Navigation Links
Rising rates of severe and fatal sepsis during labor and delivery
Date:9/23/2013

San Francisco, CA. (September 23, 2013) Rates of severe sepsis and deaths from sepsis among U.S. women hospitalized for delivery have risen sharply over the last decade, reports a study in the October issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

"Maternal severe sepsis and sepsis-related deaths are increasing in the United States," concludes the report by Dr Melissa E. Bauer of University of Michigan Health System, Ann Arbor, and colleagues. Although the study identifies certain groups of women at increased risk, severe sepsis and death can occur during labor and delivery even in women with no recognized risk factors.

Rising Rates of Severe and Fatal Sepsis among Women in Labor

Using a national hospital database (the Nationwide Inpatient Sample), Dr Bauer and colleagues analyzed information on US hospitalizations for delivery from 1998 through 2008. Their goal was to identify trends in the frequency of maternal sepsis, including severe and fatal cases.

Sepsis is a serious medical condition in which the body has a system-wide inflammatory reaction to bacterial or other infections. In severe cases, sepsis can lead to multiple organ failure and death.

Extrapolated to the entire United States, the data represented approximately 45 million hospitalizations for delivery. Overall, sepsis occurred at a rate of 1 per every 3,333 women hospitalized for delivery. This rate did not change significantly over the 11-year period studied.

Severe sepsis occurred in about 1 out of 11,000 women. During the study period, the rate of severe sepsis approximately doubled: from about 1 in 15,400 to 1 in 7,250 women in labor.

Fatal sepsis occurred in about 1 out of 106,000 cases. Both severe and fatal sepsis increased by about 10 percent per year.

For Many Women with Severe Sepsis, No Known Risk Factors

The study identified several medical conditions associated with an increased risk of severe sepsis, including congestive heart failure, chronic liver and kidney disease, and lupus (systemic lupus erythematosus). Cerclage, or "cervical stitch"a procedure performed to prevent premature birthwas also a significant risk factor.

Other factors associated with an increased risk of severe sepsis were similar to those for other complications of labor and delivery, including older maternal age, African American race/ethnicity, and Medicaid insurance. However, none of these factors explained more than six percent of cases of sepsis during labor and delivery. Many women who developed severe or fatal sepsis had no known risk factors.

Sepsis is an increasing cause of complications and death among women in developed countries. Recent U.K. data have shown that deaths due to sepsis have nearly doubled over the past decade, "making sepsis the leading cause of direct maternal death in the United Kingdom," according to the authors.

The new study shows similar sharp increases in severe sepsis and sepsis-related deaths in the United States. The database study permits no conclusions as to what's causing the rise in severe sepsis among U.S. women. However, Dr Bauer and coauthors write, "This increase may have been due to similar factors as those identified in the United Kingdom such as increasing microbial resistance, obesity, smoking, substance abuse, and poor general health."

The results also suggest that, while certain conditions increase the risk of severe and fatal sepsis, many cases occur in women with no recognized risk factors. That finding "underscores the need for developing systems of care that increase sensitivity for disease detection across the entire population," the researchers conclude.


'/>"/>

Contact: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. St. Vincent Hospital and Lakeview Health Join Forces Against Rising Jacksonville Addiction
2. Kamut International Responds to New Book, "Grain Brain, The Surprising Truth About Wheat, Carbs, and Sugar - Your Brain's Silent Killers"
3. Rising Bird, Inc. Secures $1,250,000 Credit Facility for EU Montage USA Division
4. Virginia Tech Carilion researchers find surprising relationships in brain signaling
5. A Unique Health Solution for Canada’s Rising Obesity Epidemic: TrekDesk Treadmill Desk
6. Virtual Doctors Help Men Avoid Rising Medical Health Insurance Deductibles With New, Male Orientated Doctor Health Service.
7. Indiana’s Largest Optical Retailer Forges Exclusive Partnership with Rising Philanthropic Eyewear Brand
8. ASSURE study of experimental agent to raise HDL yields disappointing and surprising results
9. Skin cell defect is surprising allergy trigger
10. Neurologist Dr. Marisa C. Chang of Neurological Associates of West Los Angeles Has Been Named a Southern California Rising Star by Super Doctors®
11. Diet Doc Medically Supervised Weight Loss Diets Help Fight Rising Mortality Rates with Their New Best Weight Loss Supplements and Smoothie Diet Recipes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Lafayette, California (PRWEB) , ... ... ... a pioneer in the patient payment industry today announced its strategic partnership ... and health system workflows. , The two companies’ proven, proprietary technology combine ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
Breaking Medicine Technology: