Navigation Links
Risk takers, drug abusers driven by decreased ability to process dopamine
Date:12/29/2008

ion between dopamine receptors and the novelty-seeking personality trait.

"Novelty-seeking personality traits are a major risk factor for the development of drug abuse and other unsafe behaviors," Zald and his colleagues wrote.

"Our research suggests that in high novelty-seeking individuals, the brain is less able to regulate dopamine, and this may lead these individuals to be particularly responsive to novel and rewarding situations that normally induce dopamine release," Zald said.

Previous research in rodents showed that some respond differently to novel environments. Those who explore novel environments more are also more likely to self-administer cocaine when given the chance. Dopamine neurons fire at a higher rate in these novelty-responsive rodents, and the animals also have weak autoreceptor control of their dopamine neurons. Zald and colleagues speculated that the same relationships would be seen in humans.

The researchers used positron emission topography to view the levels of dopamine receptors in 34 healthy humans who had taken a questionnaire that measured the novelty-seeking personality trait. The questionnaire measured things such as an individual's preference for and response to novelty, decision-making speed, a person's readiness to freely spend money, and the extent to which a person is spontaneous and unconstrained by rules and regulations. The higher the score, the more likely the person was to be a novelty seeker.

The researchers found that those that scored higher on the novelty-seeking scale had decreased dopamine autoreceptor availability compared to the subjects that scored lower.


'/>"/>

Contact: Melanie Moran
melanie.moran@vanderbilt.edu
615-322-2706
Vanderbilt University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. National Network to End Domestic Violence Fund Introduces New Tool to Outsmart Abusers and Stalkers in Todays High-Tech World
2. Former substance abusers rarely relapse after organ transplantation
3. Computer Program Helps Drug Abusers Stay Clean
4. National Survey Shows Employee Fears About Consumer-Driven Health Plans on Decline
5. Disabilities Rising Among Workers; Need for Employer-Driven Disability Awareness, Support Efforts Also Increases
6. Blue Cross And Blue Shield Association Survey Shows Consumer Driven Health Plan Enrollees Are Taking More Control of Their Healthcare
7. UniCare Introduces Consumer-Driven Health Products to Give Consumers a Bigger Role in Health Care Decisions
8. Anthem Blue Cross and Blue Shield in Virginia Introduces New Generation of Consumer Driven Health Products
9. Consumer Driven Healthcare Continues To Make Its Mark on Indianapolis Market
10. World Health Report Rankings Driven by Ideology, Skewed Data
11. New EBRI/Commonwealth Fund Research: Enrollment in Consumer-Driven Plans Remains Low, Survey Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... Grants Pass, OR (PRWEB) October 22, 2014 ... while Southern California’s fresh water supply runs dangerously low, ... climate change. Southern Oregon’s rivers, despite the lowest mountain ... fast even in late summer and early autumn.* That ... Urness, authors of the new book “Hiking Southern Oregon,” ...
(Date:10/22/2014)... Healthcare professionals who are looking for ... home or on-the-go via laptops, tablets or mobile ... premium Seminar-on-Demand CE courses. The new courses add ... hours of CE course offerings, allowing therapy ... such a diverse library, there’s something for everyone. ...
(Date:10/22/2014)... Although there are only 24 hours in a day, that ... trouble finding time within their busy schedules for exercise and fitness. ... time to get in shape. Here are five ways you can ... , Change Up Your Commute , Consider riding a bike or ... into your daily routine. If you must use your car to ...
(Date:10/22/2014)... Prussia, PA (PRWEB) October 22, 2014 ... recognized as an industry leader with over 25 years ... winning team leader in the areas related to EDI, ... Mr. Carlson is an Editorial Advisory Board member for ... Council Educator. Blue Fin Group is a management ...
(Date:10/22/2014)... By Steven Reinberg ... -- Infants who quickly add weight and length may be ... study suggests. In adults, certain genes have been linked ... promote proportionate gains in fat and lean muscle, the researchers ... be heavier and taller. By ages 2 and 3, however, ...
Breaking Medicine News(10 mins):Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Rich Carlson and Marc Duey to Hold Workshop at CBI’s Specialty Pharmacy and Distribution Networks Conference 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2
... for health services were meant to motivate health care workers ... in Healthcare. According to researchers, these // ... keep manipulation tactics at bay. ,Gwyn Bevan and ... lauded the target based assessment, but have gone further to ...
... of breast cancer or those who suspect it, feel awkward to ... // ,The Prof says that in the UK alone, the ... and nearly 70 succumb to it. This is also because nearly ... to an irrevocable stage. ,Men should watch out for a ...
... International Journal of Cancer on February 17, 2006 tries to ... the level of physical activity in women. // The prospective ... link. ,Experts felt that since exercise is known ... the gastrointestinal transit time, it might also play a constructive ...
... to reduce smoking amongst children have been lauded with a ... an added thrust to the campaign.// Smoking hampers their ... the drive, by augmenting the anti-smoking budget, Hawaii has regressed ... cigarettes have not been hiked, unfortunately, which might have deterred ...
... Research seems to compliment Acupressure over physical therapy, to ... Taiwan University // have acclaimed Acupressure’s success with statistics ... to physical therapy with the effect lasting up to ... pain were treated with six sessions of acupressure, and ...
... to curb the spread of AIDS/HIV, which is haunting the ... authorities from over 20 different countries in the Asia Pacific ... a universal access to AIDS/HIV treatment and prevention would be ... the failure of the WHO target to expand AIDS treatment ...
Cached Medicine News:Health News:Women, Exercise and Colon Cancer 2
(Date:10/25/2014)... ARBOR, Mich. , Oct. 24, 2014 Advanced ... second quarter (ending September 26, 2014) financial results on Monday, ... will be released after the close of the market and ... discuss the results at 4:30 p.m. EDT on the same ... Richard Kurtz (CEO and Director), Rob Risser ...
(Date:10/25/2014)... , Oct. 24, 2014  The National ... the latest results achieved by Kentucky,s ... The National Precursor Log Exchange ... the point of sale and helps flag meth ... agents often set up NPLEx "watch lists" that ...
(Date:10/25/2014)... DUBLIN , October 24, 2014 /PRNewswire/ ... Markets ( http://www.researchandmarkets.com/research/wdq92g/global_and ) has announced the addition ... Industry Report 2014"  report to their ... ,The Global and Chinese Acne Medication Industry ... study on the current state of the ...
Breaking Medicine Technology:Advanced Photonix to Webcast Fiscal 2015 Second Quarter Earnings 2Kentucky's NPLEx Technology Making Significant Progress 2Global and Chinese Acne Medication Industry Report 2014 2Global and Chinese Acne Medication Industry Report 2014 3
... SphygmoCor system plays key role in discovery, ... A,new study of more than 10,000 patients, conducted ... United Kingdom using AtCor Medical Holdings,Limited,s SphygmoCor(R) has ... as having "high normal" systolic blood pressure through,traditional ...
... 28 ACCESS PHARMACEUTICALS, INC.,(OTC Bulletin Board: ... oral and,poster presentations on its Cobalamin(TM) technology ... to Clinical Practice, taking,place from May 26-28 ... B12-Polymer Conjugates as Constructs for Targeted Tumor ...
Cached Medicine Technology:New Study Linking 'High Normal' Blood Pressure to Significant Cardiovascular Risk 2New Study Linking 'High Normal' Blood Pressure to Significant Cardiovascular Risk 3Access Pharmaceuticals Presents New Data on the Company's Cobalamin(TM) Technology at an International Polymer Therapeutics Symposium 2Access Pharmaceuticals Presents New Data on the Company's Cobalamin(TM) Technology at an International Polymer Therapeutics Symposium 3
... Arthrotek® Precision Hand Instruments were developed in ... feel, while still having an instrument with ... without the fear of the bending or ... and manufactured to conform to the surgeon's ...
... Hand Instruments were developed in surgeon's desire ... still having an instrument with the strength ... fear of the bending or breaking. Arthrotek ... to conform to the surgeon's hand. This ...
... Arthrotek® Precision Hand Instruments were developed in ... feel, while still having an instrument with ... without the fear of the bending or ... and manufactured to conform to the surgeon's ...
... USS Sports Medicine POLYSORB Meniscal Stapler XLS ... two resorbable legs of the staple. The ... tissue, specifically the meniscus. The staple is ... derivative of lactic acid and glycolic acids. ...
Medicine Products: