Navigation Links
Risk for patients in the intensive care unit clearly reduced
Date:3/10/2010

To get life-threatening diseases under control, patients in the intensive care unit usually are administered many medications at the same time. Even for experts, it is difficult to keep track of the variety of possible side effects and interactions. The team headed by Dr. Thilo Bertsche, director of the cooperation unit for clinical pharmacy at Heidelberg University Hospital, has now shown that physicians can reduce serious events resulting from drug interactions by about half with the help of the "AiDKlinik" drug information system. The results of the study were published in the prestigious journal "Intensive Care Medicine".

One of the few effective drug information systems in the world

"We previously verifiably improved physician's prescriptions with our "AiDKlinik" tool and showed that no new errors were introduced. However, we have now proven that laboratory values and clinical findings are also changed. Not many systems in the world can maintain that they have been able to reduce clinically relevant events due to drug interactions by almost half," says Professor Dr. Walter E. Haefeli, Medical Director of the Department of Clinical Pharmacology and Pharmacoepidemiology at Heidelberg University Hospital.

Erroneous prescriptions, interactions not taken into account, contraindications, or restrictions on use are often the cause of avoidable adverse drug effects. The "AiDKlinik" drug information system developed at the hospital helps to reduce such undesired events. While the condition of patients in the ICU frequently requires that they be given certain drugs despite known interactions, the goal is to prevent clinically relevant events that could endanger the patients.

Half as many risk situations for ICU patients

Data from 265 patients were examined for the study in an intensive care unit at Heidelberg University Hospital. The study included only patients who were given eight or nine drugs simultaneously. On the second day after admission, the prescribed medication was checked using the drug information system. At the next rounds, the physicians responsible for the patient were given a report on potential drug interactions and, if necessary, concrete recommendations to avoid clinical effects.

Using this procedure, the adverse events in connection with drug interactions were reduced by 43 percent. Some of the most critical events, such as changes in the ECG and electrolyte imbalances, which can lead to severe arrhythmia, were reduced by 64 percent and 80 percent respectively. In addition, fewer patients needed additional drugs to treat side effects.

"AiDKlinik" a development from hospital practice

The "AiDKlinik" drug information system was developed in recent years by the Department of Clinical Pharmacology and Pharmacoepidemiology at Heidelberg University Hospital in conjunction with the hospital pharmacy and Medizinische Medien Informations GmbH (MMI, Neu-Isenburg) and has since been continuously expanded. It is an Internet-based electronic guideline that can be used by hospitals and practices. Numerous relevant patient data such as age, renal function, pregnancy, etc. are included in information processing. The information system currently includes around 64,000 drugs and is implemented in the entire university hospital. The information stems from the Pharmindex database, issued by the medical publishing house Medizinische Medien Informations GmbH and is updated every 14 days.


'/>"/>

Contact: Dr. Thilo Bertsche
klinischepharmazie@med.uni-heidelberg.de
062-215-639-537
University Hospital Heidelberg
Source:Eurekalert  

Related medicine news :

1. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
2. Comparison of obstetric outcomes between on-call and patients own obstetricians
3. Vision restoration therapy shown to improve brain activity in brain injured patients
4. Diabetes appears to increase risk of death for patients with acute coronary syndromes
5. Ambulatory oxygen rarely a benefit in COPD patients without resting hypoxemia
6. Restricting Blood Flow May Help Heart Bypass Patients
7. Patients with Medicaid and those lacking insurance have higher risk of advanced laryngeal cancer
8. Study provides hope that some transplant patients could live free of antirejection drugs
9. Study provides hope that some transplant patients could live free of anti-rejection drugs
10. Longer ambulance journeys boost death risk for seriously ill patients
11. Expenses Overshadow Optimism for Kidney Failure Patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Risk for patients in the intensive care unit clearly reduced
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... The threat ... went to work for a company involved in the underground testing of nuclear weapons. ... “Dying for Answers: Expendable Workers of the Cold War Nuclear Testing,” Clayton exposes the ...
(Date:2/27/2017)... ... February 27, 2017 , ... ... on laser diffraction analysis as a tool to characterize particle size distributions in ... to obtain improved results and novel scientific findings. It describes methods of optimized ...
(Date:2/27/2017)... ... February 27, 2017 , ... Texas based retail electric company ... Power's RCE (Residential Customer Equivalent) count exceeds 150,000. , Discount Power ... customers and 2,250 RCEs at the time of acquisition. In the three years ...
(Date:2/27/2017)... Francisco, CA (PRWEB) , ... February 27, 2017 ... ... clinic serving San Francisco and environs, is proud to announce an upgrade to ... information on the upgraded Yelp page on topics as diverse as Platelet Rich ...
(Date:2/26/2017)... ... February 26, 2017 , ... Today, ... the 7th Edition of International Social Design Awards. , The 7th A' ... System Designers, Governments and Institutions worldwide with realized projects and conceptual works. , ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... Feb. 27, 2017   Royal Philips ... global leader in health technology, today announced 510(k) ... (FDA) to market its ElastQ Imaging capability, further ... ultrasound systems. ElastQ Imaging enables simultaneous imaging of ... essential for the diagnosis of various liver conditions. ...
(Date:2/27/2017)... , Feb. 27, 2017  Infinity Pharmaceuticals, Inc. ... the Cowen and Company 37 th Annual Healthcare ... ET in Boston, MA. A ... the Investors/Media section of Infinity,s website at www.infi.com ... the event. About Infinity,Infinity is an innovative ...
(Date:2/27/2017)... 27, 2017 A recent research report published ... market alone is expected to reach a value of $55.8 billion ... along with 28 states have legalized marijuana for medical uses. In ... Florida , North Dakota , ... to use the drug in medical applications such as chemotherapies and ...
Breaking Medicine Technology: