Date:10/31/2008

y known, commercially valuable antibiotics exert their effects by binding to the bacterial ribosome. The Company's integrated research strategy, which combines state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibiotics that can be used for the treatment of either community- or hospital-acquired infections. Radezolid (RX-1741), an oxazolidinone, is an oral/IV agent for treatment of serious Gram-positive infections. The Rx-04 discovery program is developing novel classes of antibiotics active against multi-drug resistant Gram-negative bacteria and the Rx-02 discovery program is focused on developing an IV/oral macrolide active against methicillin-resistant S. aureus, multidrug-resistant Streptococus pneumonia and S. pyogenes. Additionally, Rib-X is developing delafloxacin, (RX-3341), an anionic fluoroquinolone active against a broad spectrum of bacteria, including quinolone-resistant Gram-positive bacteria and MRSA. Both radezolid and delafloxacin are currently in Phase 2 clinical trials.

For more information on the Rib-X mission and the pipeline, please visit the Company website at http://www.rib-x.com.

About The Connecticut Women's Hall of Fame

The Connecticut Women's Hall of Fame is an educational outreach organization whose mission is to honor publicly the achievement of Connecticut women, preserve their stories, educate the public and inspire the continued achievements of women and girls. Founded in 1994 in Hartford, Connecticut, the Hall fills the void that traditional curricula still fail to address and today stands as the state's premier source for women's history with over 85 Inductees. These women's lives and accomplishments are celebra
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SOURCE Rib-X Pharmaceuticals, Inc. Copyright©2008 PR Newswire. All rights reserved

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