Navigation Links
Robotic surgery outcomes data presented at head and neck cancer annual meeting
Date:7/26/2012

Predictors of disease severity in human papillomavirus-derived head and neck cancer, tobacco use, and the dramatic benefits of robotic surgery in people with head and neck cancer are among landmark research presented by Mount Sinai School of Medicine at the Eighth International Conference on Head and Neck Cancer. The meeting took place from July 21-25, 2012 in Toronto.

Highlights of Mount Sinai research at the American Head and Neck Society conference:

Transoral Robotic Surgery Shows Significant Promise in Hard-to-Treat Smokers with Head and Neck Cancer

In a retrospective study of 35 smokers and 22 nonsmokers who were treated with transoral robotic surgery and evaluated after 19.9 months, researchers found that progression-free survival was 91 percent and 96 percent and overall survival was 97 percent and 100 percent for the smoking and nonsmoking groups, respectively. They also found 94 percent and 96 percent of tumors removed using robotic surgery did not come back in the smoking and nonsmoking groups, respectively; and that the surgery prevented metastasis in 97 percent and 100 percent of these patients.

"Historically, tobacco users have a five-year disease-free survival rate of 50-60 percent. Early results of this study suggest a significant improvement in outcomes," said senior author Eric M. Genden, MD, Director of the Head and Neck Cancer Center.

"The prognosis for smokers who are diagnosed with head and neck cancer has historically been poor," said Chaz L. Stucken, MD, Chief Resident, Otolaryngology, Mount Sinai School of Medicine. "However, our analysis shows that robotic surgery is highly effective in treating these patients and should be considered as a primary treatment modality in this patient population."

Treatment with Robotic Surgery Offers Dramatic Benefit In Overall Survival in People with Head and Neck Cancer

Transoral robotic surgery (TORS) shows positive survival outcomes in treating head and neck cancer, according to a presentation from John R. de Almeida, MD, who conducted the research as an Otolaryngology fellow at Mount Sinai. In this retrospective analysis, Dr. de Almeida and his team evaluated 237 patients treated with TORS. Twenty-six percent received adjunctive radiotherapy and 32 percent received adjunctive chemotherapy. Two-year disease-specific survival and overall survival were 94 percent and 98 percent, respectively, and 21 patients experienced a recurrence.

Established Prognostic Factors May Not Apply to HPV-positive Tonsil Cancer

With a dramatic increase in the number of cases of head and neck cancer associated with HPV, researchers from Mount Sinai set out to determine whether the number of metastatic lymph nodes, a well-established measure of disease severity in the more typical tonsil cancer patient with a history of smoking and/or drinking, apply to HPV-positive tonsil cancer. They evaluated 1,515 patients from the pre-HPV era (1988-1997) and 5,139 patients from the HPV-predominant era (1998-2007), all from the Surveillance, Epidemiology, and End Results database. They found that while metastatic lymph nodes are still important in informing prognosis, their significance is diminished since HPV has become a predominant cause of cancer.

"Our analysis shows that in this new era of HPV-positive tonsil cancer, we need to find new ways to assess disease prognosis," said Andrew Sikora, MD, Assistant Professor, Otolaryngology and co-author on this study. "This is further evidence that HPV-positive head and neck cancer is a disease distinct from the traditional 'smoker-drinker' head and neck cancer case."


'/>"/>
Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related medicine news :

1. Paralyzed Patients Use Mind to Move Robotic Arm
2. Robotic-assisted prostate cancer surgery drives up costs, UPMC study finds
3. Esophageal Cancer Surgery Can Leave Lingering Health Problems, Study Says
4. Optimal care of bariatric surgery patients vital for long-term health and well-being
5. Codeine After Surgery Could Endanger Certain Kids: Study
6. Surgery Rates Rising for Non-Melanoma Skin Cancer: Study
7. Study examines medicare use for Mohs micrographic surgery and surgical excision for skin cancer
8. Weight-Loss Surgery Beat Drugs for Cutting Diabetes in Very Obese
9. Brain Surgery Might Ease Tough-to-Treat OCD
10. Men More Prone to Complications After Brain, Spine Surgery
11. Lower Risk for Bowel Obstruction With Less Invasive Surgery: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... 2016 , ... David J. Dykeman , Ginger Pigott , and ... speak at DeviceTalks West, Dec. 12, 2016, at the Fairmont Newport Beach in California. ... firm’s global Life Sciences & Medical Technology Group have been featured speakers at every ...
(Date:12/8/2016)... Tampa, Fla (PRWEB) , ... December 08, 2016 ... ... offering smarter modes of access for customers and employees that are both engaging ... ChangeGear 7 with Service Smart Technology, the software company revealed today its plans ...
(Date:12/8/2016)... ... 2016 , ... Catalent Pharma Solutions, the leading global provider ... products, today announced that it had joined the Pharmaceutical Supply Chain Initiative (PSCI). ... unite pharmaceutical and healthcare companies that share a vision of better, social, environmental ...
(Date:12/8/2016)... ... December 08, 2016 , ... STAT courier is pleased ... a convenient service for Texas, they are expanding their presence in Dallas. One of ... spree that will bring new jobs to the Dallas and Forth Worth market. STAT ...
(Date:12/8/2016)... ... December 08, 2016 , ... Today’s patients are encouraged to ... mind, SIGVARIS has created a new line of anti-embolism stockings to help prevent ... the benefits of graduated compression when transitioning from recovery to early rehabilitation. , ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... AMSTERDAM , December 8, 2016 Information ... TM metrics in Scopus , the world,s largest ... free access to comprehensive metrics for journals from over 5,000 publishers. ... publish, which journals to subscribe to and when to adjust a ... , , ...
(Date:12/8/2016)... 2016 According to the research report, ... is expected to be worth US$9.7 bn by the ... Between the forecast years of 2016 and 2024, the global ... The leading players operating in the global diabetes injection pens ... plc., Biocon Ltd., and Sanofi S.A. Transparency Market Research reports ...
(Date:12/8/2016)... 2016 According to a new market research report ... Therapeutic (Pain, Insulin)), End Use (Sports, Fitness, RPM), Type (Smart watch, Patch), ... global market, in terms of value, is projected to reach 12.14 Billion ... 18.0% during the forecast period. Continue Reading ... ...
Breaking Medicine Technology: