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Risk for patients in the intensive care unit clearly reduced
Date:3/10/2010

To get life-threatening diseases under control, patients in the intensive care unit usually are administered many medications at the same time. Even for experts, it is difficult to keep track of the variety of possible side effects and interactions. The team headed by Dr. Thilo Bertsche, director of the cooperation unit for clinical pharmacy at Heidelberg University Hospital, has now shown that physicians can reduce serious events resulting from drug interactions by about half with the help of the "AiDKlinik" drug information system. The results of the study were published in the prestigious journal "Intensive Care Medicine".

One of the few effective drug information systems in the world

"We previously verifiably improved physician's prescriptions with our "AiDKlinik" tool and showed that no new errors were introduced. However, we have now proven that laboratory values and clinical findings are also changed. Not many systems in the world can maintain that they have been able to reduce clinically relevant events due to drug interactions by almost half," says Professor Dr. Walter E. Haefeli, Medical Director of the Department of Clinical Pharmacology and Pharmacoepidemiology at Heidelberg University Hospital.

Erroneous prescriptions, interactions not taken into account, contraindications, or restrictions on use are often the cause of avoidable adverse drug effects. The "AiDKlinik" drug information system developed at the hospital helps to reduce such undesired events. While the condition of patients in the ICU frequently requires that they be given certain drugs despite known interactions, the goal is to prevent clinically relevant events that could endanger the patients.

Half as many risk situations for ICU patients

Data from 265 patients were examined for the study in an intensive care unit at Heidelberg University Hospital. The study included only patients who were given eight or nine dru
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Contact: Dr. Thilo Bertsche
klinischepharmazie@med.uni-heidelberg.de
062-215-639-537
University Hospital Heidelberg
Source:Eurekalert  

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