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Risk factors for CCSVI are similar to risk factors for developing MS, UB study shows
Date:11/30/2011

Risk Factors for CCSVI are Similar to Risk Factors for Developing MS, UB Study Shows

Summary:

  • A vascular condition called chronic cerebrospinal venous insufficiency (CCSVI), which has attracted global attention as possibly being correlated with MS has, for the first time, been studied for the presence of risk factors in subjects who do not have a neurological disease.
  • A preliminary University at Buffalo study of 252 volunteers has found an association between CCSVI and as many as three characteristics widely viewed as possible or confirmed MS risk factors. They are: infectious mononucleosis, irritable bowel syndrome and smoking.
  • The UB researchers conclude that the association of CCSVI risk factors with MS risk factors in subjects without known central nervous system disease is significant and warrants further study.

BUFFALO, N.Y. The first study to investigate risk factors for the vascular condition called CCSVI (chronic cerebrospinal venous insufficiency) in volunteers without neurological disease has identified what the researchers call a remarkable similarity between this condition and possible or confirmed risk factors for multiple sclerosis (MS).

The University at Buffalo study investigated associations between CCSVI and demographic, clinical and environmental risk factors in a large control group of volunteers who did not have known central nervous system disease.

"Our results suggest that risk factors for CCSVI in this group of volunteers are remarkably similar to those of possible or confirmed importance to MS, but we do not yet understand the whole story," says Robert Zivadinov, MD, PhD, FAAN, professor of neurology at the UB School of Medicine and Biomedical Sciences, and senior author on the study.

He discusses the study's results in the video at http://www.youtube.com/watch?v=Vip7QAtlfqE.

Published today (Nov. 30)
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Contact: Ellen Goldbaum
goldbaum@buffalo.edu
716-645-4605
University at Buffalo
Source:Eurekalert

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