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Risk threshold of daily alcohol intake and drinking duration in liver injury?
Date:5/20/2008

Alcoholic threshold effect rather than a dose-response effect on mortality from alcohol-related liver injury. Alcohol intake, rather than the type of alcoholic beverage, was more significant to liver injury.

This study, performed by a team led by by Professor You-Ming Li from Zhejiang University, is described in a research article to be published on April 7, 2008 in the World Journal of Gastroenterology.

The study shows that the risk threshold of daily alcohol intake and the duration of drinking inducing alcohol-related liver injury is 20 g and 5 years in the island population of China. Liver injury induced by obesity should be concerned.

In the view of the authors, to date no clear explanation has existed to evaluate alcohol-related liver injury in China's island population.

The island population east of China is a specific cluster population. Their alcohol consumption is very high compared to that of the mainland population. However, there is a lack of population-based alcoholic liver disease (ALD) studies on China's islands.

The authors conducted a population-based case-control study to investigate the association of alcohol dose, duration of drinking and obesity with liver injury in the island population east of China.

The results will be useful in further analyzing the differences between the island population and the inland population, in terms of drinking habits, diet habits, life and work pressure and genotype. The island population should be further studied in follow-up research.


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Contact: Jing Zhu
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

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