Navigation Links
Rhode Island Hospital study identifies fish oil's impact on cognition and brain structure
Date:8/17/2011

PROVIDENCE, R.I. Researchers at Rhode Island Hospital's Alzheimer's Disease and Memory Disorders Center have found positive associations between fish oil supplements and cognitive functioning as well as differences in brain structure between users and non-users of fish oil supplements. The findings suggest possible benefits of fish oil supplements on brain health and aging. The results were reported at the recent International Conference on Alzheimer's Disease, in Paris, France.

The study was led by Lori Daiello, PharmD, a research scientist at the Rhode Island Hospital Alzheimer's Disease and Memory Disorders Center. Data for the analyses was obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a large multi-center, NIH-funded study that followed older adults with normal cognition, mild cognitive impairment, and Alzheimer's Disease for over three years with periodic memory testing and brain MRIs.

The study included 819 individuals, 117 of whom reported regular use of fish oil supplements before entry and during study follow-up. The researchers compared cognitive functioning and brain atrophy for patients who reported routinely using these supplements to those who were not using fish oil supplements.

Daiello reports that compared to non-users, use of fish oil supplements was associated with better cognitive functioning during the study. However, this association was significant only in those individuals who had a normal baseline cognitive function and in individuals who tested negative for a genetic risk factor for Alzheimer's Disease known as APOE4. This is consistent with previous research.

The unique finding, however, is that there was a clear association between fish oil supplements and brain volume. Consistent with the cognitive outcomes, these observations were significant only for those who were APOE4 negative.

Daiello says, "In the imaging analyses for the entire study population, we found a significant positive association between fish oil supplement use and average brain volumes in two critical areas utilized in memory and thinking (cerebral cortex and hippocampus), as well as smaller brain ventricular volumes compared to non-users at any given time in the study. In other words, fish oil use was associated with less brain shrinkage in patients taking these supplements during the ADNI study compared to those who didn't report using them."

Daiello continues, "These observations should motivate further study of the possible effects of long-term fish oil supplementation on important markers of cognitive decline and the potential influence of genetics on these outcomes."

The research team included Brian Ott M.D., director of the Rhode Island Hospital and Memory Disorders Center, Assawin Gongvatana Ph.D., Shira Dunsiger Ph.D. and Ronald Cohen Ph.D. from The Miriam Hospital and the Brown University Department of Psychiatry and Human Behavior (Gonvatana and Cohen), and Department of Behavior and Social Sciences (Dunsiger).


'/>"/>

Contact: Nancy Cawley Jean
njean@lifespan.org
Lifespan
Source:Eurekalert

Related medicine news :

1. Rhode Island and Miriam researchers say patient gender may influence nuclear stress test referrals
2. Rhode Island Hospital fellow receives funding to support research in myocardial perfusion
3. Paper by Rhode Island Hospital physician selected among best of 2010 by JACR
4. Women & Infants launches Rhode Island Network for Pelvic Floor Disorders
5. Rhode Island Hospital physician receives national award for research
6. Rhode Island Settlement Reflects Homeowner Liability for Serving Alcohol to Those Under 21, Says Providence Lawyer Mark Gemma
7. What will climate change and sea level rise mean for barrier islands?
8. Sea grant awards more than $1.1 million for research under EPAs Long Island Sound study
9. Scientists discover key to Christmas Islands red crab migration
10. Cyberknife of Long Island Destroys Prostate Cancer Non-Invasively Using Radiosurgery
11. Relevant Public Relations President Barton Horowitz of Staten Island, N.Y., Chamber CEO Linda Baran Applauded By Congressman McMahon as SBA Honorees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... CA (PRWEB) , ... January 16, 2017 , ... ... manuscript in the Aesthetic Surgery Journal , the official journal of The ... conducted on lower eyelid retraction surgery. The procedure is designed to correct drooping, ...
(Date:1/16/2017)... ... , ... NexTec Group has been selected as a member of the Bob ... in the field of midmarket financial software. , Members of the VAR Stars were ... not based on revenue and those firms chosen represent a wide range of size ...
(Date:1/15/2017)... ... January 15, 2017 , ... "On Tour is a music themed slideshow production ... said Christina Austin - CEO of Pixel Film Studios. , On Tour’s new ... style and animation of their slideshows. Place each slide on top of another slide ...
(Date:1/14/2017)... MN (PRWEB) , ... January 14, 2017 , ... ... present the distinctions among their expanding line of activated charcoal products. With more ... the importance of categorizing their products according to how they cater to specific ...
(Date:1/13/2017)... , ... January 13, 2017 , ... The 18th European ... America hotel on March 3-4, 2017. This Congress is expertly designed to meet ... management of patients with lung cancer. , Chaired by Dr. Giorgio V. Scagliotti, Professor ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... Bill is an internationally experienced medical device industry executive who has ... medical device companies, including Smith & Nephew, Angiodynamics, Orthovita and Stryker. ... building successful businesses in the sector and has worked in ... North America . ... Educated at the University of Edinburgh (Dental Surgery), University ...
(Date:1/16/2017)... Tenn. , Jan. 16, 2017  Cumberland Pharmaceuticals ... of Kenneth J. Krogulski , CFA to its ... Executive Officer of Berkshire Asset Management LLC . ... a 30-year-old independent SEC registered investment advisory firm with ... has over 37 years, experience in security analysis and ...
(Date:1/15/2017)... 14, 2017 ImmersiveTouch Inc., the global leader ... announced recent appointments strengthening their Executive Management team.  ... as Chief Executive Officer, Jay Banerjee as ... President of Sales and Jia Luo , PhD ... Mr. Bowman has 20 years experience commercializing ...
Breaking Medicine Technology: