Navigation Links
Roche and InterMune Initiate Phase 2b Clinical Trial of RG7227/ ITMN-191 in Patients With Chronic Hepatitis C
Date:8/19/2009

improved RG7227/ ITMN-191 AUC and plasma concentrations at later times. There were no remarkable safety findings.

The Phase 1 study will evaluate the safety, tolerability, pharmacokinetics and antiviral activity of once-daily and twice-daily ritonavir-boosted RG7227/ ITMN-191 regimens administered with PEGASYS and ribavirin for 14 days.

Dr. Duff commented, "Combining RG7227/ ITMN-191 with low dose ritonavir has the potential to deliver additional benefits to patients, including the requirement for less frequent dosing and fewer tablets per day. Data generated from this Phase 1 trial may pave the way for larger studies investigating this treatment combination."

RG7227/ ITMN-191 is also being investigated in combination with the NS5B polymerase inhibitor RG7128 in the INFORM-1 study. This innovative study has recently been expanded to examine regimens in which both RG7227/ ITMN-191 and RG7128 are dosed twice daily in treatment-experienced patients. Results from all cohorts of this study will be presented in an oral presentation in Presidential Plenary Session III on the morning of November 3 at the 2009 AASLD meeting. Additional abstracts regarding pharmacokinetic/pharmacodynamics and resistance have been accepted for poster presentation.

Notes to Editors

* Patients who achieve RVR, defined as undetectable viral levels (less than 15 IU/mL) by the end of week 4, will stop all treatment at week 24 and will be followed post treatment to evaluate whether they achieve SVR. Patients in the treatment arms who do not achieve RVR will continue with PEGASYS and COPEGUS treatment for a total duration of 48 weeks.

** As in Part 1, patients who achieve RVR by the end of week 4 will stop all treatment at week 24 and will be followed post treatment to evaluate whether they achieve SVR. Patients who do not achieve RVR will continue with PEGASYS and COPEGUS
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Rochester Medical Reports Third Quarter Results
2. Roche Cardiac 200 Offers Rapid Cardiac Diagnostics for the Point of Care
3. Rochester Medical Announces Third Quarter 2009 Earnings Conference Call July 30, 2009
4. Enigma Diagnostics Announces Signing of Patent Licenses With Roche Molecular Systems, Inc.
5. Roche Diabetes Care Announces Unique Coaching Program for Diabetes Educators as Part of Long-Term Commitment to Fight the Disease
6. NJLRA Statement in Response to Roches Discontinuation of Accutane(R)
7. Orochem Technologies Acquires Oligonet, a Custom Oligo Synthesis Business
8. Purple Communications Dream Bigger Initiative Honors Rochester Physician and Deaf Community Trailblazer
9. Rochester Medical Corporation Set to Join Russell 3000 Index
10. Roche to Commence Phase III Trials with Innovative Treatment Designed to Lower Cardiovascular Risk in Diabetes Patients with Recent Heart Attack
11. Raptor Pharmaceuticals to Collaborate with Roche on Therapeutic Delivery Across Blood-Brain Barrier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... (PRWEB) September 02, 2014 As an industry ... in an industry and predict change. Fortunately for him, that ... him to identify markets that are eager for change — ... of the hearing aid market indicated it was ripe for ... consumer,” Sapio explained. As a result, he took matters into ...
(Date:9/2/2014)... is available in Spanish . ... found, through an experiment conducted on rats, that hyperproteic diets ... use for groups with bone disease problems, such as the ... that vegetal proteinin the case of the present study, soy ... the former increased the level of calcium in bones by ...
(Date:9/2/2014)... nurses in their work care for patients who are ... shown that many nurses in training feel unprepared and ... during end-of-life care. , Scientists from the Sahlgrenska Academy ... Gothenburg, the University of Skvde and the Ersta Skndal ... caring for dying patients, their ideas about how to ...
(Date:9/2/2014)... September 02, 2014 Catalent, the ... development solutions for drugs, biologics and consumer health ... strategic partner, Eli Lilly’s growth, it is to ... at its Philadelphia Clinical Supply Center of Excellence. ... capabilities in its clinical supply facility in Schorndorf, ...
(Date:9/2/2014)... Splashtop Inc. , the worldwide ... NTT DoCoMo to deliver Splashtop Business Lite ... Lite is included in NTT DoCoMo’s “Business Plus” program. ... that empower users to remote access their corporate computers ... 18 million users worldwide. Splashtop delivers the best ...
Breaking Medicine News(10 mins):Health News:David Sapio Launches Zounds Hearing Franchise 2Health News:Study conducted on rats suggests that hyperproteic diets can be beneficial for bones 2Health News:Many nurses unprepared to meet dying patients 2Health News:Catalent Supports Eli Lilly's Growing Global Clinical Trials Needs with New Investment in Automated Packaging Solutions 2Health News:Splashtop and NTT DoCoMo Partner to Deliver “Splashtop Business Lite” Secure Remote Access Solution to Business Customers 2
... affect heart despite symptom relief, experts say , , MONDAY, ... longer than they did 40 years ago, but not if ... the Mayo Clinic. , "When you look at persons with ... benefits over the last several decades of improved survival the ...
... for colorectal cancer screening, nearly two-thirds of screening colonoscopies ... in the October issue of the journal Gastroenterology, Thomas ... University School of Medicine and a Regenstrief Institute, Inc. ... who is at risk for colorectal cancer as well ...
... cancer who arent eligible for standard treatment is under ... unfortunate reality is that kidney problems often result from ... cisplatin and gemcitabine, says Dr. Teresa A. Coleman, hematologist-oncologist ... II study at about 120 sites in North America, ...
... Va., Oct. 29 CEL-SCI Corporation,(Amex: CVM ) ... of cancer immunotherapies on its new website. The link ... home page at http://www.cel-sci.com . Geert ... minds of many represents the future of cancer therapy. ...
... - Halogen Software Inc., the leading,provider of Web-based ... Vonage has selected Halogen eAppraisal with,Multi-Rater. Vonage, a ... a Web-based system to streamline the appraisal process ... top-notch services to its,customers. Vonage will be ...
... crisis in the developing world because of lack of ... His Royal Highness The Duke of York, Patron of ... , In the foreword to a special supplement ... The Duke of York says that this situation is ...
Cached Medicine News:Health News:Rheumatoid Arthritis Death Rate Unchanged 2Health News:Rheumatoid Arthritis Death Rate Unchanged 3Health News:1 size may not fit all 2Health News:New treatment option studied for bladder cancer 2Health News:New treatment option studied for bladder cancer 3Health News:Vonage Selects Halogen Software - New Solution to Streamline Employee Performance and Talent Management Across Organization 2Health News:British Royal highlights anesthesia crisis in the developing world 2
(Date:9/2/2014)... 2, 2014  Based on its recent analysis ... Frost & Sullivan recognizes Novian Health, Inc. with ... for Technology Innovation Leadership. Novian Health has greatly ... tumors with its proprietary technology, Novilase ® ... accurate, and easy-to-control ultrasound-guided thermo ablation device that ...
(Date:9/2/2014)... DIEGO , Sept. 2, 2014 ResMed (NYSE: ... and Astral™ 150 devices in the United ... generation of portable, lightweight, and user-friendly life support ventilators. ... offer unparalleled mobility and ease of use for patients ... and other adult and childhood respiratory disorders. The U.S. ...
(Date:9/2/2014)... BEDFORD, Mass. , Sept. 2, 2014  Hologic, Inc. (NASDAQ: ... , President and Chief Executive Officer, will present at the ... City , New York on ... Interested parties are invited to listen to the live ... Hologic,s website at www.hologic.com/investors-overview . An archive of the ...
Breaking Medicine Technology:Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 2Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 3Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 4Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 5ResMed's Revolutionary Life Support Ventilation Platform -- Astral 100 and 150 Devices Now Available in the U.S. 2ResMed's Revolutionary Life Support Ventilation Platform -- Astral 100 and 150 Devices Now Available in the U.S. 3
... recognizes MedNet Solutions as the first QM Certified ... QualityMetric Incorporated announced today that MedNet Solutions, ... study management systems, is the first company to ... developed the QM Certified Scoring Partner program to ...
... Reports Significant Uptake of PlasmaBlade by U.S. Surgeons ... PEAK Surgical, Inc., a medical device company ... based on a proprietary technology, announced today several ... includes the PULSAR(R) Generator and the PEAK PlasmaBlade(TM) ...
Cached Medicine Technology:MedNet Solutions Certified to Score SF-12v2 Health Survey 2MedNet Solutions Certified to Score SF-12v2 Health Survey 3PEAK Surgical Announces Completion of First PRECISE Clinical Study, Receipt of Medical Design Excellence Award for PEAK(R) Surgery System and Achievement of Over 1,000 Surgeries Using PEAK PlasmaBlade(TM) 2PEAK Surgical Announces Completion of First PRECISE Clinical Study, Receipt of Medical Design Excellence Award for PEAK(R) Surgery System and Achievement of Over 1,000 Surgeries Using PEAK PlasmaBlade(TM) 3PEAK Surgical Announces Completion of First PRECISE Clinical Study, Receipt of Medical Design Excellence Award for PEAK(R) Surgery System and Achievement of Over 1,000 Surgeries Using PEAK PlasmaBlade(TM) 4
... magnifier is an easy to use, full ... so that the monitor (usually a ... magnifier and is not built in. This ... screen if desired in the future. Also ...
... Maxport is a powerful magnifier that helps the ... composed of a hand magnifier attached to a pair ... there is no need for a TV set. The ... magnify images on a book, a can of food, ...
... powerful, portable, hand-held digital magnifier designed for ... a computer mouse, Max connects directly to ... you to read newspapers, magazines, recipe cards ... any surface curved or straight. The optional ...
... Merlin is a superior full-color, auto-focus, ... vision user in mind, Merlin enables the ... black and white, high contrast positive or ... video magnifier, this optional feature enables the ...
Medicine Products: