/31/2015)... , ... July 31, 2015 , ... In the most ... U.S. District Court in the Northern District of Illinois, Androgel testosterone attorneys report that ... 20, a docket entry was made recording the minutes of the status conference, which ...
(Date:7/31/2015)... ... July 31, 2015 , ... Nutritional Products ... of nutritional and wellness products, announced the addition of Vincent Aquilino to its ... active isolated stretching and the prevention and rehabilitation of injuries, has spent the ...
(Date:7/31/2015)... ... , ... Easter Seals Southern Georgia’s Heels & Wheels Duathlon & Triathlon will be held Saturday, ... AM. The duathlon is a 2 mile run, 13 mile bike ride, and a 3 ... mile bike, and a 3 mile run. Heels & Wheels is sponsored by Mayo ...
Breaking Medicine News(10 mins):Health News:Make Less Mess while Cooking with Crack’em 2Health News:Super-Sod Created a Landscape Profile on Houzz.com for Home Garden Design 2Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 2Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 3Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 4Health News:NPI Welcomes Vincent Aquilino to Board of Directors 2Health News:Heels & Wheels for Megan's House Set for Saturday August 22, 2015 in Waycross, Georgia 2
... , MONDAY, Dec. 5 (HealthDay News) -- When people with ... a third worrisome condition -- dementia -- goes up ... 2 diabetes are twice as likely to develop dementia three ... nondepressed people with diabetes, researchers found. "We,ve known for ...
... Calif. -- Aspirin taken within five days of cardiac ... risk of major postoperative complications, including renal failure, a ... (30-day mortality), according to a study by researchers at ... to appear in the journal Annals of Surgery ...
... been launched to help raise awareness of work being done ... childhood obesity and to seek the views of parents and ... of childhood overweight and obesity, led by a team of ... One-quarter of babies gain weight more rapidly than they should ...
... HealthDay Reporter , MONDAY, Dec. 5 (HealthDay News) -- ... using a preventive medication, according to new research. That ... the late 1980s. Preventive asthma medications help control ... the U.S. National Asthma Education and Prevention Program recommend their ...
... available in German . , The extent ... depends on motivation and will power or the physical condition ... latter particularly leads to noticeable and measurable performance impairments. For ... confined to changes in the muscle itself. Now, a joint ...
... 4 (HealthDay News) -- Variations in genes involved in ... disorder (ADHD), according to a new study. The ... may offer a new treatment option for ADHD patients ... researchers said. In the study, researchers conducted whole-genome ...
Cached Medicine News:Health News:Risk for Dementia Rises When Diabetes, Depression Meet: Study 2Health News:Risk for Dementia Rises When Diabetes, Depression Meet: Study 3Health News:Preoperative aspirin therapy can benefit cardiac surgery patients 2Health News:Parents' views sought on childhood obesity risk 2Health News:More Children Using Preventive Asthma Drugs: Study 2Health News:More Children Using Preventive Asthma Drugs: Study 3Health News:How muscle fatigue originates in the head 2Health News:More Evidence Links Specific Genes to ADHD 2
(Date:7/30/2015)... 2015 Edwards Lifesciences Corporation (NYSE: EW ), ... hemodynamic monitoring, today announced that Robert A. Ingram ... "Bob is an ardent champion for innovation in the lifesciences ... him on Edwards, board as we pursue our focused innovation ... CEO.  "Bob has provided a valuable perspective to our board, ...
(Date:7/30/2015)... -- Mettler-Toledo International Inc. (NYSE: MTD ) today ... the highlights: , Sales in local currency ... year. Reported sales decreased 4% as currency reduced sales ... earnings per diluted share as reported (EPS) were $2.73, ... was $2.80 , an increase of 9% over ...
(Date:7/30/2015)... , July 30, 2015  ResMed (NYSE: ... signed a definitive agreement to acquire Curative ... ventilation and sleep-disordered breathing medical devices and ... market reputation in China, combined with ResMed,s global leadership in sleep and ... China suffering from ...
Breaking Medicine Technology:Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 2Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 3Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 4Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 5Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 6Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 7Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 8Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 9Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 10Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 11Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 12Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 13Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 14ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... 4, 2010 Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN ... in Phoenix, Arizona on Thursday, November 11, 2010 at 5:30 ... Bradbury, president and chief executive officer of Amylin Pharmaceuticals, will ... webcast live through the "Investors" section of Amylin,s corporate website ...
... N.C., Nov. 4, 2010 Gentris Corporation ( ... pharmacogenomics, announced today that Howard McLeod, Pharm.D., from ... (UNC) has become the Company,s first Chief Scientific ... pharmacogenomics and personalized medicine, is the Fred N. ...
Cached Medicine Technology:Gentris Corporation Names New Chief Scientific Advisor 2Gentris Corporation Names New Chief Scientific Advisor 3
... enhances productivity in the laboratory with its ... methods clotting, chromogenic and immunological ... test results every time. With user ... random access, the CA-1500 will provide you ...
... Premier is our top-of-the-line device. ... attributes of the Qwik-Let® Elite, ... Lan-X feature. The Lan-X technology ... protection in the removal and ...
... the pain and hassle of testing. Unlike ... device is the only one with a ... testing, with less hassle and improved safety. ... and no side-to-side motion for less skin ...
... The new Finnpipette Focus from Thermo Labsystems ... uncompromising performance. Advanced features such as ... fine volume adjustment on microvolumes help to ... single channel pipettes. The new interchangeable handle ...
Medicine Products: