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Rhode Island Hospital lands $11.1M grant from National Institutes of Health
Date:10/29/2007

and chairman of the Department of Orthopedics and rehabilitation at Alpert Medical School.

The new COBRE will focus on cartilage and joint health, disease mechanisms and repair strategies, according to center director and principal investigator Qian Chen, PhD, director of cell and molecular biology and head of orthopedic biology at Rhode Island Hospital. He is also a professor of medical science and the Michael G. Ehrlich Chair in Orthopedic Research at Alpert Medical School.

The aging of the baby boom generation and soaring obesity rates mean we can expect to see a sharp increase in the number of patients with osteoarthritis and other joint diseases, said Chen. Thats why its critical that we not only expand our search for new and better treatments for joint diseases, but that we also recruit and mentor the next generation of orthopedic researchers which our COBRE award allows us to do.

Chen will lead a multidisciplinary team that includes researchers from the departments of orthopedics, emergency medicine, pediatrics, medicine and bioengineering at Rhode Island Hospital and Brown University. Specific research projects will focus on how long bones are built up during skeletal development, how joint cartilage degenerates in adult joint diseases, and how to repair and rebuild healthy cartilage joint.

This grant is proof positive that collaboration in science advances knowledge and improves lives, said Eli Y. Adashi, MD, dean of medicine and biological sciences at Brown. Investigators from five distinct disciplines who work at both the bench and the bedside are joining forces to better understand arthritis and other common musculoskeletal diseases. This collaboration, this bridge between Brown and a major Lifespan partner, Rhode Island Hospital, will benefit the public by producing better methods of treatment and prevention.

The COBRE grant will primarily support these research projects, although some funds will go
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Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-432-1328
Lifespan
Source:Eurekalert

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