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Rigel Receives Milestone Payment from Daiichi Sankyo for Cancer Ligase Target
Date:12/23/2009

SOUTH SAN FRANCISCO, Calif., Dec. 23 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced that it has received a milestone payment from Daiichi Sankyo Co., Ltd. as part of their collaboration to research and develop cancer treatments aimed at selectively inhibiting ligases, which are intrinsic to cancer cell growth and proliferation. The compound, as yet unnamed, targets cell division.

"We believe that ubiquitin ligases represent a promising area of medical research, particularly in the field of novel therapeutics for the treatment of cancer," said Donald G. Payan, chief scientific officer of Rigel. "We are pleased that Daiichi Sankyo has achieved the milestone and look forward to their efforts in the next upcoming studies and, potentially, future clinical development."

Rigel and Daiichi Sankyo have an ongoing research collaboration aimed at identifying small molecule drug candidates against a ligase target that controls cancer cell proliferation through protein degradation. Rigel's early research efforts uncovered a number of compounds that appeared to inhibit replication of several types of tumor cells. Daiichi Sankyo's research has advanced some of Rigel's early work and has resulted in several milestone payments previously announced through this collaboration.

About Rigel (www.rigel.com)

Rigel is a clinical-stage drug development company that discovers and develops novel, small-molecule drugs for the treatment of inflammatory/autoimmune diseases and metabolic diseases. Rigel's pioneering research focuses on intracellular signa
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SOURCE Rigel Pharmaceuticals, Inc.
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