Navigation Links
Rigel Receives Milestone Payment from Daiichi Sankyo for Cancer Ligase Target

SOUTH SAN FRANCISCO, Calif., Dec. 23 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced that it has received a milestone payment from Daiichi Sankyo Co., Ltd. as part of their collaboration to research and develop cancer treatments aimed at selectively inhibiting ligases, which are intrinsic to cancer cell growth and proliferation. The compound, as yet unnamed, targets cell division.

"We believe that ubiquitin ligases represent a promising area of medical research, particularly in the field of novel therapeutics for the treatment of cancer," said Donald G. Payan, chief scientific officer of Rigel. "We are pleased that Daiichi Sankyo has achieved the milestone and look forward to their efforts in the next upcoming studies and, potentially, future clinical development."

Rigel and Daiichi Sankyo have an ongoing research collaboration aimed at identifying small molecule drug candidates against a ligase target that controls cancer cell proliferation through protein degradation. Rigel's early research efforts uncovered a number of compounds that appeared to inhibit replication of several types of tumor cells. Daiichi Sankyo's research has advanced some of Rigel's early work and has resulted in several milestone payments previously announced through this collaboration.

About Rigel (

Rigel is a clinical-stage drug development company that discovers and develops novel, small-molecule drugs for the treatment of inflammatory/autoimmune diseases and metabolic diseases. Rigel's pioneering research focuses on intracellular signaling pathways and related targets that are critical to disease mechanisms. Rigel's productivity has resulted in strategic collaborations with large pharmaceutical partners to develop and market its product candidates. Rigel has product development programs in inflammatory/autoimmune diseases, such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer.

This press release contains "forward-looking" statements, including statements related to the potential efficacy of novel therapeutics for the treatment of cancer and the clinical development of the lead compound discovered by Rigel and identified by Daiichi for further development. Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Words such as "believe," "potential," and similar expressions are intended to identify these forward-looking statements. These forward-looking statements are based upon Rigel's current expectations and involve risks and uncertainties. There are a number of important factors that could cause Rigel's results to differ materially from those indicated by these forward-looking statements, including, without limitation, risks associated with the timing and success of preclinical studies and clinical trials, and potential problems that may arise in the research and development and approval process, as well as other risks detailed from time to time in Rigel's filings with the SEC, including its Form 10-Q for the quarter ended September 30, 2009. Rigel does not undertake any obligation to update forward-looking statements and expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein.

    Contact: Raul Rodriguez
    Phone: 650.624.1302

    Media Contact: Susan C. Rogers, Alchemy Consulting, Inc.
    Phone: 650.430.3777

SOURCE Rigel Pharmaceuticals, Inc.

SOURCE Rigel Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Decision Resources Updated Rheumatoid Arthritis Report Now Includes Forecast for Rigel Pharmaceuticals Fostamatinib Disodium
2. Rigel Announces Second Quarter 2009 Financial Results
3. Rigel to Host Conference Call to Discuss Results of Its Phase 2b TASKi3 Clinical Trial of R788 in Rheumatoid Arthritis
4. Rigel to Present at Jefferies Healthcare Conference
5. Rigels R788 Evaluated in Phase 2 Trial in Multiple Cancers
6. Rigel to Present at JMP Securities Research Conference
7. Rigel to Present at Barclays Capital Healthcare Conference
8. Rigel Announces Fourth Quarter and Year End 2008 Financial Results
9. Rigel to Present at BIO CEO & Investor Conference
10. Rigel to Host Conference Call on February 3, 2009
11. Rigel to Present at Keystone Symposia Conference
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... ... by athletic teams looking to maximize recovery through quality sleep. Tim DiFrancesco, training ... consistently get a better night’s sleep. ChiliPad precisely regulates the surface temperature of ...
(Date:11/30/2015)... ... ... Dr. Seth D. Margulies specializes in orthodontics and is based in Perth ... the best available orthodontic experience in the area. Dr. Margulies has met all ... the branch of dentistry that specializes in the diagnosis, prevention, and treatment of dental ...
(Date:11/30/2015)... VA (PRWEB) , ... November 30, 2015 , ... ... Association of Poison Control Centers’ National Poison Data System (NPDS) reveals that in ... managed almost 3 million cases, over two million of which were human exposure ...
(Date:11/30/2015)... ... November 30, 2015 , ... The American Society for Clinical Pathology (ASCP) ... AIDS Day 2015. On Nov. 30, ASCP shared its “Give a minute. Get tested. ... Day and the importance of getting tested for HIV. , ASCP has asked members ...
(Date:11/30/2015)... ... November 30, 2015 , ... While powdered supplements and drinks can reduce ... an inventor from Chesterfield, Va., has found an easy to keep track of the ... to measure powdered contents in a canister or other container handy and readily accessible. ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... 30, 2015  QT Vascular Ltd., together with its ... its subsidiaries, TriReme Medical LLC and Quattro Vascular Pte. ... the design, assembly and distribution of advanced therapeutic solutions ... pleased to announce that a three-judge panel of ... for the Federal Circuit ("Federal Circuit") has unanimously granted ...
(Date:11/30/2015)... CITY, Calif. , Nov. 30, 2015 Nevro ... that is providing innovative evidence-based solutions for the treatment of ... Board (PTAB) at the U.S. Patent and Trademark Office (USPTO) ... of U.S. Patent No. 8,359,102 (the ,102 patent).  ... 2015, a unit of Boston Scientific Corporation filed two petitions ...
(Date:11/30/2015)... Calif. , Nov. 30, 2015 /PRNewswire/ ... today that Matt Hogan , Chief ... Oppenheimer Healthcare Conference on Tuesday, December 8 ... is being held at the Westin Grand ... also be available for one-on-one meetings at ...
Breaking Medicine Technology: